diff --git a/textfiles.com/drugs/lsd_chro.txt b/textfiles.com/drugs/lsd_chro.txt new file mode 100644 index 00000000..a4e89e0f --- /dev/null +++ b/textfiles.com/drugs/lsd_chro.txt @@ -0,0 +1,93 @@ +Message-ID: <052314Z17091993@anon.penet.fi> +Newsgroups: alt.drugs +From: an13187@anon.penet.fi (H-Man) +Date: Fri, 17 Sep 1993 05:16:50 UTC +Subject: Weil: LSD and Chromosomes + +Hey all! I just read THE NATURAL MIND by Andrew Weil. Although it dealt +with ACID and MARIJUANA too much for my tastes, I typed up some EXCERPTS +that I thought you'd like. + + |--########>-- H-Man --<########--| + +pp. 44-46: + +Retrospective studies are risky ways of framing hypotheses; they are fraught +with logical traps known to the ancients, and it is remarkable that men of +science still fall for them. + +The saga of LSD and chromosomes is a case in point, for much of the evidence +was of this retrospective sort. The initial hypothesis, first reported in +1967, was based on the observation that LSD users seemed to have a higher +frequency of broken chromosomes in certain white blood cells (lymphocytes) +than "normal" persons (1). The _New England Journal of Medicine_ gave this +observation great prominence in an editorial titled, "Radiomimetic Effects +of LSD," suggesting that the drug mimicked radiation in its damaging effects +on genetic material. Evidence that was more circumstantial then appeared: +LSD was shown to affect chromosomes of cells growing in test tubes; a few +mothers who had used LSD gave birth to deformed babies. The scientific and +lay press gave all these findings front-page attention. The National +Institute of Mental Health eagerly seized upon and disseminated the new +information in a propaganda campaign against LSD. And, for a few months, +use of the drug appeared to decline. + +But throughout this campaign, a number of facts were overlooked. First was +the total absence of any prospective studies supporting the hypothesis. No +one had tested the hypothesis in a legitimate way -- by looking at +chromosomes before exposure to the drug, giving the drug in a controlled +fashion, and then keeping watch on chromosomes. Second was the known fact +that many things affect chromosomal integrity, among them such common drugs +as aspirin and chlorpromazine (Thorazine) and recent viral infections. No +effort was made to control for these other factors in the clinical cases. +Third was the general problem of tissue-culture studies: cells growing in +test tubes do not behave the way cells do in the body. In addition, the +doses of LSD that caused visible changes in chromosomes of tissue-culture +cells were far higher than the doses living cells get when a person takes +an acid trip. Fourth, chromosomal breaks are seen in cells of all people; +the arguments turned on a statistical difference in frequency, not an +all-or-nothing difference, and the frequency of chromosomal breaks in +lymphocytes seems to correlate more directly with laboratory technique than +with other variables. (The technique of preparing lymphocytes to make +chromosomes visible is complicated and likely to produce factitious +changes.) Fifth, the lymphocyte is one of the only cells in which human +chromosomes can ever be seen under the microscope. Even if the changes were +real, they said nothing about the state of chromosomes in other cells (such +as reproductive cells). In fact, through the whole controversy no one +showed _why_ it was bad to have broken chromosomes in your lymphocytes. It +sounds bad, certainly, but one cannot say that it is bad without making a +number of shaky assumptions. + +All of these logical flaws in the medical arguments against LSD were obvious +in 1967. They do not mean that the hypothesis should never have been +published, but surely it should not have been promoted by the medical +profession, the press, and the National Institute of Mental Health without +more thought. And it is significant that these logical flaws were first +pointed out in the _Berkeley Barb_ and other underground newspapers at least +eight months before the _New England Journal of Medicine_ voiced similar +doubts. The necessary prospective studies were not published until the end +of 1969 (2). Not surprisingly, they failed to demonstrate any relationship +between LSD use and chromosomal changes. They generated very little +national publicity. + +This episode ought to be profoundly embarassing to journal editors and +government scientists. At one stroke it created an irreparable gap between +users of drugs and drug experts. Since 1968 I have not met a single user of +hallucinogens who will believe any reports of medical damage associated with +drugs, and the use of hallucinogens has never been higher. + +(1) M. M. Cohen, K. Hirshhorn, W. A. Frosch, "In Vivo and in Vitro +Chromosomal Damage Induced by LSD-25," _New England Journal of Medicine_ 227 +(1967), p. 1043. + +(2) J. H. Tjio, W. N. Pahnke, A. A. Kurland, "LSD and Chromosomes: A +Controlled Experiment," _Journal of the American Medical Association_ 210 +(1969), p. 849. For a recent review of the whole field, see N. I. +Dishotsky, W. D. Loughman, R. E. Mogar, W. R. Lipscomb, "LSD and Genetic +Damage," _Science_ 172 (30 April 1971), p. 431. +------------------------------------------------------------------------- +To find out more about the anon service, send mail to help@anon.penet.fi. +Due to the double-blind, any mail replies to this message will be anonymized, +and an anonymous id will be allocated automatically. You have been warned. +Please report any problems, inappropriate use etc. to admin@anon.penet.fi. + + diff --git a/textfiles.com/drugs/lsd_refs.txt b/textfiles.com/drugs/lsd_refs.txt new file mode 100644 index 00000000..8c0d6c2f --- /dev/null +++ b/textfiles.com/drugs/lsd_refs.txt @@ -0,0 +1,301 @@ + [...only the conclusions of this paper are made publicly available via + anonymous ftp, interested persons should visit their libraries...] + + (Originally printed in Journal of Psychoactive Drugs, Vol 21(1), + Jan-Mar 1989). + + LSD and Creativity (reproduced w/o permission) + ------------------ + + Oscar Janiger, M.D. (Department of Psychiatry, University of + California, Irvine, California) + + Marlene Dobkin de Rios, Pd. D. (Department of Anthropology, California + State University, Fullerton, California) + + CONCLUSION + + Contrary to popular belief, most artists find it possible to exercise + some technical proficiency, with varying degrees of success, under the + influence of LSD. This seems to improve with repeated experiences. The + artistic productions are not ipso facto inferior to those performed in + ordinary states of consciousness. However, in evaluating the reports + and follow-up questionnaires, they are often judged by the artists to + be more interesting or even aesthetically superior to their usual mode + of expression. A review of the follow-up information shows that, in + many instances, the artist in the series described herein felt that + the LSD experience pruduced some desirable lasting change in their + understanding of their work, which continued to incluence the form and + direction of their artistic development. A so-called confusional or + disorganized phase may represent a creative crisis in which the artis + struggling, to maintain his/her traditional approach, finally reaches + another level of integration and expression. + + These metamorphoses all contribute to the artists' convictions that + they are able to create new meanings in an emergent world. It is of + special interest to note that many of those elements that are + universally reported under the influence of LSD are those features + traditionally associated with heightened artistic creativity. The + ultiamte explanation for these changes may lie in a biochemical basis + of perception and/or the cultural history of the individual. + + **************************** Article Separation ******************************* + + I was reading a back copy of The Journal of Drug Issues looking at an article + on additiction when I came accross annother article. A chemistry for world + peace. Willam H. McGlothlin, Journal of Drug Issues, Spring 1985, 225-245. + + Ok so it is a twinkie title, however it is perhaps the best article I have ever + read on acid. The abstract; + + This paper presents an argument for research into + the means of altering individual attitudes, values, + and communication abilities in the direction of + increased social empathy, which , inturn would + produce a more favorable enviroment for resolving + differences and facilitate peaceful negotions + between individuals and nations. It is proposed + that prior research with the drug d-lysergic acid + diethylamide (LSD), shows sufficient promise in + producing relatively long-lasting changes in the + above areas to merit further research. Furthermore, + the use of LSD has been demonstrated to be quite + safe _under supervisory conditions_, i.e. the + guided "trip." LSD is also non-toxic and + non-addictive. + A brief history of psychedelic drugs is + provided along with a description of thier + psychological effects. Some possible modes of + action are discussed. LSD and other psychedelics + are seen as a possible means of tapping mental + resources which are not ordinarily available, but + which may be of great value to the individual and + ultimately to the society. + + The man who wrote it is unfortunantly dead, he was a well recognized scholar + with a number of awards from academia and the government. He worked for RAND + for a number of years and was no brainless yammerhead (despite the twinkie + title). + + The article is full of all kinds of interesting things, A very good brief + history of LSD and other psychedelics, one of the dest descriptions of an LSD + experience I have ever encountered here is part: + + About 30 minutes after ingesting LSD the + subject normally experiences a feeling of dizziness + or intoxication. One of the most common early + emotional reactions is smiling and laughing, which + sometimes develops into uncontrollable laughing + and/or crying. With closed eyes there is a + lightening of the normal gray-black expanse and + almost invariably colorful and luminous geometric + designs appear in the field of vision. They may + change into architechtural structures which + freaquently are in very saturated colors and appear + to be glowing from an internal light. + + He goes on to discuss changes resulting from the LSD experience (almost all are + beneficial), and then talks about side effects. One nifty factoid; + + Estimated rates of Major Complications Associated with LSD + + Attempted completed psychotic reaction + suicide suicide over 48 hours + + experimental + subjects- 0/1000 0/1000 0.8/1000 + + patients + undergoing + therapy- 1.2/1000 0.4/1000 1.8/1000 + + (w/o psychobabble that means like really fucking good) + + + There are also three and a half pages of cited references which alone is worth + diggin up the article. + + **************************** Article Separation **************************** + + Newsgroups: alt.drugs + Distribution: world + Subject: From the Merck Manual -- LSD references, etc + Keywords: LSD, Lysergic Acid Amide, Lysergic Acid + Summary: A couple of pages of copywrite infringement + + From the 11th Edition of the Merck manual, the "Centennial Edition" no less: + [perhaps something to drop in the FAQ?] + + 5505. Lysergamide. 9,10-Didehydro-6-methylergoline- + 8beta-carboxamide; lysergic acid amide; ergine. C16H17N3O; + mol wt 267.32. C 71.88%, H 6.41%, N 15.72%, O 5.99%. + Isoln from _Rivea_corymbosa_(L.) and from _Ipomoea_tricolor_ + Cav., _Convolvulaceae_: Hofmann, Tscherter, _Experientia_ 16, + 414 (1964). Prepn from lysergic acid hydrazide: Ainsworth, + U.S. pat. 2,756,235 (1956 to Lilly); from lysergic acid and + phosgene-dimethylformamide complex: Patelli, Bernardi, + U.S. pat. 3,141,887 (1964 to Farmitalia). Microbiological + production: Rutschmann, Kobel, U.S. pat. 3,219,545 (1965 + to Sandoz). + + H. CONH2 + '. / + / \ + / \ + || | + || N + /\\ /\ / \ + / \\ / \ / CH3 + || | | \ + || | | H + \ // \ / + \// \/ + | || + | || + HN------- + + Prisms from methanol. dec 242deg. [alpha](5461)(20) + 15% (c = 0.5 in + pyridine). + Methanesulfonate, C7H21N3O4S, prisms from methanol + + acetone, dec 232deg. + Note: This is a controlled substance (depressant) listed in + the U.S. code of Federal Regulations, Title 21 Part 1308.13 + (1987). + + 5506. Lysergic Acid. 9,10-Didehydro-6-methylergoline- + 8-carboxylic acid. C16H16N2O2; mol wt 268.32. C 71.62%, + H 6.01%, N 10.44%, O 11.93!. Ayseqgic acid and isolyser- + gic acid are the main cleavage products formed on alkaline + hydrolysis of the alkaloids which are characteristic of ergot. + Jacobs, Craig et al., _J._Biol._Chem._ 104, 547 (1934); 125, 289 + (1938); 130, 399 (1939); 145, 487 (1942); _J._Org._Chem._ 10, + 76 (1945). High-yield production by _Claviceps_paspali_: + Arcamone et al., _Proc._Roy._Soc._ (London), _Ser._B_, 155, 26 + (1961). total synthesis: Kornfeld et al., _J._Am._Chem._Soc._ + 76, 5256 (1954); 78, 3087 (1956); M. Julia et al., _Tetrahedron_ + _letters_ 1969, 1569; V.W. Armstrong et al., ibid. 1976, 4311; + W. Oppolzer et al., _Helv._Chem._Acta_ 64, 478 (1981); R. + Ramage et al., _Tetrahedron_ 37, Suppl. 9, 157 (1981); J. + Rebek, D.F. Tai, _Tetrahedron_Letters_ 24, 859 (1983). Ste- + reochemistry: Stoll et al., _Helv._Chem._Acta 37, 2039 (1954); + Stenlake, _J._Chem._Soc._ 1955, 1626; Leeman, Fabbri, _Helv._ + _Chim._Acta_ 42, 2696 (1959). Absolute configuration: Stad- + ler, Hoffman, ibid. 45, 2005 (1962). + + H. COOH + '. / + / \ + / \ + || | + || N + /\\ /\ / \ + / \\ / \ / CH3 + || | | \ + || | | H + \ // \ / + \// \/ + | || + | || + HN------- + + Haxagonal scales, plates with one or two moles H20 from + water, mp 240deg (dec). [alpha](D)(20) + 40deg (c = 0.5 in pyridine). + Behaves as an acid and base, pKa 3.44, pKb 7.68. Moder- + ately sol in pyridine. Sparingly sol in water and in neutral + organic solvents; sol in NaOH, NH4OH, Na2CO3, and HCL + solns. Slighly sol in dil H2SO4. + Methyl ester, thin leaflets from benzene, mp 168deg. + Note: This is a controlled substance (depressant) listed in + the U.S. code of Federal Regulations, title 21 Part 1308.13 + (1987). + + 5507. Lysergide. 9,10-Didehydro-N,N-diethyl-6-meth- + ylergoline-8beta-carboxamide; N,N-diethyl-D-lysergamide; D- + lysergic acid diethylamide; LSD; LSD-25; Lysergsaure Di- + ethylamid. C20H25N3O; mol wt 323.42. C 74.27%, H 7.79%, + N 12.99%, O 4.95%. Microbal formation by _Claviceps_pas- + pali_ over the hydroxyethylamide; Arcamone et al., _Proc._ + Roy._Soc._(London) 155B, 26 (1961). Partial synthesis: Stoll, + Hofmann, _Helv._Chim._Acta_ 26, 944 (1943); 38, 421 (1955). + Industrial prepn: Pioch; Garbrecht, U.S. pats. 2,736,728; + 2,774,763 (both 1956 to Lilly); Patelli, Bernardi, U.S. pat. + 3,141,887 (1964 to Farmitalia). Isotope-labeled LSD: Stoll + et al., _Helv._Chim._Acta_ 37, 820 (1954). Toxicity data: E. + Rothlin, _Ann._N.Y._Acad._Sci._ 66, 668 (1957). Review: Hof- + fer, _Clin._Pharmacol._Ther._ 6, 183 (1965). Book: _The_Use_of_ + LSD_in_Psychotherapy_and_Alcoholism_, H.A. Abramson, Ed. + (Bobbs-Merrill, Indianapolis, 1967) 697 pp. + + / C2H5 + H. CON + '. / \ C2H5 + / \ + / \ + || | + || N + /\\ /\ / \ + / \\ / \ / CH3 + || | | \ + || | | H + \ // \ / + \// \/ + | || + | || + HN------- + + Pointed prisms from benzene, mp 80-85 degs. [alpha](D)(20) + 17deg (c = + 0.5 in pyridine). uv max (ethanol): 311 nm (E(1 cm)(1%) 257). + LD50 in mice, rats, rabbits (mg/kg): 46, 16.5, 0.3 i.v. + (Rothlin). + D-Tartrate, C46H64N6O10, solvated, elongated prisoms from + methanol, mp 198-200deg. [alpha](D)(20) + 30 deg. Soluble in water. + Caution: This is a controlled substance (hallucinogen) + listed in the U.S. Code of Federal Regulations, Title 21 Part + 1308.11 (1987). + USE: In biochemical research as an antagonist to serotonin. + Has been used experimentally as adjunct in study and treat- + ment of mental disorders. + + NOTES: Not guaranteed to be free from typos. + Underlines are supposed to be italic (ie book/journal titles, etc) + Alpha, beta, and deg are the greek letters and the degree symbol + [alpha](D)(20) means a greek letter in [] followed by a subscript + and then a superscript (I don't know *WHAT* this actually is) + The chemical structures are almost exactly what the Merck manual has + drawn. Almost nothing was lost in the conversion to ASCII. + [if you wanted to get really technical, the lower hydrogen atom in + all of the structures should be coming out, and have a thick line] + +============================================================================= + +In article <1992Dec8.093008.25698@gdunix.gd.chalmers.se> guccw@gdunix.gd.chalmers.se (Christian Wernstedt) writes: +> +> Has anyone any comments on this? Is it common that people experiencing +>a bad trip resort to violence against him/herselves or people around? Any +>anecdotes, statistical info or just scientific references would be of +>benefit to get a clearer picture. +> + +A followup to my earlier reply. Two refrences from the bibliograpy +of Intoxication, Ronald SIEGEL + +BARTER, J. T and REITE, M. 1969. +"Crime and LSD: The Insanity Plea." +American Journal of Psychiatry 126:113-19. + +REICH, R and HEPPS, R. B. 1972. +"Homicide During a Psychosis Induced by LSD." +Journal of American Medical Association 219:869-71 + +From Siegel's Intoxication (p 240): +The cases of Jeffery and Harold, who killed people after +having taken LSD, are presented. + + "Cases like Harold's tend to confuse the issue of intoxication + and violence. Violent people are often intoxicated but the + violence is usually rooted in the personality, not the drug." + +mark + + + diff --git a/textfiles.com/drugs/lsddat.drg b/textfiles.com/drugs/lsddat.drg new file mode 100644 index 00000000..201e3b4d --- /dev/null +++ b/textfiles.com/drugs/lsddat.drg @@ -0,0 +1,514 @@ +1972 tablet LSD pink tablet +1972 tablet LSD bright orange pellet; street name "sunshine" +1972 tablet LSD white tablet aspirin size +1972 tablet LSD white tablet aspirin size +1972 tablet LSD,PCP light blue tablet +1972 tablet LSD (450ug) red saccharin size tablet--"sunshine" +1972 tape LSD "clearlight"--drug between scotch tape +1972 tape LSD (impure) "clearlight"--drug between scotch tape +1972 tape LSD "clearlight"--drug between scotch tape +1972 tablet LSD "whitelight"--white tablet +1972 tablet LSD (impure) "orange sunshine"--bright orange tablet +1972 tablet LSD "orange sunshine"--bright orange tablet +1972 tablet LSD (125ug) small yellow tablet +1972 tablet LSD (impure) purple tablet +1972 tablet LSD red-orange saccharin size tablet +1972 tablet LSD orange saccharin size tablet +1972 tablet LSD small purple "bead" +1972 tablet LSD (475ug) orange saccharin size tablet +1972 tablet LSD orange saccharin size tablet ("Sunshine") +1972 powder LSD bright orange powder +1972 tablet LSD orange saccharin size tablet +1972 tablet LSD (225ug) dark red tablet ("Rose Sunshine") +1972 tablet LSD orange tablet, crushed ("Orange Sunshine") +1972 tablet LSD red-orange tablet, crushed ("Sunshine") +1972 tablet LSD,PCP pale green tablet, ("Greenies") +1972 gelatin LSD clear gelatin squares, 1.5mmx1.5mm "Clearlight" +1972 tablet LSD green tablet, 62 mg. "Berkeley Green" +1972 paper LSD blotter paper with gray spot, (3mm diameter) +1972 powder LSD white powder +1972 paper LSD paper with gray green spot +1972 capsule LSD clear capsule 7mm x 21mm +1972 - LSD - +1972 tablet LSD yellow tablet, 5mm x 3mm; 58 mg. +1972 powder LSD orange grains "Sunshine LSD" +1972 tablet LSD green tablet, crushed +1972 tablet LSD white tablet, 6.5mm(dia.)x3.0mm(thick), 125mg. +1972 gelatin LSD clear wafers: 1.0mmx2.5mm, 1mg."windowpane" +1972 gelatin LSD gelatin layer, 2.8mm x 2.2mm, 1.1mg. +1972 tablet LSD blue cyl. tablet, 55mg. "Blue Sunshine" +1972 tablet LSD red tablet, crushed +1972 tablet LSD,PCP green tablet, 3mmx1.5mm "Greenies Acid" +1972 paper LSD blotter paper with gray spot 3/4" dia. +1972 tablet LSD purple tablet crushed +1972 tablet LSD small purple tablet 3mmx2mm, 17mg. +1972 tape LSD thin plastic-like sq. 2mmx2mm, 0.5mg. +1972 capsule LSD brown powder in large capsule, 24mmx9mm. +1972 gelatin LSD small clear square 1/16" x 1/16" +1972 tablet LSD yellow tablet 6mmx3mm, 75 mg. +1972 capsule LSD brown powder in clear capsule, 24mmx9mm +1972 capsule LSD brown powder in green capsule, 7mmx9mm +1972 powder LSD powder--no description +1972 tablet LSD purple tablet with white specks +1972 tablet LSD green-rust speckled double dome tablet +1972 tablet LSD bright yellow saccharin tablet, 100 mg. +1972 powder LSD turquoise specks +1972 powder LSD white powder +1972 tablet LSD yellow tablet +1972 powder LSD turquoise powder +1972 tablet LSD blue tablet 1/4" dia. x 1/8" +1972 powder LSD white powder +1972 powder LSD cream colored powder +1972 powder LSD orange powder +1972 tablet LSD white tablet 3/10" x 1/8" +1972 tablet LSD blue tablet 1/4" x 9/32" +1972 powder LSD white powder +1972 tablet LSD orange tablet +1972 tablet LSD light green tablet 5/32" x 3/32" +1972 tablet LSD red tablet 3/10" x 1/8" +1972 gelatin LSD small brown gelatin square +1972 tablet LSD (impure) blue tablet 3/16" x 1/8" +1972 tablet LSD (impure) white tablet 3/10" x 3/32" +1972 powder LSD white powder-white window pane acid +1972 tablet LSD,PCP tan colored tablets +1972 capsule LSD,Amphet light brown powder in clear capsule +1972 powder No Drug Present orange brown powder +1973 tablet LSD orange tablet +1973 capsule LSD white powder in clear capsule +1973 powder LSD orange powder +1973 gelatin LSD chocolate brown window pane +1973 tablet LSD purple tablet +1973 powder LSD orange powder +1973 paper LSD green spots on blotter paper +1973 tablet LSD small pink and yellow tablet +1973 liquid LSD liquid in murine bottle +1973 tablet LSD tan tablet +1973 powder LSD pink powder +1973 powder LSD turquoise powder +1973 powder LSD cream powder +1973 tablet LSD pale pink domed tablet, 1/8" diameter +1973 tablet LSD pale yellow tablet +1973 tablet LSD purple tablet 3/8" diam. +1973 paper LSD blotter paper +1973 tablet LSD pink speckled tablet +1973 powder LSD pink powder +1973 tablet LSD pink tablet +1973 tablet LSD purple tablet +1973 tablet LSD orange tablet +1973 tablet LSD pink tablet 1/8" diam. +1973 tablet LSD orange tablet 3/16" diam. +1973 tablet LSD raspberry tablet 1/4" diam. +1973 tablet LSD green tablet +1973 tablet LSD orange tablet +1973 sugar LSD blue & pink spotted sugar cube +1973 tablet LSD yellow tablet 5/32" diam. +1973 tablet LSD blue tablet 1/4" diam. +1973 tablet LSD blue tablet 1/4" diam. +1973 tablet LSD yellow tablet 5/32" diam. +1973 capsule LSD white powder in clear capsule +1973 tablet LSD white tablet 7/32" diam. +1973 tablet LSD light purple tablet 3/16" diam. +1973 tablet LSD yellow tablet 1/4" diam. +1973 capsule LSD white powder in clear capsule +1973 tablet LSD red tablet 3/16" diam. +1973 tablet LSD white tablet 3/16" diam. +1973 tablet LSD purple tablet 1/4" diam. +1973 tablet LSD yellow tablet 3/16" diam. +1973 tablet LSD blue tablet 1/4" diam. +1973 tablet LSD yellow tablet 5/32" diam. +1973 tablet LSD,MA pink tablet +1973 tablet LSD,MA purple tablet 1/4" diam. +1973 paper LSD,PCP square white blotter paper +1973 liquid ergot alkaloids extract of morning glory seeds +1973 powder PCP white powder +1973 liquid No Drug Present liquid in cola can +1973 powder LSD white powder +1973 tablet LSD yellow tablet, 3/16" diam. +1973 tablet LSD orange tablet, 3/16" diam. +1973 tablet LSD green tablet, 5/32" diam. +1973 tablet LSD red tablet, 5/32" diam. +1973 gelatin LSD clear windowpane, 1/8" x 1/8" +1973 tablet LSD red tablet, 3/16" diam. +1973 paper LSD green spot on blotting paper +1973 gelatin LSD clear windowpane, 1/8" x 1/8" +1973 tablet LSD pink tablet, 5/32" diam. x 1/16" thick +1973 tablet LSD green tablet, 5/32" diam. x 1/16" thick +1973 tablet LSD white tablet, 5/32" diam. x 1/16" thick +1973 tablet LSD orange tablet, 5/32" diam. x 3/32" thick +1973 powder LSD white powder +1973 tablet LSD orange tablet, 3/32" thick +1973 paper LSD brown spot on blotting paper +1973 tablet LSD white tablet, 3/16" diam. x 1/8" thick +1973 tablet LSD pale yellow tablet, 1/4" diam. x 1/8" thick +1973 gelatin LSD clear windowpane, 1/8" x 1/8" +1973 gelatin LSD clear windowpane, 1/8" x 1/8" +1973 tablet LSD dark grey tablet +1973 tablet LSD pink tablet, 3/16" diam. x 3/32" thick +1973 tablet LSD yellow tablet, 5/32" diam. x 1/16" thick +1973 gelatin LSD clear windowpane 1/8" x 1/8" +1973 tablet LSD yellow tablet, 5/16" diam. x 1/8" thick +1973 tablet STP purple tablet, 3/16" diam. +1973 tablet LSD yellow tablet, 1/4" diam. x 1/8" thick +1973 paper LSD green paper toweling, 1 7/16" x 1" +1973 powder LSD orange powder +1973 tablet LSD orange tablet, 5/32" diam. x 3/32" thick +1973 tablet LSD (90ug) white tablet, 5/32" diam. x 3/32" thick +1973 paper LSD green spot on blotter paper +1973 gelatin LSD clear windowpane, 1/4" x 5/32" +1973 paper LSD (50ug) spot on blotter paper +1973 paper LSD (60ug) spot on blotter paper +1973 gelatin LSD clear windowpane, 1/4" x 5/32" +1973 tablet LSD (60ug) purple tablet, 1/4" diam. x 1/8" thick +1973 capsule LSD (55ug) gray powder in clear capsule, 7/16" x 3/16" +1973 tablet LSD (55ug) white tablet, 1/4" diam. x 3/16" thick +1973 tablet LSD blue tablet, 3/16" diam. x 1/8" thick +1973 tablet LSD white tablet, 3/16" diam. x 1/8" thick +1973 capsule LSD orange-brown powder in clear capsule +1973 tablet LSD (100ug) purple tablet, 1/4" diam. x 1/16" thick +1973 tablet LSD blue tablet, 3/16" diam. x 3/32" thick +1973 paper LSD blotter paper with "Mr. Natural" stamp +1973 tablet LSD (50ug) pink tablet, 3/16" diam. x 3/32" thick +1973 tablet LSD (190ug) red-orange barrel, 5/32" diam. x 1/8" thick +1973 tablet LSD (60ug) pink tablet, 1/4" diam. x 1/8" thick +1973 tablet LSD (65ug) yellow tablet, 3/16" diam. x 1/8" thick +1973 tablet LSD yellow tablet, 3/16" diam. x 3/32" thick +1973 paper LSD blotter paper, 1/4" x 1/4" +1973 tablet LSD turqouise tablet +1973 liquid LSD (110ug) two drops clear liquid +1973 tablet LSD red tablet, 1/4" diam. x 1/8" thick +1973 paper LSD blue blotter paper, 1 1/4" x 3/4" +1973 paper LSD blue spot on white blotter paper +1973 paper LSD light brown spot on white blotter paper +1973 paper STP brown spot on blotter paper +1973 tablet LSD red tablet, 3/16" diam. x 1/8" +1973 gelatin LSD (40ug) clear "windowpane", 3/32" x 3/32" +1973 tablet LSD white tablet, 3/16" diam. x 1/8" +1973 paper LSD (90ug) blue spot on white blotter "Love Saves" +1973 tablet LSD (55ug) light brown tablet, 1/4" diam x 1/8" +1973 gelatin LSD (50ug) clear "windowpane", 1/8" x 1/8" +1973 tablet LSD orange tablet, "Sunshine" +1973 gelatin LSD (120ug) clear "windowpane", 1/8" x 1/8" +1973 powder LSD white powder +1973 tablet LSD (30ug) pale violet tablet, 1/4" diam. x 1/8" +1973 paper LSD yellow spot on white paper +1973 tablet LSD purple tablet, 1/4" diam. x 1/16" +1973 tablet LSD light green tablet +1973 paper LSD white blotter paper +1973 tablet LSD orange tablet +1973 paper LSD white blotter paper +1973 tablet LSD (100ug) purple tablet, 1/4" diam. x 1/16" +1973 paper LSD beige spots on white blotter paper +1973 tablet LSD violet tablet, 3/16" diam. x 3/32" +1973 paper LSD (60ug) spot on blotter paper +1973 tablet LSD yellow tablet, 3/16" diam. x 1/16" +1973 paper LSD (80ug) pink spot on white blotter paper +1973 tablet LSD (75ug) orange tablet, 3/16" diam. x 1/8" +1973 tablet LSD orange tablet, 3/16" diam. x 3/32" +1973 paper LSD (50ug) white blotter paper with colored design +1973 liquid LSD (55ug/drop) clear liquid +1973 tablet LSD (190ug) gray tablet, 3/16" diam x 3/32" +1973 tablet LSD (50ug) violet tablet, 3/16" diam. x 1/8" +1973 tablet LSD (120ug) orange barrel,5/32"diam.x1/8" "Orange Sunshine" +1973 tablet LSD red tablet, 3/16" diam. x 3/32" +1973 tablet LSD brown tablet, 3/16" diam. x 1/8" +1973 paper LSD (140ug) spot on white blotter paper +1973 tablet LSD (100ug) scored white tablet, 9/32" diam. x 1/16" +1973 tablet LSD (65ug) pale pink tablet, 3/16" diam. x 5/64" +1973 tablet LSD (80ug) white microtablet, 3/32" diam. x 1/16" +1973 tablet LSD red tablet, 1/4" diam. x 1/8" +1973 paper LSD white blotter paper with colored design +1973 tablet LSD white tablet, 1/4" diam. x 1/16" +1973 tablet LSD white tablet, 3/16" diam. x 1/8" +1973 tablet LSD (20ug) pale orange tablet, 3/16" diam. x 1/8" +1973 tablet LSD (85ug) yellow tablet, 3/16" diam. x 3/32" +1973 paper LSD (100ug) red blotter -- star design+Sanskrit inscription +1973 tablet LSD pale orange tablet, 1/4" diam. x 1/8" +1973 powder LSD pale yellow crystalline material +1973 tablet LSD (50ug) white tablet, 3/16" diam. x 1/8" +1973 tablet LSD white tablet, 1/4" diam. x 1/16" +1973 gelatin LSD (100ug) clear "windowpane", 1/8" x 1/8" +1973 tablet psuedoephedrine scored white tablet (also contains triprolidine) +1973 powder No Drug Present white powder +1973 tablet No Drug Present biege tablet, 3/16" diam. x 1/8" +1973 tablet LSD white tablet, 3/32" diam. x 1/16" +1973 tablet LSD,iso-LSD purple tablet (80ug LSD/40ug iso-LSD) +1973 tablet LSD (80ug) green-yellow tablet, 1/8" diam. x 1/16" +1973 tablet LSD (55ug) white tablet, 3/16" diam. x 1/8" +1973 paper LSD white blotter paper "Love Saves" +1973 tablet LSD (70ug) white microtablet, 3/32" diam. x 1/16" +1973 gelatin LSD clear "windowpane", 3/32" x 3/32" +1973 gelatin LSD red "windowpane", 3/32" x 3/32" +1973 tablet LSD violet tablet, 3/16" diam. x 3/32" +1973 tablet LSD violet tablet, 3/16" diam. x 3/32" +1973 paper LSD white paper with heart design and "Love Saves" +1973 tablet LSD (45ug) brown tablet, 1/4" diam. x 1/8" +1973 gelatin LSD (100ug) clear "windowpane", 3/32" x 3/32" +1973 powder LSD,iso-LSD 1 mg. white powder (500ug LSD/125ug iso-LSD) +1973 tablet LSD (40ug) rose tablet +1973 tablet LSD speckled yellow tablet, 3/16" diam. x 3/32" +1973 tablet LSD pale lime tablet, 3/16" diam. x 3/32" +1973 gelatin LSD (80ug) dark brown gelatin square, 1/8" x 1/8" +1973 gelatin LSD (100ug) clear gelatin square, 1/8" x 1/8" +1973 tablet LSD black speckled pale yellow tablet, 3/16"x3/32" +1973 tablet LSD lime tablet, 3/16" diam. x 7/64" +1973 tablet LSD blue tablet, 3/16" diam. x 3/32" +1973 capsule LSD yellow-brown powder in clear capsule +1973 tablet LSD orange tablet, 3/16" diam. x 1/8" +1973 tablet LSD,iso-LSD pale turquoise tablet (55ug LSD/15ug iso-LSD) +1973 paper LSD spot on white blotter paper +1973 tablet LSD white tablet, 1/4" diam. x 1/16" +1973 tablet LSD (40ug) orange tablet +1973 paper LSD,iso-LSD brown spot/white paper (105ug LSD/10ug iso-LSD) +1973 powder LSD white granular powder +1973 paper LSD brown spot/white paper (65ug LSD/30ug iso-LSD) +1973 paper LSD (110ug) spot on white blotter paper +1973 tablet LSD (60ug) orange tablet, 3/16" diam. x 1/8" +1973 tablet LSD (55ug) yellow tablet, 3/16" diam. x 1/8" +1973 paper LSD red spot on white blotter paper +1973 paper LSD,iso-LSD black design/white paper(35ug LSD/30ug iso-LSD) +1973 tablet LSD (55ug) white tablet, 3/16" diam. x 1/8" +1973 tablet LSD,iso-LSD orange tablet (50ug LSD/20ug iso-LSD) +1973 tablet LSD (50ug) yellow tablet, 1/4" diam. x 1/8" +1973 paper LSD (45ug) red and blue desing on white blotter paper +1973 tablet LSD (115ug) white tablet, 3/32" diam. x 1/16" +1973 tablet LSD (45ug) pale orange tablet, 3/16" diam. x 3/32" +1973 gelatin LSD clear gelatin square, 3/32" x 3/32" +1973 tablet LSD red tablet, 3/16" diam. x 1/8" +1973 paper LSD,iso-LSD pink spot/white paper (40ug LSD/10ug iso-LSD) +1973 gelatin LSD (80ug) brown gelatin square, 3/32" x 3/32" +1973 tablet LSD (50ug) pale yellow tablet, 1/4" diam. x 1/16" +1973 gelatin LSD blue gelatine rectangle, 1/8" x 1/16" +1973 tablet LSD,iso-LSD red tablet, broken (25ug LSD/20ug iso-LSD) +1973 tablet LSD (30ug) red tablet, 3/16" diam x 1/8" +1973 paper LSD blue spot/white paper/yellow Sanskrit inscrip. +1973 paper LSD (70ug) beige spot on white blotter paper +1973 tablet LSD (50ug) dark grey tablet, 3/16" diam. x 3/32" +1973 tablet LSD lemon yellow tablet, 3/16" diam. x 1/8" +1973 gelatin LSD clear gelatin square, 1/8" x 1/8" +1973 tablet LSD brown tablet, 1/4" diam. x 1/16" +1973 tablet LSD (50ug) white tablet, broken +1973 tablet LSD (75ug) yellow tablet, 3/16" diam. x 1/8" +1973 tablet LSD,iso-LSD red tablet (30ug LSD/10ug iso-LSD) +1973 paper LSD turquoise spot/white paper/red+blue design +1973 tablet LSD,iso-LSD white tablet (45ug LSD/15ug iso-LSD) +1973 paper LSD,iso-LSD beige spot/white paper (120ug LSD/40ug iso-LSD) +1973 tablet LSD,iso-LSD red tablet, 1/4" diam. x 3/16" +1973 tablet LSD violet tablet, 3/16" diam. x 3/32" +1973 gelatin LSD amber gelatin square, 3/32" x 3/32" +1973 gelatin LSD (100ug) amber gelatin square, 3/32" x 3/32" +1973 tablet LSD (90ug) red tablet, 1/4" diam. x 1/8" +1973 powder LSD beige powder (105ug/100mg) +1973 tablet LSD (45ug) white tablet, 3/32" diam. x 1/16" +1973 powder Amphet white powder +1973 capsule chlorpromazine white powder in yellow capsule +1973 tablet STP beige tablet, 3/16" diam. x 1/8" +1973 gelatin No Drug Present clear gelatin square, 1/16" x 1/16" +1973 tablet No Drug Present rust orange tablet, 1/4" diam. x 1/8" +1973 tablet No Drug Present white tablet, 7/32" diam. x 1/8" +1973 tablet No Drug Present pink tablet, 7/32" diam. x 3/32" +1973 gelatin No Drug Present clear gelatin square, 1/8" x 1/8" +1973 gelatin LSD amber gelatin square, 3/32" x 3/32" +1973 gelatin LSD amber gelatin square, 3/32" x 3/32" +1973 tablet LSD red tablet, 3/16" diam. x 1/8" +1973 tablet LSD,iso-LSD white tablet (45ug LSD/5ug iso-LSD) +1973 tablet LSD (45ug) white tablet, 1/4" diam x 5/32" +1973 paper LSD lime spot/white paper/red+blue design +1973 gelatin LSD amber gelatin square +1973 tablet LSD yellow tablet, broken +1973 gelatin LSD (65ug) purple gelatin square, 5/32" x 5/32" +1973 tablet LSD,iso-LSD violet tablet (30ug LSD/8ug iso-LSD) +1973 paper LSD (20ug) brown spot on white blotter paper +1973 tablet LSD violet tablet, 3/16" diam. x 1/8" +1973 tablet LSD (35ug) pale orange tablet, 3/16" diam. x 1/8" +1973 powder LSD,iso-LSD gray crystalline powder +1973 gelatin LSD dark brown gelatin square, 3/32" x 3/32" +1973 gelatin LSD (125ug) clear gelatin square, 3/32" x 3/32" +1973 tablet LSD (40ug) burgandy tablet, 3/16" diam. x 1/8" +1973 tablet LSD turquoise tablet, 1/4" diam. x 1/8" +1973 gelatin LSD clear amber gelatin square, 3/32" x 3/32" +1973 tablet LSD yellow tablet, 3/16" diam. x 3/32" +1973 tablet LSD blue tablet, 3/16" diam. x 3/32" +1973 liquid LSD (75ug/drop) clear liquid +1973 gelatin LSD (50ug) clear turquoise gelatin square, 1/8" x 1/8" +1973 tablet LSD (30ug) green tablet, 1/4" diam. x 1/16" +1973 tablet LSD yellow tablet, 5/16" diam. x 1/8" +1973 tablet LSD white tablet, 1/4" diam. x 3/16" +1973 tablet LSD (35ug) yellow tablet, 3/16" diam. x 1/8" +1973 tablet LSD (70ug) green tablet, 3/16" diam. x 1/8" +1973 tablet LSD (65ug) blue tablet, 3/16" diam. x 1/8" +1973 tablet LSD (65ug) orange tablet, 3/16" diam. x 3/32" +1973 capsule PCP (trace) rust-brown powder in clear capsule +1973 tablet LSD (70ug) white tablet, 3/32" diam. x 1/16" +1973 tablet LSD (70ug) white tablet, broken +1973 tablet LSD (40ug) red tablet, 7/32" diam. x 1/8" +1973 tablet LSD blue tablet, 3/16" diam. x 1/8" +1973 sugar LSD sugar cube +1973 gelatin LSD amber gelatin square, 3/32" x 1/8" +1973 tablet LSD grey-green tablet, 3/32" diam. x 1/16" +1973 paper LSD (100ug) white blotter paper with black design +1973 tablet LSD (70ug) grey-green tablet, 3/16" diam. x 3/32" +1973 tablet LSD yellow tablet, 3/16" diam x 3/32" +1973 paper LSD (60ug) white blotter paper +1973 paper LSD (35ug) white blotter paper +1973 tablet LSD (100ug) violet tablet, 5/32" diam. x 1/16" +1973 tablet LSD (90ug) violet tablet, 3/16" diam. x 3/32" +1973 tablet LSD blue tablet, broken +1973 gelatin LSD clear amber gelatin square, 3/32" x 3/32" +1973 tablet LSD violet tablet, 3/16" diam. x 1/8" +1973 tablet LSD (320ug) yellow & day-glo pink tablet, 5/32" x 1/16" +1973 tablet LSD (140ug) purple tablet, 3/16" diam. x 1/16" +1973 gelatin LSD green gelatin square, 1/4" x 1/4" +1973 gelatin LSD amber gelatin square, 3/32" x 3/32" +1973 paper LSD white blotter paper, 7/8" x 7/8" +1973 gelatin LSD (140ug) amber gelatin square, 3/32" x 3/32" +1973 gelatin LSD (145ug) amber gelatin square, 3/32" x 3/32" +1973 gelatin LSD (180ug) amber gelatin square, 3/32" x 3/32" +1973 paper LSD (10ug) spot on white blotter paper +1973 tablet LSD white tablet, 3/32" diam. x 1/16" +1973 tablet LSD (85ug) yellow-green tablet, 3/32" diam. x 1/16" +1973 gelatin LSD clear amber gelatin square +1973 tablet LSD (80ug) grey-green tablet, broken +1973 paper LSD (10ug) spot on white blotter paper +1973 tablet LSD yellow tablet, broken +1973 paper LSD "Mr. Natural" blotter paper +1973 liquid LSD (55ug/drop) clear liquid +1973 tablet LSD (80ug) white double-dome tablet, 1/4" diam. x 5/32" +1973 powder LSD lavender powder +1973 tablet LSD (85ug) violet tablet, 3/16" diam. x 1/8" +1973 tablet LSD brown tablet, 1/4" diam. x 1/16" +1973 gelatin LSD clear amber gelatin square, 3/32" x 3/32" +1973 gelatin LSD (95ug) clear amber gelatin square, 3/32" x 3/32" +1973 tablet LSD (105ug) white tablet, 3/32" diam. x 1/16" +1973 tablet LSD (95ug) brown tablet, 5/16" diam. x 5/32" +1973 tablet LSD (60ug) violet tablet, 3/16" diam. x 3/32" +1973 tablet LSD (70ug) green tablet, 3/16" diam. x 3/32" +1973 tablet LSD (5ug) green tablet, broken +1973 gelatin LSD (190ug) amber gelatin square, 3/32" x 3/32" +1973 paper LSD (20ug) spot on orange blotter paper +1973 paper LSD (trace) manila paper rectangle +1973 gelatin LSD (120ug) amber gelatin square, 3/32" x 3/32" +1973 paper LSD (40ug) spot on octagonal white blotter paper +1973 tablet LSD (55ug) violet tablet, 3/16" diam. x 1/8" +1973 tablet LSD,iso-LSD red tablet (65ug LSD/10ug iso-LSD) +1973 tablet LSD red tablet, 3/16" diam. x 3/32" +1973 tablet LSD,iso-LSD yellow-green tablet (55ug LSD/10ug iso-LSD) +1973 tablet LSD yellow tablet, broken +1973 tablet LSD,iso-LSD brown & yellow table (70ug LSD/10ug iso-LSD) +1973 gelatin LSD amber galatin rectangle, 9/32" x 1/8" +1973 tablet LSD (65ug) magenta tablet, 3/16" diam x 1/8" +1973 tablet LSD (80ug) chartreuse tablet, 3/32" diam. x 1/16" +1973 tablet LSD (80ug) white tablet, broken +1973 tablet LSD,iso-LSD red tablet (60ug LSD/5ug iso-LSD) +1973 paper LSD,iso-LSD white "Mr. Natural" (90ug LSD/15ug iso-LSD) +1973 tablet LSD,iso-LSD chartreuse tablet, 3/32" diam. x 1/16" +1973 tablet LSD,iso-LSD red tablet, 3/16" diam. x 3/32" +1973 tablet LSD (215ug) orange barrel, 1/8" diam. x 1/8", "Sunshine" +1973 tablet LSD chartreuse tablet, 3/32" diam. x 1/16" +1973 sugar LSD sugar cube +1973 tablet LSD orange barrel, 5/32" diam. x 1/8" +1973 powder LSD white powder +1973 tablet LSD (15ug) pink tablet, broken +1973 tablet LSD,iso-LSD orange tablet (20ug LSD/10ug iso-LSD) +1973 tablet LSD,iso-LSD purple tablet (20ug LSD/5ug iso-LSD) +1973 tablet LSD (30ug) light purple tablet 3/16" diam. x 1/8" +1973 paper LSD (120ug) spot on white blotter paper +1973 paper LSD,iso-LSD white "Mr. Natural" (60ug LSD/25ug iso-LSD) +1973 gelatin LSD (110ug) amber gelatin square, 3/32" x 3/32" +1973 tablet LSD (60ug) lime tablet, 3/32" diam. x 1/16" +1973 tablet LSD yellow tablet, broken +1973 tablet LSD violet tablet, 3/16" diam. x 1/16" +1973 paper LSD (65ug) blue spot/white paper/red & blue design +1973 tablet LSD (55ug) lime tablet, 3/32" diam. x 1/16" +1973 gelatin LSD (115ug) amber gelatin square, 3/32" diam. x 1/16" +1973 tablet LSD (60ug) magenta tablet, 1/8" diam. x 1/16" +1973 tablet LSD,iso-LSD blue tablet (40ug LSD/30ug iso-LSD) +1973 tablet LSD,PCP lavender tablet 1/4" diam. x 1/8" (15ug LSD) +1973 tablet STP burgandy tablet, 3/16" diam. x 1/8" +1973 tablet STP dark grey tablet, 11/32" diam. x 1/8" +1973 tablet STP burgandy tablet, broken +1973 tablet STP beige tablet, 3/16" diam. x 1/8" +1973 gelatin No Drug Present clear gelatin rectange, 3/32" x 5/32" +1973 tablet No Drug Present white tablet, 1/4" diam. x 3/32" +1973 paper No Drug Present spot on yellow blotter paper +1973 tablet No Drug Present orange tablet, 7/32" diam. x 1/16" +1973 paper No Drug Present orange spot on white paper +1973 gelatin No Drug Present amber gelatin square, 3/32" x 3/32" +1973 tablet Amphet,PCP cross-scored white tablet, 1/4" diam. x 1/16" +1974 capsule LSD pale yellow powder in clear capsule 4/8"x9/32" +1974 capsule LSD,iso-LSD white powder in clear capsule 5/8" x 7/32" +1974 tablet LSD yellow tablet, 11/32" diam. x 1/8" +1974 paper LSD (40ug) white blotter paper +1974 tablet LSD yellow tablet, 3/16" diam. x 3/32" +1974 tablet LSD,iso-LSD yellow tablet (90ug LSD/10ug iso-LSD) +1974 powder LSD (60ug) yellow-green powder, "100ug" +1974 tablet LSD,iso-LSD "Blue Microdot" (55ug LSD/15ug iso-LSD) +1974 paper LSD,iso-LSD white blotter paper (140ug LSD/40ug iso-LSD) +1974 tablet LSD blue tablet, 3/32" diam. x 1/16" +1974 wax LSD deep violet waxy solid +1974 tablet LSD (65ug) white double-dome tablet, 1/4" diam x 3/16" +1974 paper LSD,iso-LSD "Mr. Natural" (55ug LSD/10ug iso-LSD) +1974 paper LSD (45ug) pink spot/white paper/red & blue design +1974 tablet LSD (55ug) orange tablet, 3/16" diam. x 3/32" +1974 tablet LSD (60ug) orange tablet, 3/16" diam. x 3/32" +1974 gelatin LSD (130ug) amber gelatin square, 3/32" x 3/32" +1974 tablet LSD pale yellow tablet, 1/4" diam. x 1/8" +1974 paper LSD,iso-LSD magenta on white paper (60ug LSD/20 iso-LSD) +1974 tablet LSD brick-red tablet, 1/4" diam. x 1/8" +1974 powder LSD white powder +1974 paper LSD,iso-LSD white blotter paper (100ug LSD/10ug iso-LSD) +1974 tablet LSD violet tablet, 3/16" x 3/32", "Purple Haze" +1974 paper LSD (55ug) yellow spot on white blotter paper +1974 tablet LSD (45ug) blue tablet, 3/32" diam. x 1/16" +1974 sugar LSD (60ug) sugar cube +1974 gelatin LSD amber gelatin square +1974 paper LSD,iso-LSD beige on white paper (80ug LSD/20ug iso-LSD) +1974 tablet LSD,iso-LSD orange tablet (55ug LSD/20ug iso-LSD) +1974 tablet LSD (60ug) white tablet, 3/32" diam. x 1/16" +1974 tablet LSD (65ug) violet tablet, 1/8" diam. x 1/16" +1974 paper LSD,iso-LSD white blotter paper (145ug LSD/20ug iso-LSD) +1974 paper LSD,iso-LSD white blotter paper (150ug LSD/20ug iso-LSD) +1974 paper LSD spot on white blotter paper +1974 tablet LSD violet tablet, 3/16" diam. x 3/32" +1974 powder LSD,iso-LSD orange powder (540ug LSD + 240ug iso-LSD/gm.) +1974 tablet LSD,iso-LSD turquoise tablet (70ug LSD/40ug iso-LSD) +1974 tablet LSD (105ug) white tablet, 3/16" diam. x 1/8" +1974 tablet LSD,iso-LSD rose tablet (40ug LSD/15ug iso-LSD) +1974 tablet LSD,iso-LSD blue tablet (30ug LSD/10ug iso-LSD) +1974 shroom LSD (20ug) brown mushroom cap with white gills +1974 shroom LSD (15ug) brown mushroom cap with white gills +1974 tablet LSD,iso-LSD,PCP brown tablet (95ug LSD/20ug iso-LSD/.34mg PCP) +1974 powder LSD,PCP pink powder (120ug LSD + 6.6mg PCP/gm.) +1974 tablet LSD,iso-LSD,PCP brown tablet (40ug LSD/20ug iso-LSD/80ug PCP) +1974 powder LSD,iso-LSD,STP grey pwd (.6mg LSD+120ug iso-LSD+trace STP/gm.) +1974 tablet LSD (55ug) yellow double-dome tablet, 3/16" diam. x 3/32" +1974 tablet LSD (50ug) yellow-green tablet, 3/32" diam x 1/16","100ug" +1974 tablet LSD,iso-LSD pale orange tablet (45ug LSD/5ug iso-LSD) +1974 tablet LSD pale yellow tablet, broken +1974 gelatin LSD amber gelatin square, 3/32" x 3/32" +1974 tablet LSD (55ug) blue tablet, 3/32" diam. x 1/16" +1974 tablet LSD (50ug) yellow tablet, 3/32" diam. x 1/16" +1974 tablet LSD violet tablet, 3/16" x 3/32","Purple Haze" +1974 gelatin LSD (75ug) violet gelatin square, 1/8" x 1/8" +1974 tablet LSD (100ug) violet tablet, 3/16" x 1/8", "500ug" +1974 tablet LSD violet domed tablet, 3/16" diam. x 1/8" +1974 tablet LSD,iso-LSD orange, "100ug" (45ug LSD/10ug iso-LSD) +1974 tablet LSD (75ug) orange tablet, 1/8" diam. x 3/32" +1974 tablet LSD (75ug) orange tablet, 3/16" diam. x 3/32" +1974 gelatin LSD amber gelatin square, 3/32" x 3/32" +1974 paper LSD,iso-LSD white blotter paper (95ug LSD/10ug iso-LSD) +1974 gelatin LSD (105ug) amber gelatin square, 3/32" x 3/32" +1974 tablet LSD (55ug) white double-dome tablet, 1/4" diam. x 5/32" +1974 tablet LSD (55ug) blue tablet, 3/32" diam. x 1/16" +1974 gelatin LSD (95ug) amber gelatin square, 3/32" x 3/32" +1974 tablet LSD (45ug) blue tablet, 3/32" diam. x 1/16" +1974 tablet LSD white tablet, 1/4" diam. x 1/16" +1974 paper LSD (105ug) white blotter paper +1974 tablet LSD (70ug) blue tablet, 3/32" diam. x 1/16" +1974 tablet LSD (65ug) blue tablet, 1/16" diam. x 1/32" +1974 tablet LSD (50ug) yellow tablet, 3/16" diam. x 3/32" +1974 tablet LSD (45ug) white tablet, 3/16" diam. x 1/8" +1974 liquid LSD clear liquid +1974 powder LSD white powder +1974 gelatin LSD amber gelatin square, 3/32" x 3/32" +1974 tablet LSD,PCP brown tablet (70ug LSD/.6mg PCP) +1974* tablet No Drug Present indigo barrel, 1/8" diam. x 3/32" diff --git a/textfiles.com/drugs/lsddosag.drg b/textfiles.com/drugs/lsddosag.drg new file mode 100644 index 00000000..3c6dc4b6 --- /dev/null +++ b/textfiles.com/drugs/lsddosag.drg @@ -0,0 +1,30 @@ +LSD Dosages +----------- + + The basic dosages of acid vary according to what kind of acid is +available and what medium of ingestion is used. Chemically the potency of +LSD-25 is measured in micrograms, or mics. If you're chemically minded or +making your own acid, then computing the number of mics is very important. +Usually between 300 to 500 micrograms (mics) is plenty for a five to eight +hour trip, depending on quality, of course. I have heard of people taking +as much as 1500 to 2000 mics. This not only extremely dangerous, it is also +wasteful. + LSD comes packaged in many different forms. The proverbial sugar +cube is pretty passe', in the sense that other more feasible methods have +taken its place. The most common are listed below. +[1> The brown spot, or a piece of paper with a dried drop of LSD on it, is + always around. Usually one spot equals one trip. +[2> Capsuled acid is extremely tricky, as the cap can be almost any color, + size, and potency. Always ask what the acid is cut with, as a lot + of acid is cut with either speed or strychnine. Also note dosage. +[3> Small white or colored tablets have been known to contain acid, but, + as with the capsuled acid, it is impossible to tell potency, without + asking. +[4> I have heard about some characters who attempted to shoot acid. Shooting + any drug is a bad scene. Stay away from it. I cannot imagine what + their rush was like, but would certainly advise against this form of + drug abuse. + + ************************************************ + + diff --git a/textfiles.com/drugs/lsdfaq.drg b/textfiles.com/drugs/lsdfaq.drg new file mode 100644 index 00000000..de92036d --- /dev/null +++ b/textfiles.com/drugs/lsdfaq.drg @@ -0,0 +1,1527 @@ +Hi, you're maintaining the ftp sites, yes? + +Here's the most recent L-faq, with some typos fixed, an extra quote +aded to theflashbacks section. + +Cheers, +DH + +-------------- +Editor: D. A. Honig (honig@ics.uci.edu) +Last Update: 21 Feb 92 +Subject: LSD + + FORMATTING INFO: +topic break: ****************************** +within-topic break: .............................. + +[This FAQ provided to reduce net bandwidth, as an informational resource only.] + +****************************** + + CONTENTS: + +LSD (definition, introduction) +Delysid (medical fact sheet for pharmaceutical LSD) (pharmacology) + + CAUTIONS, REAL AND IMAGINED +ADDICTION POTENTIAL (none) +ADULTERANTS (including the strychnine myth, manufacturing impurities, etc.) +BAD TRIPS (what they are, how to avoid, what to do) +MYTHS (stamps for children, staring at the sun..) +DANGERS (LSD isn't for morons...) +FLASHBACKS (what they are ---post-traumatic stress syndrome) +INSOMNIA (common, what to do) +TOLERANCE (aquired and lost quickly (3 days) harmlessly, no withdrawal) + + BACKROUND +ANTHROPOLOGY (and history) +BOTANY (sources in nature) +CHEMISTRY (structure) +MECHANISM OF ACTION (uncertain) +RELATED COMPOUNDS (psilocybin in mushrooms, ergot alkaloids in morning glories) +MANUFACTURE (forget it) + +DRUG TESTING (don't worry) +LEGAL SCHEDULING (sched. 1, no medical uses in US (despite past effective use)) + + PRAGMATICS +SET and SETTING (how to have a good time; lsd ain't beer) +STORAGE (keep in a cool dark dry place) +SYNERGIES, BAD COMBINATIONS (cannabis is good, otherwise be careful) + +REFERENCES & FURTHER READING + BEST: _Psychedelic Encyclopedia_ by Peter Stafford + _LSD: My Problem Child_ by Albert Hofmann + _ Licit & Illicit Drugs_ (Consumer Reports) + _Storming heaven : LSD and the American dream_ by Jay Stevens + +****************************** + + + +LSD + Generic name for the hallucinogen lysergic acid + diethylamide-25. Discovered by Dr. Albert Hofmann in 1938, LSD is one + of the most potent mind-altering chemicals known. A white, odorless + powder usually taken orally, its effects are highly variable and begin + within one hour and generally last 8-12 hours, gradually tapering off. + It has been used experimentally in the treatment of alcoholics and + psychiatric patients. [Where it showed some success.] It + significantly alters perception, mood, and + psychological processes, and can impair motor coordination and skills. + During the 1950s and early 1960s, LSD experimentation was legally + conducted by psychiatrists and others in the health and mental health + professions. Sometimes dramatic, unpleasant psychological reactions + occur, including panic, great confusion, and anxiety. Strongly + affected by SET and SETTING. Classification: hallucinogens. Slang + names: acid, sugar. See also appendix B. (RIS 27:211-52 entries) + + -- Research Issues 26, Guide to Drug Abuse Research Terminology, + available from NIDA or the GPO, page 54. + +.............................. + +Common Drug Slang Terms (NB: many of these refer to the carrier, ie, "Blotter" + or "Sugar Cubes". Often the local names will refer to patterns printed + on the blotter, eg, "Blue unicorn".): + + Acid, 'Cid, Sid, Bart Simpsons, Barrels, Tabs, Blotter, Heavenly blue, + "L", Liquid, Liquid A, Lucy in the sky with diamonds, Microdots, + Mind detergent, Orange cubes, Orange micro, Owsley, Hits, + Paper acid, Sacrament, Sandoz, Sugar, Sugar lumps, + Sunshine, Tabs, Ticket, Twenty-five, Wedding bells, Windowpane, + etc. + + + +.............................. + +from the data sheet accompanying product: +(see also Physician's Desk Reference from mid-60's) + + Delysid (LSD 25) + + D-lysergic acid diethylamide tartrate + + Sugar-coated tablets containing 0.025 mg. (25 ug.) + + Ampoules of 1 ml. containing 0.1 mg. (100 ug.) for oral +administration. + + The solution may also be injected s.c. or i.v. The +effect is identical with that of oral administration but +sets in more rapidly. + + PROPERTIES + + The administration of very small doses of Delysid +(1/2-2 ug./kg. body weight) results in transitory distur- +bances of affect, hallucinations, depersonalization, reliv- +ing of repressed memories, and mild neuro-vegetative symp- +toms. The effect sets in after 30 to 90 minutes and gen- +erally lasts 5 to 12 hours. However, intermittent distur- +bances of affect may occasionally persist for several days. + + METHOD OF ADMINISTRATION + + For oral administration the contents of 1 ampoule of +Delysid are diluted with distilled water, a 1% solution of +tartaric acid or halogen-free tap water. + + The absorption of the solution is somewhat more rapid +and more constant that that of the tablets. + + Ampoules which have not been opened, which have been +protected against light and stored in a cool place are +stable for an unlimited period. Ampoules which have been +opened or diluted solutions retain their effectiveness for 1 +to 2 days, if stored in a refrigerator. + + INDICATIONS AND DOSAGE + +a) Analytical psychotherapy, to elicit release of + repressed material and provide mental relaxation, par- + ticularly in anxiety states and obsessional neuroses. + The initial dose is 25 ug. (1/4 of an ampoule or 1 + tablet). This dose is increased at each treatment by + 25 ug. until the optimum dose (usually between 50 and + 200 ug.) is found. The individual treatments are best + given at intervals of one week. + +b) Experimental studies on the nature of psychoses: By + taking Delysid himself, the psychiatrist is able to + gain an insight in the world of ideas and sensations of + mental patients. Delysid can also be used to induced + model psychoses of short duration in normal subjects, + this facilitating studies on the pathogenesis of mental + disease. + + In normal subjects, doses of 25 to 75 ug. are generally + sufficient to produce a hallucinatory psychosis (on an + average 1 ug./kg. body weight). In certain forms of + psychosis and in chronic alcoholism, higher doses are + necessary (2 to 4 ug./kg. body weight). + + PRECAUTIONS + + Pathological mental conditions may be intensified by +Delysid. Particular caution is necessary in subjects with a +suicidal tendency and in those cases where a psychotic +development appears imminent. The psycho-affective lability +and the tendency to commit impulsive acts may occasionally +last for some days. + + Delysid should only be administered under strict medi- +cal supervision. The supervision should not be discontinued +until the effects of the drug have completely worn off. + + ANTIDOTE + + The mental effects of Delysid can be rapidly reversed +by the i.m. administration of 50 mg. chlorpromazine. + + Literature available on request. + + SANDOZ LTD., BASLE, SWITZERLAND + +9792*-Z1540 e.-sp./d.-fr. +Printed in Switzerland. + +.............................. + +From: An Introduction to Pharmacology 3rd edition, JJ Lewis, 1964 (p 385) + +Peripheral Actions + +These include an oxytocic action and constriction of the blood vessels +of isolated vascular beds. In intact animals LSD causes a fall in +blood pressure, but its adrenergic blocking potency is low. + +LSD causes mydriasis in man and other species. It also causes +hyperglycaemia and mydriasis, has a hyperthermic action and causes +piloerection. These effects are sympathetic in nature and are +abolished by ganglion blocking or adrenergic blocking agents. +Parasympathetic effects include salivation, lachyrmation, vomiting, +hypotension, and brachycardia. Low doses stimulate respiration but +larger doses depress it. + +(nb: mydriasis = pupillary dilation) +.............................. + +Hoffman thought the diethylamide version of the lysergic acid molecule +might be a respiratory stimulant... + +.............................. + +The "speedy" quality of unadulterated LSD is due to the pharmacological +actions of LSD itself, and not necessarily due to decomposition or impurities. +LSD typically causes early adrenergic effects such as sweating, nervousness, +jaw grinding and insomnia which are easily confused with the side effects +of amphetamine. + +****************************** + +ADDICTION POTENTIAL: + +Zero physical addiction potential. Not something that makes you want to +do it again immediately. Rarely people use it to escape in a negative +way or as part of "polydrug abuse" behavior or pattern of behavior. + +****************************** + +ADULTERANTS: + +Several problems are associated with street drugs: their unknown +purity and their unknown strength. Because of its extreme cheapness +and potency, the purity of LSD in blotter form is not an issue: either +it's lsd or untreated paper. The purity of powders, pills, and liquids +cannot be assumed as safe. With regards to uncertain strength, the +strength of hits these days is low, 100 micrograms or so. One should +be careful and assume that the smallest square in a tiling of a sheet +is a dose, even if a printed pattern covers several. An experienced +person could judge the strength of a dose, and if it is assumed all +doses on a sheet have been processed equivalently, those doses would +be calibrated for others, much like anything else. + +.............................. + +>From _Psychedelic Chemistry_ by M.V.Smith, 2nd edition p 5: + +"There is a great deal of superstition regarding purification of +psychedelics. Actually, any impurities which may be present as a +result of synthetic procedures will almost certainly be without any +effect on the trip. If there are 200 micrograms of LSD in a tablet, +there could only be 200 mics of impurities present even if the LSD was +originally only 50% pure (assuming nothing else has been added), and +few compounds will produce a significant effect until a hundred to a +thousand times this amount has been ingested. Even mescaline, which +has a rather specific psychedelic effect, requires about a thousand +thimes this amount." + +.............................. + +Note that: 1) on a piece of paper, vs. a tablet, you can't even add +significant amounts of adulterants 2) adulterants would cost, whereas +blank paper will rip someone off just as well. + +LSD itself has some "body-kinks" on some people some times. nausea is +one of them. its usually mild and transient. it also has speedlike +(ie, adrenergic stimulation) effects, etc. + +.............................. + +[Referring to strychnine] 15 mg has been fatal, but a more typical fatal +dose is on the order of 50mg. [Another post indicates 25 mg. as the LD50] 1 +mg of strychnine orally probably has no observable pharmacological effects +in a typical adult. [1 mg being ten times the effective dose of LSD, by the +way.] + + +Actually, I think the fact that PharmChem analyzed something on the order of +2,000 LSD samples between 1972 and 1979 and never found one with strychnine +in it would be better. I'm going over all their data with a toothpick and +I'll get back to you on exactly what I find. It looks like the percent of +LSD with strychnine in it is, however, at least under .05%. More a little +later. + + +.............................. + +>From "The PharmChem Newsletter" (vol 3, no 3), 1973: + +Summary of Street Drug Results - 1973: "Of 189 samples of LSD quantitatively +analyzed, the average dose was 67.25ug LSD. Of the 32 samples of alleged +mescaline actually containing mescaline, [...stuff about mescaline and +mushrooms deleted...] It is interesting to note the low incidence of +deception among the less sought after psychotomimetics LSD and PCP." + +.............................. + +This is the PharmChem analysis of LSD from 1972 (vol 1, no 1) up to the time +that the DEA no longer allowed them to make quantitative measurements (1974- +vol 3, no 2 included). NOTE: NO STRYCHNINE! also note that PharmChem found +a sample of Shrooms contaminated with Strychnine in 1972 (vol 1, no 7), and +I would think it safe to assume that they also checked LSD for Strychnine. + + +****************************** + +BAD TRIPS: + + A person on LSD who becomes depressed, agitated, or confused may +experience these feelings in an overwhelming manner that grows on +itself. The best solution is to remove disturbing influences, get to +a safe, comforting environment, and reassure the tripper that things +are alright. It may comfort those who fear that they are losing their +minds to be reminded that it will end in several hours. + +Authorities are fond of administering injections of anti-psychotic +drugs. Recovery in the presence of authorities, in hospitals or +police stations, is not pleasant. Sedatives or tranquilizers such as +Valium may help reduce panic and anxiety, but the best solution is +calm talking. Some claim that niacin (an over the counter vitamin +supplement) can abort a trip, but this may be due to a placebo effect +(niacin produces a flushing effect). + +****************************** + +MYTHS: + +LSD does not form "crystals" that reside in the body to be "dislodged" +later, causing flashbacks. LSD is a crystalline solid (though it is +unlikely that one would ever have enough to be visible to the naked +eye) but it is easily water soluble, thus cannot form bodily +deposits. Furthermore, it is metabolized and excreted in hours. The +bogus "loosened crystal" description in not necessary to explain +flashbacks, which are psychological phenomena (see FLASHBACKS). + +LSD does not cause chromosome damage. + +In Science 30 April 1972, Volume 172 Number 3982 p. 431-440 there was an +article by Norman I. Dishotsky, William D. Loughman, Robert E. Mogar and +Wendell R. Lipscomb titled "LSD and Genetic Damage - Is LSD chromosome +damaging, carcinogenic, mutagenic, or teratogenic?". They reviewed 68 +studies and case reports published 1967-1972, concluding "From our own +work and from a review of literature, we believe that pure LSD ingested +in moderate doses does not damage chromosomes in vivo, does not cause +detectable genetic damage, and is not a teratogen or carcinogen in man." + +Well, there's the study by Sidney Cohen which was cited here +recently, Journal of Nervous and Mental Disease, 130, 1960. The +following is from Jay Stevens' Storming Heaven: "Cohen surveyed a sample +of five thousand individuals who had taken LSD twenty-five thousand +times. He found and average of 1.8 psychotic episodes per thousand +ingestions, 1.2 attempted suicides, and 0.4 completed suicides. +'Considering the enormous scope of the psychic responses it induces,' +he concluded, 'LSD is an astonishingly safe drug.'" + + +Some urban legends: I've heard two "stories" about people blinding +themselves on "drugs". One was revealed as a hoax by the person who +perpetrated it (apparently it was intended to "illustrate" the dangers +of LSD), another is trotted out by anti-drug speakers at high schools: + +1) Seven people on LSD stared at the sun and lost 90% of their reading + vision. + +2) A teenager arrested while on LSD plucked out his eyeballs in his + jail cell, and felt no pain. + +While these are bogus, the drug has powerful effects on the mind +and the consumer should be aware of the hazards, and act appropriately. + +.............................. + +There is an occasionally circulated fake warning from some police department +about LSD-laced "tattoos" or stickers (the "blue star tattoo" story) being +given to children. This probably originated with some hick cop or ignorant +and panicky parent not understanding some children-cartoon (eg, mickey mouse +in sorcerer's garb) printed on a sheet of blotter. + +.............................. + +See also myths about testing in DRUG TESTING + + +****************************** + +DANGERS: + +Purely psychological hazards, not harmful to body. May release latent +psychosis or exacerbate depression, leading to irrational behavior. There +is also a danger of foolish or incautious behavior, e.g, misjudging +distances or thinking one can fly. Physical overdose is not a hazard, +though one may easily ingest more than one may be able to handle +psychologically. + +.............................. + +Because the "LSD psychosis" is not distinguishable from non-drug- +induced psychosis, we have reasonable evidence to conclude that LSD +was not the sole cause of psychosis. Instead, it would seem that the +drug brought on the problems in vulnerable individuals. +Interestingly, the rate of parental alcoholism was found to be much +higher in LSD patients than in other patients or in the general +population by one study (Vardy and Kay, Arch-Gen-Psych, 1983 40(8): +877-83). + +.............................. + +Lethal (toxic) doses of LSD are conservatively several tens of +thousands of times as much as a normal dose, making it (in the toxic +sense) one of the safest drugs known. See section on Pharmacology for +description of bodily side-effects. + + The LD50 for psilocybin (active ingredient in mushrooms) is 275 mg/kg +i.v. in mice. Of course, it would take lots more p.o. to kill someone. + + The reported LD50 values for LSD are 46, 16.5, 0.3 mg/kg I.V. for mice, +rats, and rabbits, respectively. Again, it's hard to accurately translate +these numbers to oral values. + +Note that an average human dose is 0.001 mg/kg, ie, 1 microgram/kg, ie, +1 part per billion by weight. + +.............................. + +Never take any drugs while pregnant. + +****************************** + +FLASHBACKS: + + Quoted without permission from 'Licit and Illicit Drugs,' written by +Edward M. Brecher and the editors of Consumer Reports. ISBN: 0-316-15340-0 + + A simple explanation of LSD flashbacks, and of their changed character +after 1967, is available. According to this theory, almost everybody +suffers flashbacks with or without LSD. Any intense emotional +experience--the death of a loved one, the moment of discovery that one is in +love, the moment of an automobile smashup or of a narrow escape from a +smashup--may subsequently and unexpectedly return vividly to consciousness +weeks or months later. Since the LSD trip is often an intense emotional +experience, it is hardly surprising that it may similarly "flash back." + + + +"Post-traumatic stress disorder has been commonly associated with war +veterans, but it also affects victims of disasters and violence... Experts +estimate that 1% of the population suffers from the disorder." +---LA Times, Feb 18 1992, p A3, "Journey For Better Life Hell For Some Women." + + +****************************** + +INSOMNIA: + +Insomnia occurs frequently after the trip. A mild, over-the-counter +sleeping aid can help, and these antihistamines do not produce adverse +interactions. Also, some people like to consume a small amount of alcoholic +beverage to "smooth the jitteries". The usual precautions about sleeping +aids if alcohol has been consumed apply of course. + + +****************************** + +TOLERANCE: + +Aquired rapidly, within 3 days. Tolerance dissipates equally rapidly, +without withdrawal, craving, or symptoms of addiction. + +Cross-tolerance can and is developed between other indole hallucinogens, eg, +DMT, LSD and Psilocybin. + +****************************** + +BOTANY: + +"Indole Alkaloids In Plant Hallucinogens" Richard Evans Schultes, PhD. +Journal of Psychedelic Drugs Vol.8(No.1) Jan-Mar 1976 + +"The main constituent of the seeds of Rivea corymbosa is ergine or d-lysergic +acid amide. Minor alkaloids present are the related d-isolysergic acid amide +(isoergine), chanoclavine, elymoclavine and lysergol. The seeds of Ipomoea +violacea have a similar composition, but instead of lysergol, they have +ergometrine (ergonovine). Later, very minor amounts of two alkaloids +ergometrinine and penniclavine - were found in I. violacea by chromatography. +the total alkaloid content of the seeds of Ipomoea viloacea is approximately +five times as great as that of the seeds of Rivea corymbosa: 0.06% in the +former; 0.012% in the latter. This difference in the alkaloid content +explains why Indians employ smaller doses of seeds of the Ipomoea than of the +Rivea. + +"Ethnopharmacology and Taxonomy of Mexican Psychodysleptic Plants" + Jose Luis Diaz M.D. + Journal of Psychedelic Drugs Vol. 11(1-2) Jan-Jun 1979 + +Seeds of various Morning Glories contain + Ergolines: ergine,isoergine,ergonovine + Glucosides: turbicoryn [apparently in Rivea corymbosa only] + +called Tlitlitzen (Aztec word for "The Divine Black One") +to the Aztecs, Black is a "hot" color, +a property of psychotropics associated with light + +.............................. + +"The Botanical and Chemical Distribution of Hallucinogens" +Richard Evans Schultes, PhD. +Journal of Psychedelic Drugs Vol.9(No.3) Jul-Sep 1977 + +"I. violacea, often referred to by it's synonyms I. rubro-caerulea and +I. tricolor, is represented in horticulture by a number of "varieties," +such as: Heavenly Blue, Pearly Gates, Flying Saucers, Wedding Bells, +Summer Skies, and Blue Stars - all of which contain the hallucinogenic +ergot alkaloids." + +.............................. + +"Burger's Medicinal Chemistry" Fourth Edition, Volume III +Chapter: "Hallucinogens" Alexander Shulgin + + Composition, % of total alkaloids present + ========================================= +Compound R. corymbosa I. violacea +=============== ================ ====================== +Ergine (LA-111) 54, 48 58, 10-16, 5-10 +Isoergine 17, 35 8, 18-26, 9-17 +Ergometrine 8 +Elymoclavine 4 4 +Chanoclavine 4 4 +Lysergol 4 + +Total Alkaloids .012, .04 .06, .04-.08, .02-.04 +(% of dry weight + of seeds) + + + +****************************** + +ANTHROPOLOGY: + + +_The Road to Eleusius_ by Hoffman, Wasson, and Ruck. + +Summary: A secret religion existed for 2,000 years in Greece (until +the christians displaced it around 400 AD). The initiation was open +to anyone who spoke Greek and hadn't committed murder, once in their +life. After 6 month long preparatory rituals, members walked to +Eleusius whereupon they underwent secret rituals. The rituals +remained secret until the 1970's. + +Wasson, an ethnomycological scholar and former banker (and the first +white to trip on shrooms with the mexican indians) proposed the +following explanation of the Eleusian mysteries to Hoffman, an +ergot-alkaloid expert chemist, and Ruck, a greek scholar: + +The Secret of the ritual involved the personal visions induced by +drinking the grain decoction administered to the initiates. The +domestication of grains permitted the development of greek +civilization; it also brought ergot fungus (of St. Anthony's fire +infamy). + +The thin book contains their argument for the use of the ergot fungus +in Eleusian rites, Wasson providing some background on the use of +mushrooms and grains and their role in the culture; Hoffman on the +psychoactivity of ergot strains; and Ruck on the mythological and +cultural backround of the sect. + +Evidence includes: Hoffman dosed himself with large (ergot-derived) +doses of obstetric compounds to assay their hallucinogenic potential, +and found them to possess such activity. The Eleusian temple site still +remains, but there is no room to view theatric performances, just rows of +tripping initiates, further supporting their argument. + +An interesting read, and its neat to think that the culture that +more or less lead to the western industrial one had psychedelic rites. +(Various greek prominant figures attended the rituals, including Plato). + +.............................. + + +IPOMOEA PURPUREA: A NATURALLY OCCURRING PSYCHEDELIC + +Charles Savage, Willis W. Harman and James Fadiman + +>From "Altered States of Consciousness, A Book of Readings" + edited by Charles Tart BF311.T28 + +Of the naturally occurring plant alkaloids used in ancient and modern +religious rites and divination one of the least studied is ololiuqui. The +earliest known description of its use is by Hernandez, the King of Spain's +personal physician, who spent a number of years in Mexico studying the +medicinal plants of the Indians and "accurately illustrated ololiuqui as a +morning glory in his work which was not published until 1651" (Schultes, +1960). In his words, "When a person takes ololiuqui, in a short time he loses +clear reasoning because of the strength of the seed, and he believes he is in +communion with the devil" (Alacon, 1945). Schultes (1941) and Wasson (1961) +have reported in detail on the religious and divinatory use of two kinds of +morning-glory seeds, Rivea corymbosa and Ipomoea violacea, among the Mazatec +and Zapotec indians. The first of these is assumed to be the ololiuqui of the +ancient Aztecs. + +In 1955 Osmond described personal experiments with Rivea corymbosa seeds and +reported that the effects were similar to those of d-lysergic acid +diethylamide (LSD-25). He suggested (1957) that the word psychedelic (meaning +mind-manifesting) be used as a generic term for this class of substances to +refer to their consciousness-expanding and psychotherapeutic function as +contrasted with the hallucinogenic aspect. In 1960 Hoffman reported that he +had isolated d-lysergic acid amide (LA) and d-isolysergic acid amide from the +seed of both Rivea corymbosa and Ipomoea violacea. LA is very similar to LSD +in its psychological and physiological manifestations but is reported to have +about one twentieth the psychological effectiveness of LSD (Cerletti & +Doepfner, 1958). + +The work of these investigators led us to a preliminary study of the +psychedelic properties of species of Ipomoea which are commonly found within +the continental United States. The seeds of Ipomoea purpurea, the common +climbing morning glory, resemble the seeds of Ipomoea violacea and have been +found to have similar psychedelic properties. Recent analysis by Taber et al. +(1963) has verified that LA is present in the varieties used and is probably +the primary active agent. + +The effects of the seeds of Ipomoea purpurea (varieties Heavenly Blue and +Pearly Gates) in a total of 45 cases are summarized below. The subjects are +all normally functioning adults and the majority had previous experience with +LSD. The onset of effects is about half an hour after the seeds have been +chewed and swallowed and they last from five to eight hours. + + + Low Dose, 20-50 Seeds (11 Subjects) + +This dosage rarely produces any visual distortions, although with eyes +closed there may be beginning imagery. Restlessness, evidenced by alternating +periods of pacing about and lying down, may be present. There tends to be a +heightened awareness of objects and of nature, and enhanced rapport with +other persons. A feeling of emotional clarity and of relaxation is likely to +persist for several hours after other effects are no longer noticeable. + + Medium Dose, 100-150 Seeds (22 Subjects) + +In this range the effects resemble those reported for medium-dose (75-150 +micrograms) LSD experiences, including spatial distortions, visual and +auditory hallucinations, intense imagery with eyes closed, synaesthesia and +mood elevation. These effects, which occur mainly during the period of 1 to 4 +hours after ingestion, are typically followed by a period of alert calmness +which may last until the subject goes to sleep. + + High Dose, 200-500 Seeds (12 Subjects) + +In this range the first few hours may resemble the medium-dose effects +described above. However, there is usually a period during which the +subjective states are of a sort not describable in terms of images or +distortions, states characterized by loss of ego boundaries coupled with +feelings of euphoria and philosophical insight. These seem to parallel the +published descriptions of experiences with high doses (200-500 micrograms) of +LSD given in a supportive, therapeutic setting as reported by Sherwood et al. +(1962). + +All the subjects who had previous experience with LSD claimed the effects of +the seeds were similar to those of LSD. Transient nausea was the most +commonly reported side effect, beginning about one half hour after ingestion +and lasting a few minutes to several hours. Other reported side effects not +commonly found with LSD were a drowsiness or torpor (possibly due to a +glucoside also present in the seeds) and a coldness in the extremities +suggesting that the ergine content of the seeds may be causing some vascular +constriction. (If this is the case, there may be some danger of ergot +poisoning resulting from excessive dosages of the seeds.) The only untoward +psychic effect was a prolonged (eight hours) disassociative reaction which +was terminate with chlorpromazine [Thorazine]. The possibility of prolonged +adverse reactions to the psychological effects of the seeds is essentially +the same as with LSD, and the same precautions should be observed (Cohen & +Ditman, 1963). + +.............................. + +IPOMOEA.003 7-MAY-90 + +Additional Notes: +Ipomoea purpurea is sold as the "Heavenly Blue" variety of morning glory. +"Ipomoea tricolor" is the trade name used for that variety. It is identical +with the species of morning glory described above. + +The seeds must be chewed or ground in order to be effective. Soaking the +ground seeds in water for several hours, filtering out the grounds, +and then drinking only the water portion of the mixture can reduce +some of the stomach-upset symptoms if such occur. + +Unpleasant LSD and morning glory trips can be smoothed out or even +stopped by taking niacin (in the form of nicotinic acid, vitamin B-3 or +"niacin"). Vitamin C has been shown to reduce the incidence of paranoia and +prevent depletion of the vitamin from the adrenal glands during LSD trips. + +There have been reports that commercially available packets of morning +glory seeds from some distributors are coated with fungicides or +other chemicals to increase shelf life or discourage the practice +of eating them. Seeds from plants grown in one's own garden will +be safe as long as you do not spray them with insecticides. + +The last few notes about Niacin and Vitamin C are based on +a paperback edition of Hoffer & Osmonds "The Psychedelics" + +It's pretty clear that the latin names of this plant are somewhat +confused (which is typical). Ipomoea purpurea, Ipomoea tricolor, +Ipomoea violacea and Ipomoea rubro-caerulea are all the same plant. + +The other variety of morning glory, "Ololiuhqui" has at least two +Latin names as well: Rivea corymbosa, and Turbina corymbosa. + +.............................. + +"Recreational use of Ergoline Alkaloids from Argyreia Nervosa" +William E. Shawcross +Journal of Psychedelic Drugs Vol. 15(4) Oct-Dec 1983 + +CHEMISTRY AND EFFECT OF THE SEEDS +The Hawaiian baby woodrose entered the drug scene in 1965 with the +publication of a paper in "Science" entitled "Ergoline Alkaloids in Tropical +Wood Roses" by Hylin and Watson. The wide circulation of this journal assured +thorough dissemination of the information they presented. They wrote, "The +possible health and legal problems associated with the presence of similar +compounds in commercially cultivated plants led us to examine the ornamental +wood roses, Ipomoea tuberosa and Argyreia nervosa, both common Hawaiian crops +that have assumed commerical importance as components of [the] dried tropical +flower industry." Comparing the seeds of these two plants with those of the +morning glory varieties Pearly Gates and Heavenly Blue, they found the +following yield of alkaloids (mg of alkaloid/g of seed material): + + Heavenly Blue 0.813 + Pearly Gates 0.423 + I. tuberosa [None] + A. nervosa 3.050 + +The seed of A. nervosa is the best plant source of ergoline alkaloids +discovered; it contains approximately 3 mg of alkaloidal material per gram of +seed. Approximately one-eighth of this is lysergamide. + +Hylin and Watson found the major alkaloidal constituents in A. nervosa seeds to +be ergine (780 mcg/g of fresh seed) and isoergine and penniclavine (555 mcg). + +[Note: Argyreia nervosa has NO history of shamanic use as a hallucinogen] + +This is an excerpt from the article cited. +There's no record of Argyreia being used as an hallucinogen in +India, but it was used externally as some kind of skin medicine. +There's been speculation that Argyreia might have been a component +of "Soma", but there's no evidence for that, apparently. +Because there's not a long history of human usage of Argyreia, +it may be that there are glycosides not mentioned here that +take effect at higher doses or might cause stomach upset, tachycardia +etc. The article mentioned intestinal complaints in one or two +cases at higher experimental doses. + + + + + + +****************************** + +CHEMISTRY: + +lysergic acid diethylamide _is_ lysergic acid diethylamide (or... +N,N-diethyl-D-lysergamide or... +9,10-Didehydo-N,N-diethyl-6-methylergoline-8B-carboxamide). + +Only one stereoisomer (the d-) is psychoactive. Thus, racemic (l/d 50-50 mix) +lsd shows half the potency of the dextro form. In synthesis it is possible +to recover the l-form for the lysergic acid. + +Lysergic Acid Diethylamide is LSD rather than LAD because the German word +for acid is saeure (sp). + + LSD-25 Lysergic acid + + O CH2-CH3 O + || / || + || / || + -C--N C---OH + | \ | + | \ | + |___ CH2-CH3 |___ + / \ / \ + / \ / \ + << N---CH3 << N---CH3 + \\ / \\ / + \\____/ \\____/ + / \ / \ + / \ / \ + < > < > + // \ / // \ / + // \_____/ // \_____/ + | || || | || || + | || || | || || + | || || | || || + \\ /\ / \\ /\ / + \\ / \ / \\ / \ / + N N + H H + +Ergot is a product of the fungus Claviceps purpurea. The bio-active +ingredients of ergot are all derivatives of lysergic acid. LSD is a +semisynthetic derivative of lysergic acid. Thus LSD is an +"ergot"-like substance. + +****************************** + + +MECHANISM OF ACTION: + +(Note: the mechanism of action of LSD and other psychedelics is uncertain.) + +>From a chapter titled Hallucinogens and Other Psychotomimetics: Biological +Mechanisms by S.J.Watson + +"The current thesis of the effect of indole hallucinogens on +5-hydroxytrypamine might be stated as follows: LSD acts to preferentially +inhibit serotonergic cell firing and seems to spare postsynaptic serotnergic +receptors. This preference is shared by other simillar hallucinogens but in +a limited fashion. Nonhallucinogenic analogs of LSD show no preference. +These results suggest that there are two different steric conformation of +serotonergic receptors, one of which has higher affinity for LSD than the +other. In general, 5-ht is an inhibitory transmitter; thus, when its +activity is decreased, the next neuron in the chain is freed from inhibition +and becomes more active. Since serotnergic systems appear to be intimately +involved int eh control of sensation, sleep, attention, and mood, it may be +possible to explain the actions of LSD and other hallucinogens by their +disinhibition of these critical systems. + +There is also evidence for interaction with dopaminergic systems. + +.............................. + +LSD acts as a 5HT autoreceptor agonist in the raphe nucleus. These +autoreceptors are typically considered to be 5HT1As. It also acts as a 5HT2 +agonist, which is thought to be the main site of hallucinogenic activity. +It's probably best called a a mixed 5HT2/5HT1 receptor partial agonist. + +I don't know of its effects on dopamine. Wouldn't be surprised if it has +'em; the systems aren't really functionally separable. The DA effects +wouldn't be necessary for hallucinogenic activity, I'd bet. + +.............................. + +>"If there's no documentation, you can't tell bugs from features." ---C.P. + +****************************** + +RELATED COMPOUNDS: + + + +Related compounds are the indole hallucinogens including DMT +(dimethyl-tryptamine), DET (diethyl-), etc.; psilocybin; lysergic acid. DMT +is very fast acting, lasting less than an hour. Psilocybin, found in +hallucinogenic (aka magic or mexican) mushrooms, has effects similar to LSD +but they work for approximately half the duration. These are all indole +derivatives like the neurotransmitter serotonin, 5-hydroxy-tryptamine. +"Indole" is the name of the 6-carbon ring attached to the 5-ring containing +a nitrogen. The lysergic acid molecule contains an indole structure plus +additional rings. + +LSD's two ethyl groups hanging off the amine may be replaced with +other carbon chains for compounds with different durations, potencies, +and effects. + +While LSD is semi-synthetic, DMT and psilocybin are found in nature. +See the sections on BOTANY and ANTHROPOLOGY for info on related +natural (plant) compounds and their uses. + +.............................. + + 1) DMT, DET, psylocin, psylocybin, : The mushroom psylocybin cubensis +contains all four of these indole derivatives, as well as others. DMT is +dimethyltryptamine, an indole derivative which has functionalized at the 3 +position with the dimethyl ethylamine group. It is a close relative to the +amino acid, tryptophan, which until recently was available in bulk at +vitamin shops, until some jerk poisoned himself by taking a wonga dose of +it. [Actually it may have been a single toxic batch mistakenly produced in +Japan.] A prep came out in 1984 for LSD using l--tryptophan as the +precursor, so this may have facilitated the government's pullin it from the +shelves. I can't find tryptophan anywhere, now, and I've tried, bud. + DMT, and it's brother DET (diethyltryptamine), have no oral activity, +so have to be smoked. They stink like fish oil when lit, though. Both have +hallucinogenic effects within 2-3 minutes of toking, wand while DMT lasts +for only a half hour, DET is a smoother, more euphoric high, lasting twice +as long. DET has effects similar to psylocybin. + Psylocybin is DMT which has a functional group, phosphoryloxy-, at the +4 position on the indole ring. This group is immediately converted to +hydroxyl- as soon as the stuff hits your stomach to give the cousin, +psylocin. In preparing the drug, then, it is not necessary to proceed beyond +the psylocin. + DMT and DET are easily derived from many indole derivatives, the +easiest of which is indole-3-acetic acid. I've done this reaction and it +stinks to high heaven of indole gunge, skatoles (methylindoles), and +indenes. Bad news if you want to make it at home, because the stench is +pervasive. Other derivatives, using phenyl or butyl groups have been +reported as having oral activity, so it is not necessary to smoke the stuff. +Doses run at about a hundred mgs for smoked drug, while psylocin is orally +active at about 5 mgs. + For a good reference work on these compounds, their preps, and effects, +see Michael Valentine Smith's "Psychedelic Chemistry," publisher unknown. + + + Your Friendly Neighborhood Chemical + Dude, + St. Theo + + +.............................. + + DMT + CH + / 3 + // \\--- --- CH CH N + || || || 2 2 \ + \\ //\ / CH + N 3 + H + + + +****************************** + +MANUFACTURE: + +Forget it. Precursors (ergot alkaloids, used medicinally for migraines and +ob/gyn due to their vasoconstrictive effects) are closely watched. (They +are obtained through commercially cultured ergot fungus; one could +theoretically extract lsyergic amides from morning glory or Hawaiian wood +rose seeds.) (Though there are routes to synthesize lysergic acid from +"scratch", these are complicated also.) Other typically needed chemicals +are very dangerous. Serious experience in organic chemistry lab would be +necessary. If you have to ask where to find the recipes, you don't know +enough about chemistry to try it. (For the curious: the _Anarchists +Cookbook_ is a bad place to start. _Psychedelic Chemistry_ is better, the +patent office or chem. lit. better.) And you'll probably trip during +manufacture if you actually succeed. Its easier and safer to buy it on the +black market. + + +****************************** + +DRUG TESTING: + +No risk. Its not looked for, hard to find, and transient. + +.............................. + + +"A maximum concentration of 2-8 ng/ml [Plasma concentration of LSD] + was reached 1.0-1.25 h after an oral dose of 160 ug. + ...[A] value of 2.9 h for the elimination half-life of LSD from + plasma [was reached]. + [Upshall, D.G., Wailling, D.G.: The determination of LSD in + human plasma following oral administration. + Clinica Chimica Acta 36, 67-73 (1972)] + +Second of all, LSD and its metabolites are detectable in the urine +for much longer than one hour. + +"LSD and its metabolites were still detectable in human urine for + as long as 4 days after the ingestion of 0.2 mg of the drug. + [Faed, E.M., McLeod, W.R.: A urine screening test of lysergide. + Journal of Chromatographic Science. 11, 4-6 (1973)] + +Note that standard, cheap initial drug screening does not use +chromatography or mass-spectrometry, and does not look for LSD. + +.............................. + +Spinal taps are not particularly useful (cerebro-spinal fluid doesn't +concentrate LSD or metabolites) and are never done under any +circumstances: they are painful and dangerous. + +.............................. + + +You might want to mention that Abbie Hoffman's _Steal This Urine Test_ +has a table which claims lsd is detectable for 40 days. I'm almost sure +this was a typo. + +.............................. + + +> 1] How long can LSD be detected in the body? + +This varies by the test being used, the detection limit placed on the test, +the point of collection and type of the sample fluid, the amount of LSD that +was taken, and the individual in question. + +Assuming the testers are using an RIA screening test with the cutoff set at +0.1 ng/ml and assuming that the user has recently emptied their bladder, +then the detection limit for one hit (100 ug) is normally around 30 hours. +Each doubling of the initial amount will add about 5 hours. Thus taking 8 +hits will leave a user vulnerable for approximately 2 days. (NOTE: This is +based on the data in [7]) + +> 2] What exact form of test can be used to detect LSD in the body? There +are a number of tests which can be used to detect LSD in the body. + +Abuscreen, a product of Roche Diagnostic Systems, is a series of +RadioImmunoAssay (RIA) tests, one of which is used to detect LSD and its +metabolites in whole blood, serum (blood), urine and stomach contents [1]. +RIA can in theory be used to detect quantities as small as 0.020 nanograms +(ng) per milliliter (ml) of sample [2]. Laboratory tests have shown that +RIA results are accurate down to at least 0.1 ng/ml [3]. The manufacturer +recommends limiting the cutoff to 0.5 ng/ml. + +EMIT, a product of Syva Corporation, is another series of tests, one of +which can be used to detect LSD and its metabolites in serum and urine. +EMIT stands for Enzyme Multiplied Immunoassay Technique. + +Both EMIT and Abuscreen are "positive/negative" response tests (much like +pregnancy tests) which require periodic equipment calibration and consume +chemicals for each test performed. A basic battery of tests costs approx. +$15-$25 per person [4]. The basic tests (recommended by NIDA) include +marijuana, cocaine, amphetamines, opiates, and phencyclidine (PCP). +Normally, unless an (employer) specifically requests the test, an LSD assay +is not run. + +Both Roche and Syva recommend confirmation of positive results by using a +different test. The usual method of confirming positive results is some +form of chromatography. These include High Performance Thin Layer +Chromatography (HPTLC)[3], and different forms of Gas Chromatography/Mass +Spectrometry (GC/MS)[5][6][7][8][9]. HPTLC and GC/MS can be used to give +quantitative results as opposed to the Boolean results from EMIT or +Abuscreen. Laboratory tests have shown that GC/MS test for LSD in urine[6] +and blood[7] can be accurate down to 0.1 ng/ml. The cost for confirmation +of a positive screening test is approximately $50-60. + +Positive results to either EMIT and RIA are held to be "probable cause" by +U.S. courts. GC/MS results are held to be "proof" by U.S. courts. + +> I am asking for an actual text message containing a short, precise > +description of each test, + +Immunoassays chemicals are created by injecting animals (rabbits, sheep, +donkey, etc) with the drug to be tested for and an albumin which force the +animal to produce antibodies. The antibodies are then removed from the +animal, purified and bottled. In RIA tests, the antibodies are then added +to the fluid sample with a radioactively labeled chemical. Any of the drug +(or similar chemicals) found in a sample that is being tested will react +with this glop and by measuring the radioactivity, the amount of drugs can +be determined [2][10]. + +> 3] How can such a test be beaten? + +While there is some literature on adulterating urine samples to produce +false negative results [11], there has been little written that applies +specifically to the LSD screening tests. + +I would suggest you read the article posted by Paul Hager paying particular +attention to the warning about water intoxication [12]: +In <1991May7.141615.16477@news.cs.indiana.edu> hagerp@iuvax.cs.indiana.edu wrote ++ Recommended: "Dealing With Urine Tests on Short Notice" ++ by Dale Gieringer, California NORML ++ ++ Most folks recommend that people hydrate themselves -- the idea ++ being that by drinking water and taking a diuretic that will ++ promote water loss, the urine will be very dilute and THC metabolite ++ content from "tomatoe" consumption will drop below the 100 ng/ml ++ threshold that defines a "positive". ++ ++ Mr. Gieringer recommends that, the day before the test, the ++ person drink lots of water. I would amend this to, drink your ++ normal "8 glasses" plus a few more. Don't get carried away with ++ drinking water -- there is such a thing as "water intoxication" ++ which can result in brain swelling and other nasties so don't ++ chug-a-lug a gallon of water just before the test. After ++ hydrating, and a little before the test, drink some more water ++ and use a diuretic (coffee is a weak diuretic). Urinate to ++ flush the bladder -- the first urination of the day is the ++ one most charged with metabolites. The pamphlet quotes from ++ a _High Times_ article, "How to Beat a Drug Test": ++ ++ Take an 80 mg dose of the prescription diuretic Lasix ++ (furosemide); take a hefty drink of water; piss two ++ or three times; then take the test. ++ ++ Some caution is to be exercised in taking diuretics. Consult ++ your physician. ++ ++ Mr. Gieringer also suggests that the clear, watery urine that ++ results from the above procedure is sometimes suspicious. He ++ recommends taking 50-100 mg of vitamin B2 which will color ++ urine yellow for a couple of hours. Vitamin C does not produce ++ this effect -- contrary to rumor. ++ ++ For more information, I'd suggest contacting California NORML ++ directly at (415) 563-5858. They are located in San Francisco. ++ It is also possible that Mr. Gieringer will respond directly ++ via his canorml account. + +> I am asking for ...[a description]... of each thing that LSD leaves behind +> that can be detected, and of each method used to beat each test. + +The immunsoassay tests vary in their specificity. Some display a relatively +low cross-reactivity[13], others a high cross-reactivity[14]. The exact +metabolites of LSD in humans have not been fully determined yet, though +animal studies have been done. The only verified human metabolite I could +find in the literature was N-demethyl-LSD[6] but I did not check all the +references. + +FOOTNOTES: +[1] +Altunkaya, D; Smith R.N. +"Evaluation of a commercial radioimmunoassay kit for the detection of +lysergide (LSD) in serum, whole blood, urine, and stomach contents" +Forensic Science International. v47n2, September 1990, p113-21. +[2] +Taunton-Rigby, A.; Sher, S.E.; Kelley, P.R. +"Lysergic Acid Diethylamide: Radioimmunoassay" +Science. v181, July 13 1973, p165-6. +[3] +McCarron, M.M.; Walberg, C.B.; Baselt, R.C. +"Confirmation of LSD intoxication by analysis of serum and urine." +Journal of Analytical Toxicology. v14n3, May-June 1990, p165-7. +[4] +Berg, E. +"Drug-testing methods: what you should know." +Safety & Health. v142n6, Dec 1990, p52-6. +[5] +Lim, H.K.; Andrenyak, D.; Francom, P.; Bridges, R.R.; Foltz, R.L. +"Determination of LSD in urine by capillary column gas chromatography +and electron impact mass spectrometry." +Journal of Analytical Toxicology. v12n1, Jan-Feb 1988, p1-8. +[6] +Lim, H.K.; Andrenyak, D.; Francom, P. +"Quantification of LSD and N-demethyl-LSD in urine by gas chromatography/ +resonance electron capture ionization mass spectrometry." +Analytical Chemistry. v60, July 15 1988, p1420-25. +[7] +Papac, D.I.; Foltz, R.L. +"Measurement of lysergic acid dietylamide (LSD) in human plasma by gas +chromatography/negative ion chemical ionization mass spectrometry." +Journal of Analytical Toxicology. v14n3, May-June 1990, p189-90. +[8] +Paul, B.D.; Mitchell J.M.; Burbage, R.; Moy, M; Sroka, R. +"Gas chromatographic-electron-impact mass fragmentometric determination +of lysergic acid diethylamide in urine." +Journal of Chromatography. v529n1, July 13, 1990, p103-12. +[9] +Blum, L.M.; Carenzo, E.F.; Rieders, F. +"Determination of lysergic acid diethylamide (LSD) in urine by instrumental +high-performance thin-layer chromatography." +Journal of Analytical Toxicology. v14n5, Sep-Oct 1990, p285-7. +[10] +Ratcliffe, W.A.; Fletcher, S.M.; Moffat, A.C.; et. al. +"Radioimmunoassay of Lysergic Acid Diethylamide (LSD) in serum and urine +by using antisera of different specificities." +Clinical Chemistry. v23n2, Feb 1977, p169-74. +[11] +Cody, J.T.; Schwarzhoff, R.H. +"Impact of adulterants on RIA analysis of urine for drugs of abuse." +Journal of Analytical Toxicology. v13n5, Sep-Oct 1989, p277-84. +[12] +Klonoff, D.C. +"Acute water intoxication as a complication of urine drug testing in the +workplace." +Journal of the American Medical Association. v265n1, Jan 2 1991, p84-6. +[13] +Christie J.; White, M.W.; Wiles, J.M. +"A chromatographic method for the detection of LSD in biological liquids." +Journal of Chromatography. v120n2, May 26, 1976, p496-501. +[14] +Twitchet, P.J.; Fletcher, S.M.; Sullivan, A.T.; Moffat, A.C. +"Analysis of LSD in human body fluids by high-performance liquid chromatography, +fluorescence spectroscopy and radioimmunoassay." +J. Chromatogr. v150n1, March 11 1978, p73-84. + +Sorry this was so long but I thought it deserved it :-) +Enjoy a "referenced" article. +Tim Basher + +.............................. + +There were rumors going around that LSD could be detected +by drug tests fo thirty days. I think this reference and +abstract makes it clear that it is probably 4 days, max. +(see the end of the abstract) + + IDNUM 03319915 + TYPE Journal paper + DATE 880715 + AUTHOR Heng Keang Lim; Andrenyak, D.; Francom, P.; Foltz, R.L.; Jones, R.T. + Center for Human Toxicology, Utah Univ., Salt Lake City, UT, USA + TITLE Quantification of LSD and N-demethyl-LSD in urine by gas + chromatography/resonance electron capture ionization mass + spectrometry + SOURCE Analytical Chemistry; vol.60, no.14; 15 July 1988; pp. 1420-5 + SUBJECT chromatography; electron capture; mass spectroscopic chemical + analysis; organic compounds; quantification; gas chromatography; + resonance electron capture ionisation mass spectrometry; LSD; + N-demethyl-LSD; urine; lysergic acid diethylamide; human; in vitro; + in vivo; aromatic hydroxylation; drug; metabolite; + N-tri-fluoroacetyl derivatives; calibration curves; urinary + concentrations; adult volunteer; excretion; elimination half-lives; + 4 to 6 hrs; 8 to 10 hrs + Numerical data: time 1.4E+04 to 2.2E+04 s; time 2.9E+04 to 3.6E+04 s + Class codes: A8280M; A8280B; A3470 + CODEN ANCHAM + ABSTRACT Demethylation of lysergic acid diethylamide (LSD) in the human has + been demonstrated, both in vitro and in vivo, and aromatic + hydroxylation at positions 13 and 14 has been tentatively + identified. A gas chromatography/resonance electron capture + ionization mass spectrometry (GC/MS) assay for LSD and + N-demethyl-LSD in urine has been developed, in which the drug and + its metabolite are converted to their N-tri-fluoroacetyl derivatives + prior to GC/MS analysis. Linear and reproducible calibration curves + have been obtained for LSD concentrations from 0.05 to 5.0 ng/mL, + and for N-demethyl-LSD concentrations from 0.03 to 5.0 ng/mL. The + assay was used to determine the urinary concentrations of LSD and + N-demethyl-LSD following administration of a single oral dose of the + drug (1 mu g/kg) to an adult volunteer. The rates of excretion of + LSD and N-demethyl-LSD reached maxima in urine collected at time + intervals of 4-6 and 8-10 h after administration, respectively. The + elimination half-lives for LSD and N-demethyl-LSD were 3.6 and 10.0 + h, respectively + MISCELLANEOUS + Treatment: experimental + Anal. Chem. (USA) + Abstract number(s): A89037987 + ISSN: 0003-2700 + Refs: 15 + +****************************** + +LEGAL SCHEDULING: + +Class I, "no medical use" --- mostly for political reasons, as it was +and is used in psychotherapy. (Current use is in Switzerland.) + + +****************************** + +SET and SETTING: + +"SET" is the expectations a person brings with them. "Setting" is the +environment that a person is in. Set includes expectations about the +drug's actions and how the person will react. Setting includes the +social and physical conditions. For LSD and the hallucinogen-type +drug more than other psychoactives, set and setting are very important +in determining the nature of the experience. These factors make the +difference between, e.g., the experiences of someone taking the drug +for enhancement at a concert, for psychotherapy in an doctor's office, +in a religious context, or in the outdoors for an aesthetic +experience. For best results, one should take LSD only with people +one trusts in safe, comfortable surroundings, free of everyday +intrusions. Tripping alone is a very risky thing to do, that +inexperienced people should avoid. + +****************************** + +STORAGE: + +First, note that LSD is a fairly stable organic molecule, no more or +less fragile than other molecules with comparable structures. + +The main factors to be concerned with are moisture (due to leaching +and facilitated chemical reactions in the presense of moisture), +oxygen, light, and temperature. Reaction rates typically depend upon +temperature exponentially. These factors basically apply to all +organic compounds. + +Sealing in AL foil in a cool dark place is fine. Some recommend +refrigeration, but be careful about nosy guests, condensation, and frost. +Multiple, redundant seals are suggested, eg., paper in metal foil in +plastic in a metal candy tin which has been taped shut. Should last +at least a presidential term. + +Wallets are contraindicated as storage locations due to sweat. + +****************************** + +SYNERGIES, BAD COMBINATIONS: + +Smoking cannabis products considerably increases the effects, +increasing the visuals and also possibly increasing the cognitive and +linguistic disorders. As the effects of LSD wear off, marijuana may +bring them back, and also ease the jitteriness some dislike. Nitrous +oxide goes well with LSD, though one should be extra careful (not to +suffocate or fall down) with the nitrous because of the effects of the +LSD. MDA & cousins can go well, but people on these drugs should not +take LSD unless they are familiar with the latter's effects. + +Alcohol's effects are largely overwhelmed by LSD, and they act in opposite +ways: alcohol being a depressant and LSD being a (hyper)stimulant. +Generally mixing stimulants and sedatives is counterproductive. + +MAO inhibitors ??? +Amphetamines and cocaine ??? + +****************************** + +SYNTHESIS: + +Don't try it, too difficult and risky both physically and +legally. Precursor medical drugs (ob/gyn and migraine ergot +alkaloids) are watched. + +****************************** + + + + +REFERENCES & FURTHER READING: + + HISTORICAL: +LSD: My Problem Child [A. Hofmann, PhD] (excellent) +Storming heaven : LSD and the American dream [Jay Stevens]. (excellent) +Ceremonical Chemistry [T. Szasz, M.D.] (excellent) +Acid Dreams +Drugs and the Brain +Psychedelics Reconsidered +Electric Koolaid Acid Test +Flashbacks (Leary's autobiography) +The Great Drug War +Dealing With Drugs + + USAGE/INFORMATIONAL: +Psychedelic Encyclopedia [Stafford] (excellent) +Psychedelic Chemistry [M.V.Smith] +Biochemical Basis of Neuropharmacology (technical) +Consumer Reports: Licit & Illicit Drugs +Recreational Drugs + + REFERENCE: +Merck Handbook +Physician's Desk Reference +The Botany And Chemistry Of Hallucinogens, Shultes & Hofmann + + JOURNALS: +Journal of Psychoactive (formerly Psychedelic) Drugs + + + +.............................. + + AUTHOR: Cohen, Sidney + AUTHOR AFFILIATION: + U California School of Medicine, Neuropsychiatric + Inst, Los Angeles + TITLE: LSD: The varieties of psychotic experience. + SOURCE: Journal of Psychoactive Drugs 1985 Oct-Dec Vol 17(4) + 291-296 + ABSTRACT: Discusses the contributing factors (e.g., preexisting + character structure, insecurity, negative experience, + current mood and stress level) and prevention and + treatment of acute and prolonged psychotic reactions + to LSD. (10 ref) + +.............................. + + +Additional (detailed) References (in random order): + +"Indole Alkaloids In Plant Hallucinogens" Richard Evans Schultes, PhD. +Journal of Psychedelic Drugs Vol.8(No.1) Jan-Mar 1976 + +"Ethnopharmacology and Taxonomy of Mexican Psychodysleptic Plants" + Jose Luis Diaz M.D. + Journal of Psychedelic Drugs Vol. 11(1-2) Jan-Jun 1979 + +"The Botanical and Chemical Distribution of Hallucinogens" +Richard Evans Schultes, PhD. +Journal of Psychedelic Drugs Vol.9(No.3) Jul-Sep 1977 + +"Burger's Medicinal Chemistry" Fourth Edition, Volume III +Chapter: "Hallucinogens" Alexander Shulgin + + +J. Psychoactive Drugs Vol 21 (1) Jan-Mar 1989 + +The Addictvie Behaviors: treatment of alcoholism, drug use, smoking, and +obesity +W.R. Miller, Ed +(small amount of info on use of psychedelics in psychotherapy) +Pergammon press 1986 + + +Biological Basis Of Behavior +N.Chalmers R. Crawley S.P.R.Rose Eds +Open Univ Press Harper & Row1971 + +Recreational Drugs +Young Klein Beyer +Collier Books, div of Macmillan pub co 1977 + +The Biochemical Basis Of Neuropharmacology +J.R.Cooper F.E.Bloom R.H.Roth +Oxford Univ Press 1982 (4th ed) + +Craving For Ecstasy: Consciousness And Chemistry Of Escape +H.Milkman S.Sunderwirth +Lexington Books, DC Heath and co 1987 + +A Primer of Drug Action +R.M.Julian +W.H.Freeman & Co.1978 + + + +LSD & Creativity +O.Janiger, M.D.de Rios +J. Psychoactive Drugs Vol 21 (1) Jan-Mar 1989 + +An Introduction To Pharmacology +J.J.Lewis +Williams and wilkins Co, Baltimore 1964 (3rd edition) + +Metabolism Of Drugs Of Abuse +Spectrum Publications 1976 +Dist by Halstead Press of John Wiley Press +L. Lemberger + +Medicinal Chemistry: a series of monographs +G.deStevens Ed +Vol 4: Psychopharmaceutical agents +M. Gordon (ed) +Vol I, ch 13: psychomimetic compounds D.F.Downing +Vol II, ch 4: psychomimetic agents by A.T.Shulgin +Academic press 1976 + +The Road To Eleusis +Unveiling the secret of the mysteries +R.G.Wasson, A.Hoffman, C.A.P.Ruck +harcourt brace jovanovich inc. 1978 + +Lsd Man And Society +R.C.Debold, R.C.Leaf Eds +Wesleyan U press +Middletown Conn 1967 + +Hallucinogenic Plants (A Golden Guide) New York: Golden Press +1976 +Shultes, R.E., Smith E.W. + +The Sun And The Moon +A.Weil, MD + +The Natural Mind +A.Weil, MD 1986 +Houghton-mifflin pub co. + +Sacred Narcotic Plants Of The New World Indians +H. Schleiffer ed. +Hafner press 1973 +Div of mcmillan pub co + +Moksha: Writings On Psychedlics And The Visionary Experience +A.C.huxley +stonehill pub co., NY +M.Horowitz, C. palmer Eds 1977 + +Psychedelic Chemistry +m.v.smith +2nd edition 1973 +rip off press + +Psychotropic Methoxyamphetamines: Structure And Activity In Man +S.H.Snyder, E.Richelson, H.Weingartner, LA.Faillace + +Ethnopharmacological Search For Psychoactive Drugs +Proc of a symposium in SF, Ca Jan 28-30 1967 +D.H.Efron, B.Holmstedt, N.S.Kline eds +US Dept of HEW + +The Botany And Chemistry Of Hallucinogens +R.E.Schultes, A.Hoffman +charles C Thomas Publisher +Springfield Ill 1980 + + +The Behavioral Effects Of Drugs +(Ch 4 Hallucinogens: Complications of LSD: A Review of the Literature; +Dimensions of the LSD, Methlphenidate, and Chlordiazepoxide +Experiences; LSD: Injection Early in Pregnancy Produces Abnormality +in Offspring of Rats; LSD: No Teratogenicity in Rats; Congenital +Malformation Induced by Mescaline, LSD, and Bromolysergic Acid in +the Hamster; Drug Motivated-Behavior: The Effect of Morning Glory Seeds +On Motor Activity In Chicks) (Also Includes Weil'S Study Of "Clinical and +Psychological Effects Of Marijuana In Man") +D.W. Matheson M.A. Davidson Holt Rinehart +Winston Inc 1972 + + +any textbook titled "Physiological Psychology" + +.............................. + +(about visual disturbances: ) +Migraine: the evolution of a common disorder +O. Sacks +U CAl press 1970 + +Brain Damage, Behavior, And The Mind +M. Williams +John Wiley & Sons 1979 +ch 5 Disorders of visual perception + +Mescal And Mechanisms Of Hallucinations +Heinrich Kluver +U. Chicago Press 1930 + +Drugs And The Brain +Perry Black MD, Ed +Johns Hopkins Press 1969 +behavioral effects of LSD in subhuman primates + + +Hallucinations +Sci Am +R.K.Siegal +(see also article on phosphenes in amateur scientist column in another issue) + + +Luria's _The Shattered Mind_ + + + +******************************END OF FAQ****************************** +[FYI only, consult your shamans & attorneys etc., you are self-responsible.] + + + diff --git a/textfiles.com/drugs/lsdintro.drg b/textfiles.com/drugs/lsdintro.drg new file mode 100644 index 00000000..2c1d45a2 --- /dev/null +++ b/textfiles.com/drugs/lsdintro.drg @@ -0,0 +1,91 @@ +LSD +--- + I think, of all the drugs on the black market today, LSD is the most +interesting and the strangest. It is the most recent major drug to come to +life in the psychedelic subculture. Huxley experimented with mescaline many +years before psychedelics reached their mass-market proportions, but this +experimentation was not with the same frame of mind as these drugs are +handled today. Probably the great-granddaddy to the whole psychedelic +community was Antonin Artaud, who personally experimented with peyote in +Mexico. The difference between Huxley's and Artaud's experimentation was that +Huxley managed to keep his experiences under laboratory controls, which he set +up himself, whereas Artaud allowed his experiences to become part of his life. +Artaud was changed by his encounters with peyote, but is this bad? A dirty +shirt is also changed when it is washed. Through this change, Artaud was able +to see and understand ideas and concepts on a different level. He was able to +tear apart rationalizations, without regard for contemporary methods of +organization, or even contemporary versions of truth. Artaud found, in his +own way, his own truth and his own structure of values. They locked him up.... + I died at Rodez under electroshock. + I died. Legally and medically dead. + Electroshock coma lasts fifteen minutes. A half an hour or more and +then the patient breathes. + Now one hour after the shock, I still had not awakened and had +stopped breathing. Surprised at my abnormal rigidity, an attendant had gone +to get the physician in charge, who, after examining me with a stethoscope, +found no more signs of life in me. + + This passage is taken from The Artaud Anthology, published by City +Lights Publishers. I find it extremely difficult to throw this off as the +ravings of a madman for, if that be true, then there can be no truth, only +madness and sanity, logic and illogic. If one then accepts the acceptable, he +finds a narrow channel is clear, but the presence of illogic and the so-called +insanities will always pry and harp in the distance. + LSD has never caused insanity. It does not have that power. Only man +can distinguish between sanity and insanity. I have never seen an insane +bird. Granted there are some individuals who shouldn't take psychedelics, but +this is, and must be, their choice. All LSD does is allow a man to look upon +ordinary things, everyday things, and even on himself, many times for the +first time, with clarity of vision. He can look and not be hampered by false- +propped values and socially limited scope. He can look upon the world and see +beauty where it did not exist before. He can perceive the ugliness for the +first time. He can roar with laughter at the multitude of absurdities +surrounding him. He can look into himself and see truthfully the mildew and +the rot. + LSD cannot bring out latent qualities in your personality. It cannot +make you into a crazy, just as it cannot make you into a warmer, more +beautiful person. What LSD can do is show you what you as a person are +comprised of, and break down truthfully your make-up. LSD is not a religion, +and I've never found anything really divine about it at all. The real +religion, if you want to put it in those terms, is the being itself. LSD is +nothing more than a medium to discover the essence of being. + LSD, or acid, has been illegal for and last decade or so; therefore +it is readily available on the black market. When buying anything on the +black market, there are a couple of things to note, but these are especially +important with acid. + +[1> Never buy from a stranger, or on the street. +[2> Never front money. +[3> If you are holding a large amount of money, do not go anywhere alone with + someone you do not trust. Many people who have got into dealing pot and + acid are, in reality, junkies. +[4> When going to make a deal for dope, do not take a weapon with you. This is + provoking violence and legal hassles. If you don't trust the guy, then + don't deal with him. +[5> Never buy a large quantity of any drug without first sampling it. +[6> When making a deal for acid and you are at the dealer's apartment, do not + accept food or drink from him; for the real acid may be in the food rather + than the cap you sample. +[7> Bad acid is nothing more than speed, or rat poison. +[8> A long time ago there was a substance called L.B.J. going around. If you + happen to come across it, do not buy it. L.B.J. is a mixture of acid, + belladonna, and heroin. It is the freakiest, worst, most fucked-up trip + you will ever go on. Belladonna in quantity is a deadly poison. +[9> About 99 percent of all of what is claimed to be T.H.C. (synthetic pot) + that is for sale on the street is not really T.H.C. at all. The expense of + making synthetic pot is said to be about $15 per capsule, and a capsule of + alleged T.H.C. usually sells on the street for about $3 - $6. Obviously + the vendors are either philanthropists (not likely) or they are selling + you something other than T.H.C. +[10> When buying grass, watch out for damp grass or grass sprayed with sugar, + as this adds a lot of weight to the dope. +[11> Another favorite con game is "in the front, out the back". This usually + occurs when your dealer tells you he is going up to an apartment to get + your stuff, but you have to front the money, and wait for him on the + street. You may be waiting a long time. +[12> Do not attempt to smuggle any drugs across the border from Mexico. The + federal government has imposed a crackdown and they're busting people + left and right. + + ************************************************ + diff --git a/textfiles.com/drugs/lsdnfo.txt b/textfiles.com/drugs/lsdnfo.txt new file mode 100644 index 00000000..3a17328c --- /dev/null +++ b/textfiles.com/drugs/lsdnfo.txt @@ -0,0 +1,1579 @@ +MAKING LSD +------ --- + + + Common LSD, being of the strangest drugs, available to people on the +black market, is not too hard to make in your average run-of-the-mill +kitchen. LSD (Lysergic acid Diethylamide) is a complex organic mixure that +gives some people (most) a trip to the moon or other nearby celestial +body. + + +ITEMS NEEDED: +----- ------ + +1-About 200-250 grams of MORNING GLORY SEEDS or BAY HAWAIIAN WOOD ROSE +SEEDS. The Morning Glory seeds can be obtained at most plant nurseries. + +2-200 cc. of petroleum ether + +3-Small piece of window screen or a strainer + +4-A couple of large glasses + +5-cookie tray (an old one, never to be used again) + +6-260 cc. of wood alcohol (call your local drug store). + +7-Capsule containers (jel) + +========================================================================= + +Let's get started: + +1. Grind up about 170 grams of Morning Glory Seeds. + +2. In 145 cc. of petroleum ether, soak the seeds for two or three days. + +3. With screen, filter the liquid thru it and save the seed mush and +allow it to dry completely. + +4. Let the mush soak in 130 cc. of wood alcohol. + +5. Filter solution again only. Save the liquid in a large glass jar. + +6. Soak the seed mush again in 130 cc. of wood alcohol for two more days. + +7. Filter out the mush and keep the liquid. Now, get the liquid that was +saved in step 5. + +8. Now, pour both liquids in a cookie tray and let it dry. + +9. When all the liquid has dried, a yellowish gummy looking substance will +appear on the cookie sheet. + +10. Take the yellow gum and put this into capsules. + +========================================================================= + +You can get the capsules just by buying something like DEXITRIM or some +other pill. Even CONTACT comes in jel capsules. Just empty them out and +put the yellow gum in the capsules. Allow the capsules to sit over night +for best results. + + +34 Grams of morning glory=1 trip to da moon +18 Grams of hawaiian wood=Another trip to da moon + +**************************************** +* THUNDER GOD * +* GLADLY PRESENTS * +* * +* LSD * +* TAKEN FROM * +* THE ANARCHIST COOKBOOK * +* BY * +* WILLIAM POWELL * +**************************************** + +WELCOME TO MY FILE ON LSD. IN THIS I +WILL DIRECTLY WRITE THE SECTION ON +LSD FROM THE BOOK ANARCHISTS COOKBOOK + +---------------------------------------- +LSD + I THINK, OF ALL THE DRUGS ON THE BLACK +MARKET TODAY, LSD IS THE MOST INTER- +ESTING AND THE STRANGEST. IT IS THE MOST +RECENT MAJOR DRUG TO COME TO LIFE IN THE +PSYCHEDELIC SUBCULTURE. HUXLEY EXPERIMEN +TED WITH MESCALINE MANY YEARS BEFORE +PSYCHEDELICS REACHED THEIR MASS-MARKET +PROPORTIONS,BUT THIS EXPERIMENTATION +WAS NOT WITH THE SAME FRAME OF MIND AS +THESE DRUGS ARE HANDLED TODAY. PROBABLY +THE GREAT-GRANDDADDY TO THE WHOLE +PSYCHEDELIC COMMUNITY WAS ANTONIN ARTAUD +, WHO PERSONALLY EXPERIMANTED WITH +PEYOTE IN MEXICO. THE DIFFERENCE BETWEEN +HUXLEY'S AND ARTAUD'S EXPERIMENTATION +WAS THAT HUXLEY MANAGED TO KEEP HIS +EXPERIENCES UNDER LABATORY CONTROL, +WHICH HE SET UP HIMSELF,WHEREAS ARTAUD +ALLOWED HIS EXPERIENCES TO BECOME PART +OF HIS LIFE. ARTAUD WAS CHANGED BY HIS +ENCOUNTERS WITH PEYOTE, WAS THIS BAD? +A DIRTY SHIRT IS ALSO CHANGED WHEN +IT IS WASHED. THROUGH THIS CHANGE ARTAUD +WAS ABLE TO SEE AND UNDERSTAND IDEAS +AND CONCEPTS ON A DIFFERENT LEVEL. +HE WAS ABLE TO TEAR APART +RATIONALIZATIONS, WITH OUT REGAURD FOR +CONTEMPORARY METHODS OF ORGANIZATION, +OR EVEN CONTEMPORARY VERSIONS OF TRUTH. +ARTAUD FOUND,IN HIS OWN WAY,HIS OWN +TRUTHS AND HIS OWN STRUCTURES OF VALUE. +THEY LOCKED HIM UP... + + I DIED AT RODEZ UNDER ELECTROSHOCK. + + I DIED. LEGALLY AND MEDICALLY DIED. + +ELECTROSHOCK COMA LASTS 15 MINUTES. +A HALF AND HOUR OR MORE THEN THE +PATIENT BRETHES. + +NOW ONE HOUR AFTER THE SHOCK,I STILL HAD +HAD NOT AWADEND AND HAD STOPED BREATHI +. SURPRISED AT MY ABNORMAL RIDGIDRY, AN +ATTENDENT HAD GONE TO GET HE PHYSISION +IN CHARGE,WHO,AFTER EXAMINING ME,FOUND +NO MORE SIGNS OF LIFE IN ME. + +THIS PASSAGE WAS TAKEN FROM THE ARTAUD +ANTHOLOGY. I FIND THIS IMPOSSIBLE +TO THROW THIS OF AS THE RAVINGS +OF A MADMAN FOR,IF THAT BE TRUE, +THAN THERE CAN BE NO TRUTH, ONLY MADNES +AND SANITY, LOGIC AND ILLOGIC. + + +LSD HAS NEVER CAUSED INSANITY. IT DOES +NOT HAVE THAT POWER. ALL LSD DOES IS +ALLOW A MAN TO LOOK UPON ORDINARY THINGS +AND EVEN ON HIMSELF MANY TIMES FOR THE +FIRST TIME. LSD CANNOT BRINGOUT LATENT +QUALITIES IN YOUR PERSONALITY. IT CANNOT +MAKE YOU CRAZY,JUST AS IT CANNOT MAKE +YOU INTO A WARMER MORE BEUTIFULL PERSON. +WHAT LSD CAN DO IS SHOW YOU WHAT YOU AS +A PERSON IS COMPRISED OF. LSD IS NOTHING +BUT A MEDIUM TO DISCOVER THE ESSANCE OF +BEING. + + LSD HAS BEEN ILLEGAL FOR YEARS NOW, +MAKING IT AVAILABLE ON THE BLACK MARKET. +WHEN BUYING ANYTHING ON THE BLACK MARKET +FOLLOW THESE IMORTANT RULES +(TG: THESE ARE JUST COMMON SENSE BUT +SOME PEOPLE DONT USE IT) + + 1. NEVER BUY OF THE STREET OF FROM A + STRANGER. + + 2. NEVER FRONT MONEY. + + 3. IF YOU ARE HOLDING A LARGE SUM OF + MONEY NEVER GO ALONE ANYWHERE + WITH SOMEONE YOU DONT TRUST, MANY + DEALERS ARE IN REALITY JUKIES TOO. + + 4. NEVER TAKE A WEAPON WITH YOU WHEN + DEALING WITH DOPE. + + 5. NEVER BUY A LARGE QUANTITY WITHOUT + SAMPLING IT FIRST + + 6. IF YOUR ARE IN THE DEALERS APARTMENT + NEVER EXCEPT FOOD FROM HIM. + + 7. BAD ACID IS USUALLY NOTHING MORE + THAN SPEED, OR RAT POISON. + + 8. NEVER BUY L.B.J. IT IS A MIX OF + ACID,BELLODONNA,HEROIN. + +---------------------------------------- +SINCE MOST OF US CANT GET ACCESS TO A +LAB I WILL GO RIGHT TO THE SECTION ON +MAKIND LSD IN YOU KITCHIN, +---------------------------------------- +MAKING LSD IN YOU KITCHIN + 1. GRIND UP 150 GRAMS OF MORNING GLORY + SEEDS OR BABY HAWAIIAN WOOD ROSE + SEEDS. + + 2. IN 130 CC. OF PETROLEUM ETHER, SOAK + SEEDS FOR 2 DAYS. + + 3. FILTER SOLUTION THROUGH TIGHT SCREEN + THEN THROW AWAY THE LIQUID AND + ALLOW THE SEED MUSH TO DRY. + + 4. FOR ANOTHER 2 DAYS ALLOW THE MUSH TO + SOAK IN 110 CC. OF WOOD ALCHOL. + + 5. FILTER THE SOLUTION AGAIN AND SAVING + THE LIQUID IN A VIAL LABLED "1". + + 6. REPEAT STEPS 4 AND 5 PUTTIN THE + LIQUID IN VIAL "2" AND THROWIN + ` AWAY THE MUSH. + + 7. POUR THE 2 LIQUIDS IN A COOKIE TRAY + AND ALLOW TO EVAPORATE. WHEN THIS + IS DONE SCRAPE OF YELLOW MUCK,THIS + IS YOUR FINAL PRODUCT. + + +MANY COMPANIES POISON THEIR SEEDS SO +EITHER USE SEEDS U PICKED YOURSELF OR +ORDER FROM THIS COMPANY. + + CHONG'S NURSERY AND FLOWERS + P.O. BOX 2154 + HONOLULU, HAWAII + +DOSAGES + +THE POTENCY OF THIS DRUG IS MESURED +IN MICROGRAMS OR MICS. USUALLY BETWEEN +300 AND 500 MICS IS ENOUGH FOR A GOOD +TRIP. + + -------------------------------------- +HAVE FUN WITH WHAT I JUST WROTE BUT +DONT GET CAUGHT BY THE PHEDS,PENALTY IS +HIGH. BE LOOKING FOR MORE FILES BY +ME. SO TILL NEXT TIME, + KILL PHEDS,AND THOSE WHO INSIST ON +CALLING US COMPUTERBUDDIES. EVEN AFTER +U'VE THROWN THEM ACROS THE ROOM. + THUNDER + GOD + //////////// + CCRRAACCKKLE + BBUUBBRROOMM + +How to make LSD : by Dr. D-Code & The Pimp +brough to CAL by CC. +--------------------------------------- + 1. Grind up 150 grams of baby Hawaiian + wood rose seeds + 2. In 130cc of petroleum ether, soak + seeds for 2 days + 3. Filter solution thru a tight screen + 4. Throw away liquid and allow the + seed mush to dry + 5. For 2 days allow the mush to soak + in 110cc of wood alcohol + 6. Filter the solution again saving + the liquid and labelling it #1 + 7. Re-soak the mush in 110cc of wood + alcohol for 2 days + 8. Filter and throw away the mush + 9. Add the liquid from the second soak + to the solution labeled #1 +10. Pour the liquid into a cookie tray + and let it evaporate +11. When the liquid has evaporated, a + yellow gum remains +12. Scrape the yellow stuff into + capsules. +Order the seeds from a wholesaler +>onlyFrom _Psychedelic Chemistry_ by M.V.Smith, 2nd edition p 5: + +"There is a great deal of superstition regarding purification of +psychedelics. Actually, any impurities which may be present as a +result of synthetic procedures will almost certainly be without any +effect on the trip. If there are 200 micrograms of LSD in a tablet, +there could only be 200 mics of impurities present even if the LSD was +originally only 50% pure (assuming nothing else has been added), and +few compounds will produce a significant effect until a hundred to a +thousand times this amount has been ingested. Even mescaline, which +has a rather specific psychedelic effect, requires about a thousand +thimes this amount." + +.............................. + +Note that: 1) on a piece of paper, vs. a tablet, you can't even add +significant amounts of adulterants 2) adulterants would cost, whereas +blank paper will rip someone off just as well. + +LSD itself has some "body-kinks" on some people some times. nausea is +one of them. its usually mild and transient. it also has speedlike +(ie, adrenergic stimulation) effects, etc. + +.............................. + +[Referring to strychnine] 15 mg has been fatal, but a more typical fatal +dose is on the order of 50mg. [Another post indicates 25 mg. as the LD50] 1 +mg of strychnine orally probably has no observable pharmacological effects +in a typical adult. [1 mg being ten times the effective dose of LSD, by the +way.] + + +Actually, I think the fact that PharmChem analyzed something on the order of +2,000 LSD samples between 1972 and 1979 and never found one with strychnine +in it would be better. I'm going over all their data with a toothpick and +I'll get back to you on exactly what I find. It looks like the percent of +LSD with strychnine in it is, however, at least under .05%. More a little +later. + + +.............................. + +>From "The PharmChem Newsletter" (vol 3, no 3), 1973: + +Summary of Street Drug Results - 1973: "Of 189 samples of LSD quantitatively +analyzed, the average dose was 67.25ug LSD. Of the 32 samples of alleged +mescaline actually containing mescaline, [...stuff about mescaline and +mushrooms deleted...] It is interesting to note the low incidence of +deception among the less sought after psychotomimetics LSD and PCP." + +.............................. + +This is the PharmChem analysis of LSD from 1972 (vol 1, no 1) up to the time +that the DEA no longer allowed them to make quantitative measurements (1974- +vol 3, no 2 included). NOTE: NO STRYCHNINE! also note that PharmChem found +a sample of Shrooms contaminated with Strychnine in 1972 (vol 1, no 7), and +I would think it safe to assume that they also checked LSD for Strychnine. + + +****************************** + +BAD TRIPS: + + A person on LSD who becomes depressed, agitated, or confused may +experience these feelings in an overwhelming manner that grows on +itself. The best solution is to remove disturbing influences, get to +a safe, comforting environment, and reassure the tripper that things +are alright. It may comfort those who fear that they are losing their +minds to be reminded that it will end in several hours. + +Authorities are fond of administering injections of anti-psychotic +drugs. Recovery in the presence of authorities, in hospitals or +police stations, is not pleasant. Sedatives or tranquilizers such as +Valium may help reduce panic and anxiety, but the best solution is +calm talking. Some claim that niacin (an over the counter vitamin +supplement) can abort a trip, but this may be due to a placebo effect +(niacin produces a flushing effect). + +****************************** + +MYTHS: + +LSD does not form "crystals" that reside in the body to be "dislodged" +later, causing flashbacks. LSD is a crystalline solid (though it is +unlikely that one would ever have enough to be visible to the naked +eye) but it is easily water soluble, thus cannot form bodily +deposits. Furthermore, it is metabolized and excreted in hours. The +bogus "loosened crystal" description in not necessary to explain +flashbacks, which are psychological phenomena (see FLASHBACKS). + +LSD does not cause chromosome damage. + +In Science 30 April 1972, Volume 172 Number 3982 p. 431-440 there was an +article by Norman I. Dishotsky, William D. Loughman, Robert E. Mogar and +Wendell R. Lipscomb titled "LSD and Genetic Damage - Is LSD chromosome +damaging, carcinogenic, mutagenic, or teratogenic?". They reviewed 68 +studies and case reports published 1967-1972, concluding "From our own +work and from a review of literature, we believe that pure LSD ingested +in moderate doses does not damage chromosomes in vivo, does not cause +detectable genetic damage, and is not a teratogen or carcinogen in man." + +Well, there's the study by Sidney Cohen which was cited here +recently, Journal of Nervous and Mental Disease, 130, 1960. The +following is from Jay Stevens' Storming Heaven: "Cohen surveyed a sample +of five thousand individuals who had taken LSD twenty-five thousand +times. He found and average of 1.8 psychotic episodes per thousand +ingestions, 1.2 attempted suicides, and 0.4 completed suicides. +'Considering the enormous scope of the psychic responses it induces,' +he concluded, 'LSD is an astonishingly safe drug.'" + + +Some urban legends: I've heard two "stories" about people blinding +themselves on "drugs". One was revealed as a hoax by the person who +perpetrated it (apparently it was intended to "illustrate" the dangers +of LSD), another is trotted out by anti-drug speakers at high schools: + +1) Seven people on LSD stared at the sun and lost 90% of their reading + vision. + +2) A teenager arrested while on LSD plucked out his eyeballs in his + jail cell, and felt no pain. + +While these are bogus, the drug has powerful effects on the mind +and the consumer should be aware of the hazards, and act appropriately. + +.............................. + +There is an occasionally circulated fake warning from some police department +about LSD-laced "tattoos" or stickers (the "blue star tattoo" story) being +given to children. This probably originated with some hick cop or ignorant +and panicky parent not understanding some children-cartoon (eg, mickey mouse +in sorcerer's garb) printed on a sheet of blotter. + +.............................. + +See also myths about testing in DRUG TESTING + + +****************************** + +DANGERS: + +Purely psychological hazards, not harmful to body. May release latent +psychosis or exacerbate depression, leading to irrational behavior. There +is also a danger of foolish or incautious behavior, e.g, misjudging +distances or thinking one can fly. Physical overdose is not a hazard, +though one may easily ingest more than one may be able to handle +psychologically. + +.............................. + +Because the "LSD psychosis" is not distinguishable from non-drug- +induced psychosis, we have reasonable evidence to conclude that LSD +was not the sole cause of psychosis. Instead, it would seem that the +drug brought on the problems in vulnerable individuals. +Interestingly, the rate of parental alcoholism was found to be much +higher in LSD patients than in other patients or in the general +population by one study (Vardy and Kay, Arch-Gen-Psych, 1983 40(8): +877-83). + +.............................. + +Lethal (toxic) doses of LSD are conservatively several tens of +thousands of times as much as a normal dose, making it (in the toxic +sense) one of the safest drugs known. See section on Pharmacology for +description of bodily side-effects. + + The LD50 for psilocybin (active ingredient in mushrooms) is 275 mg/kg +i.v. in mice. Of course, it would take lots more p.o. to kill someone. + + The reported LD50 values for LSD are 46, 16.5, 0.3 mg/kg I.V. for mice, +rats, and rabbits, respectively. Again, it's hard to accurately translate +these numbers to oral values. + +Note that an average human dose is 0.001 mg/kg, ie, 1 microgram/kg, ie, +1 part per billion by weight. + +.............................. + +Never take any drugs while pregnant. + +****************************** + +FLASHBACKS: + + Quoted without permission from 'Licit and Illicit Drugs,' written by +Edward M. Brecher and the editors of Consumer Reports. ISBN: 0-316-15340-0 + + A simple explanation of LSD flashbacks, and of their changed character +after 1967, is available. According to this theory, almost everybody +suffers flashbacks with or without LSD. Any intense emotional +experience--the death of a loved one, the moment of discovery that one is in +love, the moment of an automobile smashup or of a narrow escape from a +smashup--may subsequently and unexpectedly return vividly to consciousness +weeks or months later. Since the LSD trip is often an intense emotional +experience, it is hardly surprising that it may similarly "flash back." + + + +"Post-traumatic stress disorder has been commonly associated with war +veterans, but it also affects victims of disasters and violence... Experts +estimate that 1% of the population suffers from the disorder." +---LA Times, Feb 18 1992, p A3, "Journey For Better Life Hell For Some Women." + + +****************************** + +INSOMNIA: + +Insomnia occurs frequently after the trip. A mild, over-the-counter +sleeping aid can help, and these antihistamines do not produce adverse +interactions. Also, some people like to consume a small amount of alcoholic +beverage to "smooth the jitteries". The usual precautions about sleeping +aids if alcohol has been consumed apply of course. + + +****************************** + +TOLERANCE: + +Aquired rapidly, within 3 days. Tolerance dissipates equally rapidly, +without withdrawal, craving, or symptoms of addiction. + +Cross-tolerance can and is developed between other indole hallucinogens, eg, +DMT, LSD and Psilocybin. + +****************************** + +BOTANY: + +"Indole Alkaloids In Plant Hallucinogens" Richard Evans Schultes, PhD. +Journal of Psychedelic Drugs Vol.8(No.1) Jan-Mar 1976 + +"The main constituent of the seeds of Rivea corymbosa is ergine or d-lysergic +acid amide. Minor alkaloids present are the related d-isolysergic acid amide +(isoergine), chanoclavine, elymoclavine and lysergol. The seeds of Ipomoea +violacea have a similar composition, but instead of lysergol, they have +ergometrine (ergonovine). Later, very minor amounts of two alkaloids +ergometrinine and penniclavine - were found in I. violacea by chromatography. +the total alkaloid content of the seeds of Ipomoea viloacea is approximately +five times as great as that of the seeds of Rivea corymbosa: 0.06% in the +former; 0.012% in the latter. This difference in the alkaloid content +explains why Indians employ smaller doses of seeds of the Ipomoea than of the +Rivea. + +"Ethnopharmacology and Taxonomy of Mexican Psychodysleptic Plants" + Jose Luis Diaz M.D. + Journal of Psychedelic Drugs Vol. 11(1-2) Jan-Jun 1979 + +Seeds of various Morning Glories contain + Ergolines: ergine,isoergine,ergonovine + Glucosides: turbicoryn [apparently in Rivea corymbosa only] + +called Tlitlitzen (Aztec word for "The Divine Black One") +to the Aztecs, Black is a "hot" color, +a property of psychotropics associated with light + +.............................. + +"The Botanical and Chemical Distribution of Hallucinogens" +Richard Evans Schultes, PhD. +Journal of Psychedelic Drugs Vol.9(No.3) Jul-Sep 1977 + +"I. violacea, often referred to by it's synonyms I. rubro-caerulea and +I. tricolor, is represented in horticulture by a number of "varieties," +such as: Heavenly Blue, Pearly Gates, Flying Saucers, Wedding Bells, +Summer Skies, and Blue Stars - all of which contain the hallucinogenic +ergot alkaloids." + +.............................. + +"Burger's Medicinal Chemistry" Fourth Edition, Volume III +Chapter: "Hallucinogens" Alexander Shulgin + + Composition, % of total alkaloids present + ========================================= +Compound R. corymbosa I. violacea +=============== ================ ====================== +Ergine (LA-111) 54, 48 58, 10-16, 5-10 +Isoergine 17, 35 8, 18-26, 9-17 +Ergometrine 8 +Elymoclavine 4 4 +Chanoclavine 4 4 +Lysergol 4 + +Total Alkaloids .012, .04 .06, .04-.08, .02-.04 +(% of dry weight + of seeds) + + + +****************************** + +ANTHROPOLOGY: + + +_The Road to Eleusius_ by Hoffman, Wasson, and Ruck. + +Summary: A secret religion existed for 2,000 years in Greece (until +the christians displaced it around 400 AD). The initiation was open +to anyone who spoke Greek and hadn't committed murder, once in their +life. After 6 month long preparatory rituals, members walked to +Eleusius whereupon they underwent secret rituals. The rituals +remained secret until the 1970's. + +Wasson, an ethnomycological scholar and former banker (and the first +white to trip on shrooms with the mexican indians) proposed the +following explanation of the Eleusian mysteries to Hoffman, an +ergot-alkaloid expert chemist, and Ruck, a greek scholar: + +The Secret of the ritual involved the personal visions induced by +drinking the grain decoction administered to the initiates. The +domestication of grains permitted the development of greek +civilization; it also brought ergot fungus (of St. Anthony's fire +infamy). + +The thin book contains their argument for the use of the ergot fungus +in Eleusian rites, Wasson providing some background on the use of +mushrooms and grains and their role in the culture; Hoffman on the +psychoactivity of ergot strains; and Ruck on the mythological and +cultural backround of the sect. + +Evidence includes: Hoffman dosed himself with large (ergot-derived) +doses of obstetric compounds to assay their hallucinogenic potential, +and found them to possess such activity. The Eleusian temple site still +remains, but there is no room to view theatric performances, just rows of +tripping initiates, further supporting their argument. + +An interesting read, and its neat to think that the culture that +more or less lead to the western industrial one had psychedelic rites. +(Various greek prominant figures attended the rituals, including Plato). + +.............................. + + +IPOMOEA PURPUREA: A NATURALLY OCCURRING PSYCHEDELIC + +Charles Savage, Willis W. Harman and James Fadiman + +>From "Altered States of Consciousness, A Book of Readings" + edited by Charles Tart BF311.T28 + +Of the naturally occurring plant alkaloids used in ancient and modern +religious rites and divination one of the least studied is ololiuqui. The +earliest known description of its use is by Hernandez, the King of Spain's +personal physician, who spent a number of years in Mexico studying the +medicinal plants of the Indians and "accurately illustrated ololiuqui as a +morning glory in his work which was not published until 1651" (Schultes, +1960). In his words, "When a person takes ololiuqui, in a short time he loses +clear reasoning because of the strength of the seed, and he believes he is in +communion with the devil" (Alacon, 1945). Schultes (1941) and Wasson (1961) +have reported in detail on the religious and divinatory use of two kinds of +morning-glory seeds, Rivea corymbosa and Ipomoea violacea, among the Mazatec +and Zapotec indians. The first of these is assumed to be the ololiuqui of the +ancient Aztecs. + +In 1955 Osmond described personal experiments with Rivea corymbosa seeds and +reported that the effects were similar to those of d-lysergic acid +diethylamide (LSD-25). He suggested (1957) that the word psychedelic (meaning +mind-manifesting) be used as a generic term for this class of substances to +refer to their consciousness-expanding and psychotherapeutic function as +contrasted with the hallucinogenic aspect. In 1960 Hoffman reported that he +had isolated d-lysergic acid amide (LA) and d-isolysergic acid amide from the +seed of both Rivea corymbosa and Ipomoea violacea. LA is very similar to LSD +in its psychological and physiological manifestations but is reported to have +about one twentieth the psychological effectiveness of LSD (Cerletti & +Doepfner, 1958). + +The work of these investigators led us to a preliminary study of the +psychedelic properties of species of Ipomoea which are commonly found within +the continental United States. The seeds of Ipomoea purpurea, the common +climbing morning glory, resemble the seeds of Ipomoea violacea and have been +found to have similar psychedelic properties. Recent analysis by Taber et al. +(1963) has verified that LA is present in the varieties used and is probably +the primary active agent. + +The effects of the seeds of Ipomoea purpurea (varieties Heavenly Blue and +Pearly Gates) in a total of 45 cases are summarized below. The subjects are +all normally functioning adults and the majority had previous experience with +LSD. The onset of effects is about half an hour after the seeds have been +chewed and swallowed and they last from five to eight hours. + + + Low Dose, 20-50 Seeds (11 Subjects) + +This dosage rarely produces any visual distortions, although with eyes +closed there may be beginning imagery. Restlessness, evidenced by alternating +periods of pacing about and lying down, may be present. There tends to be a +heightened awareness of objects and of nature, and enhanced rapport with +other persons. A feeling of emotional clarity and of relaxation is likely to +persist for several hours after other effects are no longer noticeable. + + Medium Dose, 100-150 Seeds (22 Subjects) + +In this range the effects resemble those reported for medium-dose (75-150 +micrograms) LSD experiences, including spatial distortions, visual and +auditory hallucinations, intense imagery with eyes closed, synaesthesia and +mood elevation. These effects, which occur mainly during the period of 1 to 4 +hours after ingestion, are typically followed by a period of alert calmness +which may last until the subject goes to sleep. + + High Dose, 200-500 Seeds (12 Subjects) + +In this range the first few hours may resemble the medium-dose effects +described above. However, there is usually a period during which the +subjective states are of a sort not describable in terms of images or +distortions, states characterized by loss of ego boundaries coupled with +feelings of euphoria and philosophical insight. These seem to parallel the +published descriptions of experiences with high doses (200-500 micrograms) of +LSD given in a supportive, therapeutic setting as reported by Sherwood et al. +(1962). + +All the subjects who had previous experience with LSD claimed the effects of +the seeds were similar to those of LSD. Transient nausea was the most +commonly reported side effect, beginning about one half hour after ingestion +and lasting a few minutes to several hours. Other reported side effects not +commonly found with LSD were a drowsiness or torpor (possibly due to a +glucoside also present in the seeds) and a coldness in the extremities +suggesting that the ergine content of the seeds may be causing some vascular +constriction. (If this is the case, there may be some danger of ergot +poisoning resulting from excessive dosages of the seeds.) The only untoward +psychic effect was a prolonged (eight hours) disassociative reaction which +was terminate with chlorpromazine [Thorazine]. The possibility of prolonged +adverse reactions to the psychological effects of the seeds is essentially +the same as with LSD, and the same precautions should be observed (Cohen & +Ditman, 1963). + +.............................. + +IPOMOEA.003 7-MAY-90 + +Additional Notes: +Ipomoea purpurea is sold as the "Heavenly Blue" variety of morning glory. +"Ipomoea tricolor" is the trade name used for that variety. It is identical +with the species of morning glory described above. + +The seeds must be chewed or ground in order to be effective. Soaking the +ground seeds in water for several hours, filtering out the grounds, +and then drinking only the water portion of the mixture can reduce +some of the stomach-upset symptoms if such occur. + +Unpleasant LSD and morning glory trips can be smoothed out or even +stopped by taking niacin (in the form of nicotinic acid, vitamin B-3 or +"niacin"). Vitamin C has been shown to reduce the incidence of paranoia and +prevent depletion of the vitamin from the adrenal glands during LSD trips. + +There have been reports that commercially available packets of morning +glory seeds from some distributors are coated with fungicides or +other chemicals to increase shelf life or discourage the practice +of eating them. Seeds from plants grown in one's own garden will +be safe as long as you do not spray them with insecticides. + +The last few notes about Niacin and Vitamin C are based on +a paperback edition of Hoffer & Osmonds "The Psychedelics" + +It's pretty clear that the latin names of this plant are somewhat +confused (which is typical). Ipomoea purpurea, Ipomoea tricolor, +Ipomoea violacea and Ipomoea rubro-caerulea are all the same plant. + +The other variety of morning glory, "Ololiuhqui" has at least two +Latin names as well: Rivea corymbosa, and Turbina corymbosa. + +.............................. + +"Recreational use of Ergoline Alkaloids from Argyreia Nervosa" +William E. Shawcross +Journal of Psychedelic Drugs Vol. 15(4) Oct-Dec 1983 + +CHEMISTRY AND EFFECT OF THE SEEDS +The Hawaiian baby woodrose entered the drug scene in 1965 with the +publication of a paper in "Science" entitled "Ergoline Alkaloids in Tropical +Wood Roses" by Hylin and Watson. The wide circulation of this journal assured +thorough dissemination of the information they presented. They wrote, "The +possible health and legal problems associated with the presence of similar +compounds in commercially cultivated plants led us to examine the ornamental +wood roses, Ipomoea tuberosa and Argyreia nervosa, both common Hawaiian crops +that have assumed commerical importance as components of [the] dried tropical +flower industry." Comparing the seeds of these two plants with those of the +morning glory varieties Pearly Gates and Heavenly Blue, they found the +following yield of alkaloids (mg of alkaloid/g of seed material): + + Heavenly Blue 0.813 + Pearly Gates 0.423 + I. tuberosa [None] + A. nervosa 3.050 + +The seed of A. nervosa is the best plant source of ergoline alkaloids +discovered; it contains approximately 3 mg of alkaloidal material per gram of +seed. Approximately one-eighth of this is lysergamide. + +Hylin and Watson found the major alkaloidal constituents in A. nervosa seeds to +be ergine (780 mcg/g of fresh seed) and isoergine and penniclavine (555 mcg). + +[Note: Argyreia nervosa has NO history of shamanic use as a hallucinogen] + +This is an excerpt from the article cited. +There's no record of Argyreia being used as an hallucinogen in +India, but it was used externally as some kind of skin medicine. +There's been speculation that Argyreia might have been a component +of "Soma", but there's no evidence for that, apparently. +Because there's not a long history of human usage of Argyreia, +it may be that there are glycosides not mentioned here that +take effect at higher doses or might cause stomach upset, tachycardia +etc. The article mentioned intestinal complaints in one or two +cases at higher experimental doses. + + + + + +****************************** + +CHEMISTRY: + +lysergic acid diethylamide _is_ lysergic acid diethylamide (or... +N,N-diethyl-D-lysergamide or... +9,10-Didehydo-N,N-diethyl-6-methylergoline-8B-carboxamide). + +Only one stereoisomer (the d-) is psychoactive. Thus, racemic (l/d 50-50 mix) +lsd shows half the potency of the dextro form. In synthesis it is possible +to recover the l-form for the lysergic acid. + +Lysergic Acid Diethylamide is LSD rather than LAD because the German word +for acid is saeure (sp). + + LSD-25 Lysergic acid + + O CH2-CH3 O + || / || + || / || + -C--N C---OH + | \ | + | \ | + |___ CH2-CH3 |___ + / \ / + / \ / + << N---CH3 << N---CH3 + \ / \ / + \____/ \____/ + / \ / + / \ / + < > < > + // \ / // \ / + // \_____/ // \_____/ + | || || | || || + | || || | || || + | || || | || || + \ /\ / \ /\ / + \ / \ / \ / \ / + N N + H H + +Ergot is a product of the fungus Claviceps purpurea. The bio-active +ingredients of ergot are all derivatives of lysergic acid. LSD is a +semisynthetic derivative of lysergic acid. Thus LSD is an +"ergot"-like substance. + +****************************** + + +MECHANISM OF ACTION: + +(Note: the mechanism of action of LSD and other psychedelics is uncertain.) + +>From a chapter titled Hallucinogens and Other Psychotomimetics: Biological +Mechanisms by S.J.Watson + +"The current thesis of the effect of indole hallucinogens on +5-hydroxytrypamine might be stated as follows: LSD acts to preferentially +inhibit serotonergic cell firing and seems to spare postsynaptic serotnergic +receptors. This preference is shared by other simillar hallucinogens but in +a limited fashion. Nonhallucinogenic analogs of LSD show no preference. +These results suggest that there are two different steric conformation of +serotonergic receptors, one of which has higher affinity for LSD than the +other. In general, 5-ht is an inhibitory transmitter; thus, when its +activity is decreased, the next neuron in the chain is freed from inhibition +and becomes more active. Since serotnergic systems appear to be intimately +involved int eh control of sensation, sleep, attention, and mood, it may be +possible to explain the actions of LSD and other hallucinogens by their +disinhibition of these critical systems. + +There is also evidence for interaction with dopaminergic systems. + +.............................. + +LSD acts as a 5HT autoreceptor agonist in the raphe nucleus. These +autoreceptors are typically considered to be 5HT1As. It also acts as a 5HT2 +agonist, which is thought to be the main site of hallucinogenic activity. +It's probably best called a a mixed 5HT2/5HT1 receptor partial agonist. + +I don't know of its effects on dopamine. Wouldn't be surprised if it has +'em; the systems aren't really functionally separable. The DA effects +wouldn't be necessary for hallucinogenic activity, I'd bet. + +.............................. + +>"If there's no documentation, you can't tell bugs from features." ---C.P. + +****************************** + +RELATED COMPOUNDS: + + + +Related compounds are the indole hallucinogens including DMT +(dimethyl-tryptamine), DET (diethyl-), etc.; psilocybin; lysergic acid. DMT +is very fast acting, lasting less than an hour. Psilocybin, found in +hallucinogenic (aka magic or mexican) mushrooms, has effects similar to LSD +but they work for approximately half the duration. These are all indole +derivatives like the neurotransmitter serotonin, 5-hydroxy-tryptamine. +"Indole" is the name of the 6-carbon ring attached to the 5-ring containing +a nitrogen. The lysergic acid molecule contains an indole structure plus +additional rings. + +LSD's two ethyl groups hanging off the amine may be replaced with +other carbon chains for compounds with different durations, potencies, +and effects. + +While LSD is semi-synthetic, DMT and psilocybin are found in nature. +See the sections on BOTANY and ANTHROPOLOGY for info on related +natural (plant) compounds and their uses. + +.............................. + + 1) DMT, DET, psylocin, psylocybin, : The mushroom psylocybin cubensis +contains all four of these indole derivatives, as well as others. DMT is +dimethyltryptamine, an indole derivative which has functionalized at the 3 +position with the dimethyl ethylamine group. It is a close relative to the +amino acid, tryptophan, which until recently was available in bulk at +vitamin shops, until some jerk poisoned himself by taking a wonga dose of +it. [Actually it may have been a single toxic batch mistakenly produced in +Japan.] A prep came out in 1984 for LSD using l--tryptophan as the +precursor, so this may have facilitated the government's pullin it from the +shelves. I can't find tryptophan anywhere, now, and I've tried, bud. + DMT, and it's brother DET (diethyltryptamine), have no oral activity, +so have to be smoked. They stink like fish oil when lit, though. Both have +hallucinogenic effects within 2-3 minutes of toking, wand while DMT lasts +for only a half hour, DET is a smoother, more euphoric high, lasting twice +as long. DET has effects similar to psylocybin. + Psylocybin is DMT which has a functional group, phosphoryloxy-, at the +4 position on the indole ring. This group is immediately converted to +hydroxyl- as soon as the stuff hits your stomach to give the cousin, +psylocin. In preparing the drug, then, it is not necessary to proceed beyond +the psylocin. + DMT and DET are easily derived from many indole derivatives, the +easiest of which is indole-3-acetic acid. I've done this reaction and it +stinks to high heaven of indole gunge, skatoles (methylindoles), and +indenes. Bad news if you want to make it at home, because the stench is +pervasive. Other derivatives, using phenyl or butyl groups have been +reported as having oral activity, so it is not necessary to smoke the stuff. +Doses run at about a hundred mgs for smoked drug, while psylocin is orally +active at about 5 mgs. + For a good reference work on these compounds, their preps, and effects, +see Michael Valentine Smith's "Psychedelic Chemistry," publisher unknown. + + + Your Friendly Neighborhood Chemical + Dude, + St. Theo + + +.............................. + + DMT + CH + / 3 + // \--- --- CH CH N + || || || 2 2 + \ //\ / CH + N 3 + H + + + +****************************** + +MANUFACTURE: + +Forget it. Precursors (ergot alkaloids, used medicinally for migraines and +ob/gyn due to their vasoconstrictive effects) are closely watched. (They +are obtained through commercially cultured ergot fungus; one could +theoretically extract lsyergic amides from morning glory or Hawaiian wood +rose seeds.) (Though there are routes to synthesize lysergic acid from +"scratch", these are complicated also.) Other typically needed chemicals +are very dangerous. Serious experience in organic chemistry lab would be +necessary. If you have to ask where to find the recipes, you don't know +enough about chemistry to try it. (For the curious: the _Anarchists +Cookbook_ is a bad place to start. _Psychedelic Chemistry_ is better, the +patent office or chem. lit. better.) And you'll probably trip during +manufacture if you actually succeed. Its easier and safer to buy it on the +black market. + + +****************************** + +DRUG TESTING: + +No risk. Its not looked for, hard to find, and transient. + +.............................. + + +"A maximum concentration of 2-8 ng/ml [Plasma concentration of LSD] + was reached 1.0-1.25 h after an oral dose of 160 ug. + ...[A] value of 2.9 h for the elimination half-life of LSD from + plasma [was reached]. + [Upshall, D.G., Wailling, D.G.: The determination of LSD in + human plasma following oral administration. + Clinica Chimica Acta 36, 67-73 (1972)] + +Second of all, LSD and its metabolites are detectable in the urine +for much longer than one hour. + +"LSD and its metabolites were still detectable in human urine for + as long as 4 days after the ingestion of 0.2 mg of the drug. + [Faed, E.M., McLeod, W.R.: A urine screening test of lysergide. + Journal of Chromatographic Science. 11, 4-6 (1973)] + +Note that standard, cheap initial drug screening does not use +chromatography or mass-spectrometry, and does not look for LSD. + +.............................. + +Spinal taps are not particularly useful (cerebro-spinal fluid doesn't +concentrate LSD or metabolites) and are never done under any +circumstances: they are painful and dangerous. + +.............................. + + +You might want to mention that Abbie Hoffman's _Steal This Urine Test_ +has a table which claims lsd is detectable for 40 days. I'm almost sure +this was a typo. + +.............................. + + +> 1] How long can LSD be detected in the body? + +This varies by the test being used, the detection limit placed on the test, +the point of collection and type of the sample fluid, the amount of LSD that +was taken, and the individual in question. + +Assuming the testers are using an RIA screening test with the cutoff set at +0.1 ng/ml and assuming that the user has recently emptied their bladder, +then the detection limit for one hit (100 ug) is normally around 30 hours. +Each doubling of the initial amount will add about 5 hours. Thus taking 8 +hits will leave a user vulnerable for approximately 2 days. (NOTE: This is +based on the data in [7]) + +> 2] What exact form of test can be used to detect LSD in the body? There +are a number of tests which can be used to detect LSD in the body. + +Abuscreen, a product of Roche Diagnostic Systems, is a series of +RadioImmunoAssay (RIA) tests, one of which is used to detect LSD and its +metabolites in whole blood, serum (blood), urine and stomach contents [1]. +RIA can in theory be used to detect quantities as small as 0.020 nanograms +(ng) per milliliter (ml) of sample [2]. Laboratory tests have shown that +RIA results are accurate down to at least 0.1 ng/ml [3]. The manufacturer +recommends limiting the cutoff to 0.5 ng/ml. + +EMIT, a product of Syva Corporation, is another series of tests, one of +which can be used to detect LSD and its metabolites in serum and urine. +EMIT stands for Enzyme Multiplied Immunoassay Technique. + +Both EMIT and Abuscreen are "positive/negative" response tests (much like +pregnancy tests) which require periodic equipment calibration and consume +chemicals for each test performed. A basic battery of tests costs approx. +$15-$25 per person [4]. The basic tests (recommended by NIDA) include +marijuana, cocaine, amphetamines, opiates, and phencyclidine (PCP). +Normally, unless an (employer) specifically requests the test, an LSD assay +is not run. + +Both Roche and Syva recommend confirmation of positive results by using a +different test. The usual method of confirming positive results is some +form of chromatography. These include High Performance Thin Layer +Chromatography (HPTLC)[3], and different forms of Gas Chromatography/Mass +Spectrometry (GC/MS)[5][6][7][8][9]. HPTLC and GC/MS can be used to give +quantitative results as opposed to the Boolean results from EMIT or +Abuscreen. Laboratory tests have shown that GC/MS test for LSD in urine[6] +and blood[7] can be accurate down to 0.1 ng/ml. The cost for confirmation +of a positive screening test is approximately $50-60. + +Positive results to either EMIT and RIA are held to be "probable cause" by +U.S. courts. GC/MS results are held to be "proof" by U.S. courts. + +> I am asking for an actual text message containing a short, precise > +description of each test, + +Immunoassays chemicals are created by injecting animals (rabbits, sheep, +donkey, etc) with the drug to be tested for and an albumin which force the +animal to produce antibodies. The antibodies are then removed from the +animal, purified and bottled. In RIA tests, the antibodies are then added +to the fluid sample with a radioactively labeled chemical. Any of the drug +(or similar chemicals) found in a sample that is being tested will react +with this glop and by measuring the radioactivity, the amount of drugs can +be determined [2][10]. + +> 3] How can such a test be beaten? + +While there is some literature on adulterating urine samples to produce +false negative results [11], there has been little written that applies +specifically to the LSD screening tests. + +I would suggest you read the article posted by Paul Hager paying particular +attention to the warning about water intoxication [12]: +In <1991May7.141615.16477@news.cs.indiana.edu> hagerp@iuvax.cs.indiana.edu wrote ++ Recommended: "Dealing With Urine Tests on Short Notice" ++ by Dale Gieringer, California NORML ++ ++ Most folks recommend that people hydrate themselves -- the idea ++ being that by drinking water and taking a diuretic that will ++ promote water loss, the urine will be very dilute and THC metabolite ++ content from "tomatoe" consumption will drop below the 100 ng/ml ++ threshold that defines a "positive". ++ ++ Mr. Gieringer recommends that, the day before the test, the ++ person drink lots of water. I would amend this to, drink your ++ normal "8 glasses" plus a few more. Don't get carried away with ++ drinking water -- there is such a thing as "water intoxication" ++ which can result in brain swelling and other nasties so don't ++ chug-a-lug a gallon of water just before the test. After ++ hydrating, and a little before the test, drink some more water ++ and use a diuretic (coffee is a weak diuretic). Urinate to ++ flush the bladder -- the first urination of the day is the ++ one most charged with metabolites. The pamphlet quotes from ++ a _High Times_ article, "How to Beat a Drug Test": ++ ++ Take an 80 mg dose of the prescription diuretic Lasix ++ (furosemide); take a hefty drink of water; piss two ++ or three times; then take the test. ++ ++ Some caution is to be exercised in taking diuretics. Consult ++ your physician. ++ ++ Mr. Gieringer also suggests that the clear, watery urine that ++ results from the above procedure is sometimes suspicious. He ++ recommends taking 50-100 mg of vitamin B2 which will color ++ urine yellow for a couple of hours. Vitamin C does not produce ++ this effect -- contrary to rumor. ++ ++ For more information, I'd suggest contacting California NORML ++ directly at (415) 563-5858. They are located in San Francisco. ++ It is also possible that Mr. Gieringer will respond directly ++ via his canorml account. + +> I am asking for ...[a description]... of each thing that LSD leaves behind +> that can be detected, and of each method used to beat each test. + +The immunsoassay tests vary in their specificity. Some display a relatively +low cross-reactivity[13], others a high cross-reactivity[14]. The exact +metabolites of LSD in humans have not been fully determined yet, though +animal studies have been done. The only verified human metabolite I could +find in the literature was N-demethyl-LSD[6] but I did not check all the +references. + +FOOTNOTES: +[1] +Altunkaya, D; Smith R.N. +"Evaluation of a commercial radioimmunoassay kit for the detection of +lysergide (LSD) in serum, whole blood, urine, and stomach contents" +Forensic Science International. v47n2, September 1990, p113-21. +[2] +Taunton-Rigby, A.; Sher, S.E.; Kelley, P.R. +"Lysergic Acid Diethylamide: Radioimmunoassay" +Science. v181, July 13 1973, p165-6. +[3] +McCarron, M.M.; Walberg, C.B.; Baselt, R.C. +"Confirmation of LSD intoxication by analysis of serum and urine." +Journal of Analytical Toxicology. v14n3, May-June 1990, p165-7. +[4] +Berg, E. +"Drug-testing methods: what you should know." +Safety & Health. v142n6, Dec 1990, p52-6. +[5] +Lim, H.K.; Andrenyak, D.; Francom, P.; Bridges, R.R.; Foltz, R.L. +"Determination of LSD in urine by capillary column gas chromatography +and electron impact mass spectrometry." +Journal of Analytical Toxicology. v12n1, Jan-Feb 1988, p1-8. +[6] +Lim, H.K.; Andrenyak, D.; Francom, P. +"Quantification of LSD and N-demethyl-LSD in urine by gas chromatography/ +resonance electron capture ionization mass spectrometry." +Analytical Chemistry. v60, July 15 1988, p1420-25. +[7] +Papac, D.I.; Foltz, R.L. +"Measurement of lysergic acid dietylamide (LSD) in human plasma by gas +chromatography/negative ion chemical ionization mass spectrometry." +Journal of Analytical Toxicology. v14n3, May-June 1990, p189-90. +[8] +Paul, B.D.; Mitchell J.M.; Burbage, R.; Moy, M; Sroka, R. +"Gas chromatographic-electron-impact mass fragmentometric determination +of lysergic acid diethylamide in urine." +Journal of Chromatography. v529n1, July 13, 1990, p103-12. +[9] +Blum, L.M.; Carenzo, E.F.; Rieders, F. +"Determination of lysergic acid diethylamide (LSD) in urine by instrumental +high-performance thin-layer chromatography." +Journal of Analytical Toxicology. v14n5, Sep-Oct 1990, p285-7. +[10] +Ratcliffe, W.A.; Fletcher, S.M.; Moffat, A.C.; et. al. +"Radioimmunoassay of Lysergic Acid Diethylamide (LSD) in serum and urine +by using antisera of different specificities." +Clinical Chemistry. v23n2, Feb 1977, p169-74. +[11] +Cody, J.T.; Schwarzhoff, R.H. +"Impact of adulterants on RIA analysis of urine for drugs of abuse." +Journal of Analytical Toxicology. v13n5, Sep-Oct 1989, p277-84. +[12] +Klonoff, D.C. +"Acute water intoxication as a complication of urine drug testing in the +workplace." +Journal of the American Medical Association. v265n1, Jan 2 1991, p84-6. +[13] +Christie J.; White, M.W.; Wiles, J.M. +"A chromatographic method for the detection of LSD in biological liquids." +Journal of Chromatography. v120n2, May 26, 1976, p496-501. +[14] +Twitchet, P.J.; Fletcher, S.M.; Sullivan, A.T.; Moffat, A.C. +"Analysis of LSD in human body fluids by high-performance liquid chromatography, +fluorescence spectroscopy and radioimmunoassay." +J. Chromatogr. v150n1, March 11 1978, p73-84. + +Sorry this was so long but I thought it deserved it :-) +Enjoy a "referenced" article. +Tim Basher + +.............................. + +There were rumors going around that LSD could be detected +by drug tests fo thirty days. I think this reference and +abstract makes it clear that it is probably 4 days, max. +(see the end of the abstract) + + IDNUM 03319915 + TYPE Journal paper + DATE 880715 + AUTHOR Heng Keang Lim; Andrenyak, D.; Francom, P.; Foltz, R.L.; Jones, R.T. + Center for Human Toxicology, Utah Univ., Salt Lake City, UT, USA + TITLE Quantification of LSD and N-demethyl-LSD in urine by gas + chromatography/resonance electron capture ionization mass + spectrometry + SOURCE Analytical Chemistry; vol.60, no.14; 15 July 1988; pp. 1420-5 + SUBJECT chromatography; electron capture; mass spectroscopic chemical + analysis; organic compounds; quantification; gas chromatography; + resonance electron capture ionisation mass spectrometry; LSD; + N-demethyl-LSD; urine; lysergic acid diethylamide; human; in vitro; + in vivo; aromatic hydroxylation; drug; metabolite; + N-tri-fluoroacetyl derivatives; calibration curves; urinary + concentrations; adult volunteer; excretion; elimination half-lives; + 4 to 6 hrs; 8 to 10 hrs + Numerical data: time 1.4E+04 to 2.2E+04 s; time 2.9E+04 to 3.6E+04 s + Class codes: A8280M; A8280B; A3470 + CODEN ANCHAM + ABSTRACT Demethylation of lysergic acid diethylamide (LSD) in the human has + been demonstrated, both in vitro and in vivo, and aromatic + hydroxylation at positions 13 and 14 has been tentatively + identified. A gas chromatography/resonance electron capture + ionization mass spectrometry (GC/MS) assay for LSD and + N-demethyl-LSD in urine has been developed, in which the drug and + its metabolite are converted to their N-tri-fluoroacetyl derivatives + prior to GC/MS analysis. Linear and reproducible calibration curves + have been obtained for LSD concentrations from 0.05 to 5.0 ng/mL, + and for N-demethyl-LSD concentrations from 0.03 to 5.0 ng/mL. The + assay was used to determine the urinary concentrations of LSD and + N-demethyl-LSD following administration of a single oral dose of the + drug (1 mu g/kg) to an adult volunteer. The rates of excretion of + LSD and N-demethyl-LSD reached maxima in urine collected at time + intervals of 4-6 and 8-10 h after administration, respectively. The + elimination half-lives for LSD and N-demethyl-LSD were 3.6 and 10.0 + h, respectively + MISCELLANEOUS + Treatment: experimental + Anal. Chem. (USA) + Abstract number(s): A89037987 + ISSN: 0003-2700 + Refs: 15 + +****************************** + +LEGAL SCHEDULING: + +Class I, "no medical use" --- mostly for political reasons, as it was +and is used in psychotherapy. (Current use is in Switzerland.) + + +****************************** + +SET and SETTING: + +"SET" is the expectations a person brings with them. "Setting" is the +environment that a person is in. Set includes expectations about the +drug's actions and how the person will react. Setting includes the +social and physical conditions. For LSD and the hallucinogen-type +drug more than other psychoactives, set and setting are very important +in determining the nature of the experience. These factors make the +difference between, e.g., the experiences of someone taking the drug +for enhancement at a concert, for psychotherapy in an doctor's office, +in a religious context, or in the outdoors for an aesthetic +experience. For best results, one should take LSD only with people +one trusts in safe, comfortable surroundings, free of everyday +intrusions. Tripping alone is a very risky thing to do, that +inexperienced people should avoid. + +****************************** + +STORAGE: + +First, note that LSD is a fairly stable organic molecule, no more or +less fragile than other molecules with comparable structures. + +The main factors to be concerned with are moisture (due to leaching +and facilitated chemical reactions in the presense of moisture), +oxygen, light, and temperature. Reaction rates typically depend upon +temperature exponentially. These factors basically apply to all +organic compounds. + +Sealing in AL foil in a cool dark place is fine. Some recommend +refrigeration, but be careful about nosy guests, condensation, and frost. +Multiple, redundant seals are suggested, eg., paper in metal foil in +plastic in a metal candy tin which has been taped shut. Should last +at least a presidential term. + +Wallets are contraindicated as storage locations due to sweat. + +****************************** + +SYNERGIES, BAD COMBINATIONS: + +Smoking cannabis products considerably increases the effects, +increasing the visuals and also possibly increasing the cognitive and +linguistic disorders. As the effects of LSD wear off, marijuana may +bring them back, and also ease the jitteriness some dislike. Nitrous +oxide goes well with LSD, though one should be extra careful (not to +suffocate or fall down) with the nitrous because of the effects of the +LSD. MDA & cousins can go well, but people on these drugs should not +take LSD unless they are familiar with the latter's effects. + +Alcohol's effects are largely overwhelmed by LSD, and they act in opposite +ways: alcohol being a depressant and LSD being a (hyper)stimulant. +Generally mixing stimulants and sedatives is counterproductive. + +MAO inhibitors ??? +Amphetamines and cocaine ??? + +****************************** + +SYNTHESIS: + +Don't try it, too difficult and risky both physically and +legally. Precursor medical drugs (ob/gyn and migraine ergot +alkaloids) are watched. + +****************************** + + + +X-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-X + Another file downloaded from: The NIRVANAnet(tm) Seven + + & the Temple of the Screaming Electron Taipan Enigma 510/935-5845 + Burn This Flag Zardoz 408/363-9766 + realitycheck Poindexter Fortran 510/527-1662 + Lies Unlimited Mick Freen 801/278-2699 + The New Dork Sublime Biffnix 415/864-DORK + The Shrine Rif Raf 206/794-6674 + Planet Mirth Simon Jester 510/786-6560 + + "Raw Data for Raw Nerves" +X-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-X diff --git a/textfiles.com/drugs/m7 b/textfiles.com/drugs/m7 new file mode 100644 index 00000000..9e553dc6 --- /dev/null +++ b/textfiles.com/drugs/m7 @@ -0,0 +1,265 @@ + MARIJUANA MYTHS + by Paul Hager + Hoosier Cannabis Re-legalization Coalition + +1. Marijuana causes brain damage + + The most celebrated study that claims to show brain damage +is the rhesus monkey study of Dr. Robert Heath, done in the late +1970s. This study was reviewed by a distinguished panel of +scientists sponsored by the Institute of Medicine and the +National Academy of Sciences. Their results were published under +the title, Marijuana and Health in 1982. Heath's work was +sharply criticized for its insufficient sample size (only four +monkeys), its failure to control experimental bias, and the +misidentification of normal monkey brain structure as "damaged". +Actual studies of human populations of marijuana users have shown +no evidence of brain damage. For example, two studies from 1977, +published in the Journal of the American Medical Association +(JAMA) showed no evidence of brain damage in heavy users of +marijuana. That same year, the American Medical Association +(AMA) officially came out in favor of decriminalizing marijuana. +That's not the sort of thing you'd expect if the AMA thought +marijuana damaged the brain. + +2. Marijuana damages the reproductive system + + This claim is based chiefly on the work of Dr. Gabriel +Nahas, who experimented with tissue (cells) isolated in petri +dishes, and with researchers who dosed animals with near-lethal +amounts of cannabinoids (i.e., the intoxicating part of +marijuana). Nahas' generalizations from his petri dishes to +human beings have been rejected by the scientific community as +being invalid. In the case of the animal experiments, the +animals that survived their ordeal returned to normal within 30 +days of the end of the experiment. Studies of actual human +populations have failed to demonstrate that marijuana adversely +affects the reproductive system. + +3. Marijuana is a "gateway" drug -- it leads to hard drugs + + This is one of the more persistent myths. A real world +example of what happens when marijuana is readily available can +be found in Holland. The Dutch functionally decriminalized +marijuana in the 1970s. Since then, hard drug use -- heroin and +cocaine -- have DECLINED substantially. Even use of marijuana +has declined. If marijuana really were a gateway drug, one would +have expected use of hard drugs to have gone up. Actual studies +of hard drug "addicts" reveal that they start with alcohol or +tobacco more frequently than marijuana. + +4. Marijuana suppresses the immune system + + Like the studies claiming to show damage to the reproductive +system, this myth is based on studies where animals were given +extremely high doses of cannabinoids. These results have never +been duplicated in human beings. Interestingly, two studies done +in 1978 and one done in 1988 showed that hashish and marijuana +may have actually stimulated the immune system in the people +studied. + +5. Marijuana is much more dangerous than tobacco + + Smoked marijuana contains more carcinogens than does an +equivalent amount of tobacco (1.5 to 3 times). Marijuana, +however, unlike tobacco, actually dilates (enlarges) the air +passages in the lungs which promotes self-cleaning. This is one +reason why cannabis has been found useful in the past in treating +asthmatics. It should be remembered that a heavy tobacco smoker +consumes much more tobacco than a heavy marijuana smoker consumes +marijuana. Two other factors are important. The first is that +paraphernalia laws directed against marijuana users make it +difficult to smoke safely. These laws make water pipes and +bongs, which filter some of the carcinogens out of the smoke, +illegal and, hence, unavailable. The second is that, if +marijuana were legal, it would be more economical to have +cannabis drinks like bhang (a traditional drink in the Middle +East) or tea which are totally non-carcinogenic. This is in +stark contrast with "smokeless" tobacco products like snuff which +can cause cancer of the mouth and throat. Nicotine itself is +very toxic in even small quantities. In contrast, the +cannabinoids are relatively non-toxic. When all of these facts +are taken together, it can be clearly seen that the reverse is +true: marijuana is much SAFER than tobacco. + +6. Legal marijuana would cause carnage on the highways + + Although marijuana, when used to intoxication, does impair +performance in a manner similar to alcohol, actual studies of the +effect of marijuana on the automobile accident rate suggest that +it poses LESS of a hazard than alcohol. When a random sample of +fatal accident victims was studied, it was initially found that +marijuana was associated with RELATIVELY as many accidents as +alcohol. In other words, the number of accident victims +intoxicated on marijuana relative to the number of marijuana +users in society gave a ratio similar to that for accident +victims intoxicated on alcohol relative to the total number of +alcohol users. However, a closer examination of the victims +revealed that around 85% of the people intoxicated on marijuana +WERE ALSO INTOXICATED ON ALCOHOL. For people only intoxicated on +marijuana, the rate was much lower than for alcohol alone. This +would suggest that legal marijuana would not pose as serious a +hazard as legal alcohol. + + NOTE: We of the HCRC believe that DUI laws pertaining to +driving under the influence of alcohol should apply to driving +under the influence of marijuana. We believe in the RESPONSIBLE +USE of marijuana, NOT IRRESPONSIBLE ABUSE. + +7. Marijuana "flattens" human brainwaves + + This is an out-and-out lie perpetrated by the Partnership +for a Drug-Free America. A few years ago, they ran a TV ad that +purported to show, first, a normal human brainwave, and second, a +flat brainwave from a 14-year-old "on marijuana". When +researchers called up the TV networks to complain about this +commercial, the Partnership had to pull it from the air. It +seems that the Partnership faked the flat "marijuana brainwave". +In reality, marijuana has the effect of slightly INCREASING alpha +wave activity. Alpha waves are associated with meditative and +relaxed states which are, in turn, often associated with human +creativity. + +8. Marijuana impairs short-term memory + + This is true but misleading. When one is intoxicated on +alcohol, one's motor control is affected. When one is +intoxicated on marijuana, one's concentration is affected. Any +impairment of short-term memory disappears when one is no longer +intoxicated. Often, the short-term memory effect is paired with +a reference to Dr. Heath's poor rhesus monkeys to imply that the +condition is permanent. + +9. Marijuana lingers in the body like DDT + + This is also true but misleading. Cannabinoids are fat +soluble as are innumerable nutrients and, yes, some poisons like +DDT. For example, the essential nutrient, Vitamin A, is fat +soluble but one never hears people who favor marijuana +prohibition making this comparison. + +10. There are over a thousand chemicals in marijuana smoke + + Again, true but misleading. The 31 August 1990 issue of the +magazine Science notes that of the over 800 volatile chemicals +present in roasted COFFEE, only 21 have actually been tested on +animals and 16 of these cause cancer in rodents. Yet, coffee +remains legal and is generally considered fairly safe. + +11. No one has ever died of a marijuana overdose + + This is true. It was put in to see if you are paying +attention. Animal tests have revealed that extremely high doses +of cannabinoids are needed to have lethal effect. This has led +scientists to conclude that the ratio of the amount of +cannabinoids necessary to get a person intoxicated (i.e., stoned) +relative to the amount necessary to kill them is 1 to 40,000. In +other words, to overdose, you would have to consume 40,000 times +as much marijuana as you needed to get stoned. In contrast, the +ratio for alcohol varies between 1 to 4 and 1 to 10. It is easy +to see how upwards of 5000 people die from alcohol overdoses +every year and no one EVER dies of marijuana overdoses. + +Check us out + + We believe that the truth is our strongest weapon. To date, +the prohibitionists have refused to meet us in public debate: +they fear the truth and know that they stand to lose in any +direct confrontation. They cower behind a wall of myths, lies, +and half truths. In the battles that lie ahead we will try to +flush the prohibitionists into the open. In order to be +successful in this goal, we will need to batter down the myths +and lies by giving our message the widest possible distribution. + + Check us out. Listen to our Truth Squad, check our sources, +and ask us the tough questions. Examine our claims with a +skeptical, but open, mind. We feel that after looking at the +facts you will find it very hard to side with the prohibitionists +ever again. + + We're looking for allies, declared or undeclared. Getting +the message out costs money. Our opponents dispose of literally +hundreds-of-millions of dollars. If you'd like to quietly donate +to the cause, send your contributions to the Hoosier Cannabis +Re-legalization Coalition at P.O. Box 5325, Bloomington, IN +47407. If you'd like to help in a more direct way contact me, +Paul Hager, at (812) 333-1384. Our meetings are open to the +public and we welcome new members. Contact us for more +information. + +Sources + +1) Marijuana and Health, Institute of Medicine, National + Academy of Sciences, 1982. Note: the Committee on Substance + Abuse and Habitual Behavior of the "Marijuana and Health" + study had its part of the final report suppressed when it + reviewed the evidence and recommended that possession of + small amounts of marijuana should no longer be a crime (TIME + magazine, July 19, 1982). The two JAMA studies are: Co, + B.T., Goodwin, D.W., Gado, M., Mikhael, M., and Hill, S.Y.: + "Absence of cerebral atrophy in chronic cannabis users", + JAMA, 237:1229-1230, 1977; and, Kuehnle, J., Mendelson, + J.H., Davis, K.R., and New, P.F.J.: "Computed tomographic + examination of heavy marijuana smokers", JAMA, 237:1231- + 1232, 1977. + +2) See Marijuana and Health, ibid., for information on this + research. See also, Marijuana Reconsidered (1978) by Dr. + Lester Grinspoon. + +3) See "A Comparison of Marijuana Users and Non-users" by + Norman Zinberg and Andrew Weil (1971). This showed a + negative correlation between use of marijuana and use of + alcohol. A recent article about the Dutch experience is + written up in "The Economics of Legalizing Drugs", by + Richard J. Dennis, The Atlantic Monthly, Vol 266, No. 5, Nov + 1990, p. 130. + +4) See a review of studies and their methodology in "Marijuana + and Immunity", Journal of Psychoactive Drugs, Vol 20(1), + Jan-Mar 1988. Studies showing stimulation of the immune + system: Kaklamani, et al., "Hashish smoking and T- + lymphocytes", 1978; Kalofoutis et al., "The significance of + lymphocyte lipid changes after smoking hashish", 1978. The + 1988 study: Wallace, J.M., Tashkin, D.P., Oishi, J.S., + Barbers, R.G., "Peripheral Blood Lymphocyte Subpopulations + and Mitogen Responsiveness in Tobacco and Marijuana + Smokers", 1988, Journal of Psychoactive Drugs, ibid. + +5) For current information on cannabis drinks see Working Men + and Ganja: Marijuana Use in Rural Jamaica by M. C. Dreher, + Institute for the Study of Human Issues, 1982, ISBN 0-89727- + 025-8. For information on cannabis and actual cancer risk, + see Marijuana and Health, ibid. + +6) For a survey of studies relating to cannabis and highway + accidents see "Marijuana, Driving and Accident Safety", by + Dale Gieringer, Journal of Psychoactive Drugs, ibid. + +7) For information about the Partnership ad, see Jack Herer's + book, The Emperor Wears No Clothes, 1990, p. 74. For + information on memory and the alpha brainwave enhancement + effect, see "Marijuana, Memory, and Perception", by R. L. + Dornbush, M.D., M. Fink, M.D., and A. M. Freedman, M.D., + presented at the 124th annual meeting of the American + Psychiatric Association, May 3-7, 1971. + +8) See Marijuana and Health, ibid. Also see "Marijuana, + Memory, and Perception", ibid. + +9) The fat solubility of cannabinoids and certain vitamins is + well known. See Marijuana and Health, ibid. For some + information on vitamin A, see "The A Team" in Scientific + American, Vol 264, No. 2, February 1991, p. 16. + +10) See "Too Many Rodent Carcinogens: Mitogenesis Increases + Mutagenesis", Bruce N. Ames and Lois Swirsky Gold, Science, + Vol 249, 31 August 1990, p. 971. + +11) Cannabis and alcohol toxicity is compared in Marijuana + Reconsidered, ibid., p. 227. Yearly alcohol overdoses was + taken from "Drug Prohibition in the United States: Costs, + Consequences, and Alternatives" by Ethan A. Nadelmann, + Science, Vol 245, 1 September 1989, p. 943. + + \ No newline at end of file diff --git a/textfiles.com/drugs/make.txt b/textfiles.com/drugs/make.txt new file mode 100644 index 00000000..61ee2b12 --- /dev/null +++ b/textfiles.com/drugs/make.txt @@ -0,0 +1,704 @@ + How to make LSD + + + + [All text used without permission + from the "Whole Drug Manufacturers Catalog" + Any typos are YOUR problem + For informational purposes only + I take NO responsibility for YOUR actions + Be careful --Ed.] + + + +NOTE: the techniques described herein are potentially dangerous. It +is highly recommended that the physical and chemical properties of +the reagents used and the reactions employed be given further study +by persons unfamiliar with them. For the layman to attempt these +procedures without first thoroughly preparing himself is to invite +almost certain disaster. The publishers therefore disclaim +responsibility for any damage or injury resulting from the improper +handling of the chemicals and techniques described, and strongly +urge all persons unqualified to perform the reactions to use +extraction rather than synthesis. + + + +#1: Kitchen chemistry + + Extraction of LSA (Lysergic acid amide) + from Morning Glory (Ipomosea Purpurea) seeds + or Hawaiian Baby Wood Rose (Argyreia Nervosa) seeds + + +NOTE: Morning Glory seeds may be coated with a toxic chemical by +the seed company in order to prevent ingestion. If a packet of +seeds contains coated seeds this fact should be stated on the +container. Soaking the seeds in warm water for 1/2 hour and +rinsing in a strainer should remove this coating. + +NOTE: while many varieties of morning glory contain the active LSA +(Lysergic acid amide), the yield varies greatly. Therefore, use +only Pearly Gates, Wedding Bells, and Heavenly Blue varieties for +best results. + + +Kitchen chemistry follows. + + +Materials: blender, funnel, filter paper, petroleum ether or + lighter fluid, methanol (wood alcohol), glass jar, + Pyrex baking dish + + + Grind Morning Glory or Hawaiian Baby Wood Rose seeds in a + blender until they are a fine powder, and spread them out to + dry. + Soak the powder with lighter fluid or petroleum ether. Cap + the container to avoid fumes, and don't smoke nearby, or + you'll be very sorry. + + In a well-ventilated area (neither ether nor lighter fluid are + good for you), filter the solution through filter paper in a + funnel. Discard the filtrate (the liquid). + + Dry mash completely. + + Soak mash in methanol (wood alcohol) for 2 days. Be careful +- + its vapors are poisonous and may be explosive. + + Filter, and save the filtrate. + + Soak the mash in methanol again a further 2 days. + + Filter. Discard the mash, save the filtrate. + + Pour both filtrates into a large, flat dish and evaporate in + the absence of direct sunlight. Sunlight will break down the + LSA. Preferably, perform ALL procedures in a cool, well- + ventilated place away from sunlight. + + After evaporation, a yellow gum will remain in the dish. + Scrape it up. + + To dose on the LSA, add some harmless filler (starch, flour, + milk sugar) to the gum until it is not sticky. Put in gelatin + capsules or take as is. 30 g Morning Glory seeds or 15 + Hawaiian Baby Woodrose seeds should make a goodly trip, so + adjust dosage accordingly. + + If you want to turn LSA into LSD, you can [see below], but + it's MUCH more difficult and VERY unsafe. + + + + +#2: Extraction of Lysergic Acid Amides + + + Start with domestic Morning Glory seeds, the young seeds of + the Hawaiian Baby Wood Rose, cultured ergot or naturally + occurring ergot compounds. + + +NOTE: Morning Glory seeds may be coated with a toxic chemical by +the seed company in order to prevent ingestion. If a packet of +seeds contains coated seeds this fact should be stated on the +container. Soaking the seeds in warm water for 1/2 hour and +rinsing in a strainer should remove this coating. + +NOTE: while many varieties of morning glory contain the active LSA +(Lysergic acid amide), the yield varies greatly. Therefore, use +only Pearly Gates, Wedding Bells, and Heavenly Blue varieties for +best results. + + + Reduce seed material to a fine powder in a blender, and spread + it out to dry. Grind again if not fine enough after the first + time due to dampness. + + Saturate powdered seed material with lighter fluid, naphtha or + ligroine. When completely saturated, it should have the + consistency of soup. + + Pour into a chromatography column and let it sit overnight. + + Remove the fatty oils from the material by dripping the + solvent through the column slowly, and testing the liquid that + comes through for fats by evaporating a drop on clean glass + until it leaves no greasy film. (It should take several + ounces of solvent for each ounce of seeds). + + Mix 9 volumes of chloroform with 1 volume of concentrated + ammonium hydroxide and shake in a separatory funnel. When it + settles, the chloroform layer will be on the bottom. Drain + the chloroform layer and discard the top layer. + + Drip the chloroform wash through the column and save the + extract. test continuously by evaporating a drop on clean + glass until it ceases to fluoresce. + + [It is NOT explicit in the source, but if extracting + from ergot, I would start with the ergot alkaloid base at + this point. --Ed.] + + Evaporate the chloroform extracts, and dissolve the residue in + the minimum amount of a 3% tartaric acid solution. If all the + residue doesn't dissolve, place it into suspension by shaking + vigorously. + + Color the solution with an acid base indicator, and titrate to + find the approximate number of moles of the alkaloid present. + + Transfer the solution to a separatory funnel, and wash the + other vessel with acid in order to get all the alkaloid out. + Pour the washings in the funnel also. + + Bring the pH up to make the solution basic by adding sodium + bicarbonate solution, and add an equal volume of chloroform. + + Shake thoroughly, let it settle, remove the bottom layer and + set aside. + Again add an equal portion of chloroform, shake, let settle + and remove bottom layer. + + Combine chloroform extracts (bottom layers) and evaporate. + + The residue remaining after evaporation is a semi-pure + concentrate of LSA (lysergic acid amide). The amide requires + some experimentation for dosage, but 1 mg of the concentrate + is a reasonable starting point. 1 mg LSA will produce effects + comparable to 100 micrograms of LSD. + + + + +#3: Ergot culture + + +NOTE: contact with ergot compounds can be dangerous. Only after a +basic understanding of the techniques employed in the handling of +dangerous or poisonous organisms is reached should one proceed with +the culture of ergot. + +The need for absolute sterility cannot be overstressed. Consult +any elementary text on bacteriology for the correct equipment and +procedures. Avoid prolonged contact with ergot compounds, as they +are poisonous and can be fatal. + + +A) Get a source for Claviceps Purpurea fungus + + + If no source can be found, you can make a field trip to obtain + it from rye or other cereal grasses. Rye grass is the best + choice. The ergot will appear as a blackish growth on the + tops of the rye where the seeds are. They are approximately + the same shape as the seeds and are referred to as "heads" or + "ergot". From these heads or ergot sprout the Claviceps + Purpurea fungi. + + They have long stems and bulbous heads when viewed under a + strong glass or microscope. It is these that must be removed + from the ergot, free from contamination, and used to inoculate + the culture material. + + +B) Make a culture medium + + + Combine the following ingredients in about 500 ml distilled + water in a 2 L small-neck flask: + + + Sucrose 100 g + + Chick pea meal 50 g + Calcium nitrate 1 g + Ca(NO3)2 + Monopotassium phosphate 0.25 g + KH2PO4 + Magnesium sulphate 0.25 g + MgSO4 + Potassium chloride 0.125 g + KCl + Ferrous sulphate heptahydrate 8.34 mg + FeSO47H20 + Zinc sulphate heptahydrate 3.44 mg + ZnSO47H20 + + + Add water to make up one liter + + Adjust to pH 4 with ammonia solution and citric acid + + Sterilize by autoclaving + + +C) Make a culture + + + Inoculate the sterilized medium with Claviceps Purpurea under + sterile conditions, stopper with sterilized cotton and + incubate for two weeks, periodically testing and maintaining + pH 4. After two weeks a surface culture can be seen on the + medium. Large-scale production of the fungus can now begin. + + +D) Large-scale production + + + Obtain several ordinary 1 gallon jugs. + + Place a two-hole stopper in the necks of the jugs. + + Fit a short (6 inch) tube in one hole, leaving two inches + above the stopper. Fit a short rubber tube to this. Fill a + small (500 ml) Erlenmeyer flask with a dilute solution of + sodium hypochlorite (NaClO). Extend a glass tube from the + rubber so the end is immersed in the hypochlorite. + + Fit a long glass tube in the other stopper hole. It must + reach near the bottom of the jug and have about two inches + showing above the stopper. Attach a rubber tube to the glass + tube and fit a short glass tube to the end of the rubber tube. + + + Fill a large glass tube (1" x 6") with sterile cotton and fit + one-hole stoppers in the ends. Fit the small glass tube in + the end of the rubber tube into one stopper of the large tube. + Fit another small glass tube into the other stopper. A rubber + tube is connected to this and attached to small air pump + (obtained from a tropical fish store). + + With this aeration equipment you can assure a supply of clean + air to the Claviceps Purpurea fungus while maintaining a + sterile environment inside the solution. + + Dismantle the aerators. Place all the glass tubes, rubber + tubes, stoppers and cotton in a paper bag, seal tightly with + wire staples and sterilize in an autoclave. + + Fill the 1-gallon jugs 2/3 to 3/4 full with the culture medium + and autoclave. + + While these things are being sterilized, homogenize in a + blender the culture already obtained and use it to inoculate + the material in the gallon jugs. The blender must be sterile. + + + EVERYTHING must be sterile. + + + Assemble the aerators. Start the pumps. A slow bubbling in + each jug will provide enough oxygen to the cultures. A single + pump may be connected to several filters. + + Let everything sit at room temperature (25 C) in a dark place + (never expose ergot alkaloids to bright light - they will + decompose) for a period of ten days. + + After ten days, adjust the culture to 1% ethanol using 95% + ethanol under sterile conditions. Maintain growth for another + two weeks. + + +E) Extract ergot alkaloids + + + After a total of 24 days growth period, the culture should be + considered mature. Make the culture acidic with tartaric acid + and homogenize in a blender for one hour. + + Adjust to pH 9 with ammonium hydroxide and extract with + benzene or chloroform/iso-butanol mixture. + + Extract again with alcoholic tartaric acid and evaporate in a + vacuum to dryness. + + The dry material is the salt (the tartaric acid salt, the + tartrate) of the ergot alkaloids, and is stored in this form + because the free basic material is too unstable and decomposes + readily in the presence of light, heat, moisture, and air. + + To recover the free base for extraction of the amide or + synthesis to LSD, make the tartrate basic with ammonia to pH + 9, extract with chloroform, and evaporate in vacuo. + + + + + +#4: Synthesis of LSD from ergot alkaloids or LSA + + (including sections on isomerization, separation, + purification & crystallization) + + +NOTE: the chemicals and reactions described below are potentially +dangerous even to an organic chemist in a well-equipped laboratory. + +The publishers therefore disclaim responsibility for any damage or +injury resulting from the improper handling of the chemicals and +techniques described, and strongly urge all persons unqualified to +perform the reactions to use instead the comparatively easier, +safer ergot culture and LSA extraction process. + + +A) Synthesis of LSD + (iso- & dextro-lysergic acid diethylamide) + + +PREPARATORY: obtain one red and one yellow photographic safety +light and one weak, long-wave ultraviolet light. These are used to +prevent the hydrolysis of lysergic acid compounds. + +NOTE: Aluminum foil must be used to cover the chemicals when light +is present. Rubber gloves must be worn; these compounds are +extremely poisonous. + + [The source implies but does not state that one may replace + "ergot alkaloid" in the following with the seed-derived semi- + pure LSA concentrate from #2. --Ed.] + + +USING YELLOW LIGHT: + + Place one volume of ergot alkaloid in a small roundbottom + flask. Add 2 volumes of anhydrous hydrazine and reflux for 30 + minutes, or the mixture may be heated in a sealed tube at 112 + Celsius for 30 minutes. If the reflux technique is used, + maintain atmospheric pressure by using an open container or + fractionating column. + + After heating/refluxing, add 1.5 volumes of water to the + mixture and boil gently for 15 minutes. After boiling is + complete, cool the mixture in a refrigerator until + solidification. The solid material obtained is iso-lysergic + acid hydrazide. + +USING RED LIGHT: + + Chill all chemicals (reagents) to be used to 0 Celsius. Place + an open flask in an ice bath. Add 100 ml concentrated + hydrochloric acid (chilled to 0 C). + + Quickly add 2.82 g of the lysergic acid hydrazide to the + hydrochloric acid, being careful to maintain a temperature of + 0 Celsius. + + Add 100 ml of a 0.1 N (1/10th Normal) solution of sodium + nitrite (chilled to 0 C) and stir vigorously for 3 minutes. + + Continue stirring at 0 Celsius and add dropwise 130 ml of the + hydrochloric acid. + + When the acid addition is complete, continue stirring for 5 + minutes, then neutralize the solution with sodium bicarbonate, + using a saturated water solution of the bicarbonate. + + Extract the solution with ether, remove the water layer, and + dissolve the gummy substance in ether. Add this to the ether + layer. + + Add 3 g of diethylamine for every 30 ml of the ether extract. + + Let this stand in the dark, and gradually warm up to 20 + Celsius for at least 24 hours. + + Evaporate this solution in a vacuum. + + The material remaining is a mixture of the inactive + iso-lysergic acid diethylamide and the active lysergic acid + diethylamide (LSD-25). The inactive isomer must now be + converted (isomerized) to the active isomer to greatly + increase the yield, since the inactive compound predominates + in this synthesis. + + + +B) Isomerization of iso-LSD into the active LSD-25 + + +USING THE RED LIGHT: + + Dissolve the synthesized material into the minimum amount of + ethyl alcohol. + + Mix a 4 Normal solution of potassium hydroxide in ethanol. + The amount of solution needed is twice the volume of the + iso-LSD/ethanol solution. + + Add the two solutions together and let the mixture sit for 4 + hours at room temperature. + + Neutralize the mixture with dilute hydrochloric acid, then + make it slightly basic with ammonium hydroxide. + + Extract the mixture with chloroform, sparate the chloroform + layer, and extract this four times with a 25% volume of water. + + Evaporate the chloroform in a vacuum. Discard the water + extracts. The material left after evaporation a mixture of + iso-LSD and LSD-25, the active LSD predominating. + + The mixture may now be separated by chromatography and the + iso-LSD again isomerized by the above process. + + + +C) Separation, purification & crystallization of LSD-25 + + +USING A DARKROOM: + + The material obtained from the isomerization process is now + dissolved in a solution prepared from 3 parts benzene/1 part + chloroform. Use 50 ml solvent per 1 gram LSD material. + + Mix a slurry basic alumina in benzene. Pack it into a 1 inch + chromatoghraphy column until it fills 6 inches. + + When the slurry settles, drain the benzene/chloroform down to + the level of the basic alumina, and carefully add an equal + amount of the LSD/solvent solution. + + +USING A WEAK, LONG-WAVE ULTRAVIOLET LIGHT: +(to follow the blue band only) + + Drain the solution through the column. The fastest-moving, + blue fluorescent band contains the LSD-25. Collect this + fraction and evaporate in a vacuum. The syrup remaining will + crystallize spontaneously, but slowly. Do not heat. + + Use the UV light only whe necessary to follow the blue band in + order to avoid decomposition of the compounds. + + Dissolve the syrup or crystal in tartaric acid solution and + recrystallize to form the stable end-product (dextro lysergic + acid diethylamide tartrate). + + The material remaining in the column may be removed with + methanol, evaporated in a vacuum, and recycled through the + isomerization and subsequent procedures by itself or combined + with fresh material. + Also, all leftover solutions and residues may be neutralized + with socium bicarbonate, evaporated in vacuo, and extracted + with ammoniacal chloroform, the extract evaporated to dryness, + and the residue reused. + + + + + +#5: Preparation of lysergic acid from the amide + + +NOTE: this synthesis is as difficult and dangerous as the rest, and +is of use only if using one of the following two LSD synthesis +methods, which require lysergic acid as the starting compound. The +lysergic acid amide obtained from the extract of ergot or seeds +need not be converted to the acid prior to its use in the synthesis +of LSD providing that the synthesis used is #4 given above, and +giving the starting material "ergot alkaloid". + + + Dissolve 10 g lysergic acid amide in 200 ml methanolic + potassium hydroxide solution. + + Remove the methanol by vacuum as soon as the amide is + dissolved. + + Dissolve the residue which is left into 200 ml of an 8% + solution of potassium hydroxide in water. + + Heat this mixture on a steam bath for 1 hour. + + Pass a steam of nitrogen gas through the flask during the + heating process. (The ammonia which is evolved in the gas + stream may be titrated with hydrochloric acid in order to + follow the reaction.) + + Neutralize the mixture with tartaric acid (neutral to congo + red) and run it through a filter paper. + + Extract the mixture with ether in a separatory funnel. Save + the water layer, discard the ether layer. + + Filter the solution through a filter paper and evaporate. + + Upon evaporation, dry crystals of lysergic acid will be + obtained. + + + + +#6: Synthesis of LSD + using lysergic acid + the quickest way to make pure LSD-25 +PREPARATORY: see #4 + +NOTE: The chemicals and techniques described are potentially +dangerous. It is highly recommended that the physical and chemical +properties of the reagents used be studied by those persons +unfamiliar with them before the synthesis is attempted. + + + +USING THE YELLOW LIGHT: + + 5.36 g of d-lysergic acid are suspended in 125 ml + acetonitrile, and the suspension is cooled to about -20 + Celsius in a bath of acetone cooled with dry ice. + + To the suspension is added a cold (-20 C) solution of 8.82 g + of trifluoracetic anhydride in 75 ml acetonitrile. The + mixture is allowed to stand at -20 C for about 1 1/2 (one and + one-half) hours. + + (During this time the suspended material dissolves and the + d-lysergic acid id converted to the mixed anhydride of + lysergic and trifluoracetic acids.) + + The mixed anhydride can be separated in the form of an oil by + evaporating the solvent in vacuo at a temperature below about + 0 Celsius. + + Everything must be kept anhydrous. + + +USING THE RED LIGHT: + + The solution of mixed anhydrides in acetonitrile from above is + added to 150 ml of acetonitrile containing 7.6 g of + diethylamine. + + The mixture is held in the dark at room temperature for about + 2 hours. + + The acetonitrile is evaporated in vacuo, leaving a residue of + LSD-25 plus impurities. + + The residue is dissolved in 150 ml of chloroform and 20 ml of + ice water. + + The chloroform layer is removed and the aqueous layer is + extracted with several portions of chloroform. The chloroform + portions are are combined and, in turn, washed with four 50 ml + portions of ice-cold water. + + The chloroform solution is then dried over anhydrous sodium + sulfate and evaporated in vacuo. + +NOTE: following the completion of this synthesis, follow the +procedures described for separation, purification, and +crystallization of LSD-25. If a higher yield is desired, follow +the procedure on isomerization after doing the separation, +purification, and crystallization. + + + + +#7: Synthesis of LSD + using lysergic acid + high-yielding and fast + + +PREPARATORY: see #4 + +NOTE: The chemicals and techniques described are potentially +dangerous. It is highly recommended that the physical and chemical +properties of the reagents used be studied by those persons +unfamiliar with them before the synthesis is attempted. + +NOTE: the following procedure gives good yield and is very fast, +with little iso-lysergic acid being produced. However, the +stoichiometry must be exact or yields will drop + + +USING WHITE LIGHT: + + Sulfur trioxide is produced in an anhydrous state by carefully + decomposing anhydrous ferric sulfate at approximately 480 + Celsius. Store under anhydrous conditions. + +USING WHITE LIGHT: + + A carefully-dried 22 liter RB flask fitted with an ice bath, + dropping funnel, and mechanical stirrer is charged with 10 to + 11 liters of dimethylformamide (freshly distilled under + reduced pressure). + + The condenser and dropping funnel are both protected against + atmospheric moisture. + + 2 lb. of sulfur trioxide (Sulfan B) are introduced dropwise, + very cautiously with stirring, during 4 to 5 hours. The + temperature is kept at 0-5 Celsius throughout the addition. + + After the addition is complete, the mixture is stirred for 1 + to 2 hours until some separated crystalline sulfur trioxide- + dimethylformamide complex has dissolved. + + The reagent is transferred to an air-tight automatic pipette + for convenient dispensing, and kept in the cold. Although the + reagent, which is colorless, may change to yellow and red, its + efficiency remains unimpaired for three to four months in cold + storage. + + An aliquot is dissolved in water and titrated with standard + NaOH to a phenolphthalein end point. + + +USING RED LIGHT: + + A solution of 7.15 g of d-lysergic acid monohydrate (25 mmol) + and 1.06 g of lithium hydroxide hydrate (25 mmol) in 200 L of + MeOH is prepared. + + The solvent is distilled on the steam bath under reduced + pressure. + + The residue of glass-like lithium lysergate is dissolved in + 400 ml of anhydrous dimethyl formamide. + + From this solution, about 200 ml of the dimethyl formamide is + distilled off at 15mm pressure through a 12-inch helices + packed column. + + The resulting anhydrous solution of lithium lysergate left + behind is cooled to 0 Celsius and, with stirring, treated + rapidly with 500 ml of SO3DMF solution (1.00 Molar). + + The mixture is stirred in the cold for 10 minutes and then + 9.14 g (125.0 mmol) of diethylamine is added. + + The stirring and cooling are continued for 10 minutes longer, + when 400 ml of water is added to decompose the reaction + complex. + + After mixing thoroughly, 200 ml of saturated aqueous saline + solution is added. The amide product is isolated by repeated + extraction with 500 ml portions of ethylene dichloride. + + The combined extract is dried and then concentrated to a syrup + under reduced pressure. Do not heat the syrup during + concentration. The LSD may crystallize out, but the crystals + and the mother liquor may be chromatographed according to the + instructions in the synthesis of LSD #4. + +X-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-X + Another file downloaded from: The NIRVANAnet(tm) Seven + + & the Temple of the Screaming Electron Taipan Enigma 510/935-5845 + Burn This Flag Zardoz 408/363-9766 + realitycheck Poindexter Fortran 510/527-1662 + Lies Unlimited Mick Freen 801/278-2699 + The New Dork Sublime Biffnix 415/864-DORK + The Shrine Rif Raf 206/794-6674 + Planet Mirth Simon Jester 510/786-6560 + + "Raw Data for Raw Nerves" +X-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-X diff --git a/textfiles.com/drugs/makecocaine.txt b/textfiles.com/drugs/makecocaine.txt new file mode 100644 index 00000000..80f2813b --- /dev/null +++ b/textfiles.com/drugs/makecocaine.txt @@ -0,0 +1,297 @@ + +********************************************************************** + + H O W T O M A K E C O C A I N E + +********************************************************************** + +BROUGHT TO YOU BY: CUBE 1994-05-04 + +********************************************************************** + +Welcome to the complete guide of how to make cocaine. If you do + +everything right you are going to be king of the world, either in your + +own world or in the real world. Please read the disclaimer at the end of + +this text. + +Now, let's get to action! + +The basic formula for cocaine starts by purchasing or making tropinine, + +converting the tropinone into 2-carbomethoxytropinone (also known as + +methyl-tropan-3-one-2-carboxylate), reducing this to ecgonine, + +and changing that to cocaine. + + Succindialdehyde. This can be purchased, too. 23.2 g of succinaldoxime + +powder in 410 ml of 1 N sulfuric acid and add dropwise with stirring at + +0* a solution of 27.6 g of sodium nitrite in 250 ml of water over + +3 hours. After the addition, stir and let the mixture rise to room temp + +for about 2 hours, taking care not to let outside air into the reaction. + +Stir in 5 g of Ba carbonate and filter. Extract the filtrate with ether + +and dry, evaporate in vacuo to get the succindialdehyde. This was t + +aken from JOC, 22, 1390 (1957). To make succinaldoxime, see JOC, 21, + +644 (1956). + + Complete Synthesis of Succindialdehyde. JACS, 68, 1608 (1946). In a 2 liter + +3 necked flask equipped with a stirrer, reflux condenser, and an addition + +funnel, is mixed 1 liter of ethanol, 67 g of freshly distilled pyrrole, and + +141 g of hydroxylamine hydrochloride. Heat to reflux until dissolved, add + +106 g of anhydrous sodium carbonate in small portions as fast as reaction + +will allow. Reflux for 24 hours and filter the mixture. Evaporate the + +filtrate to dryness under vacuo. Take up the residue in the minimum amount + +of boiling water, decolorize with carbon, filter and allow to recrystallize + +in refrigerator. Filter to get product and concentrate to get additional + +crop. Yield of succinaldoxime powder is a little over 40 g, mp is 171-172*. + + 5.8 g of the above powder is placed in a beaker of 250 ml capacity and + +54 ml of 10% sulfuric acid is added. Cool to 0* and add in small portions + +of 7 g of sodium nitrite (if you add the nitrite too fast, nitrogen dioxide + +fumes will evolve). After the dioxime is completely dissolved, allow the + +solution to warm to 20* and effervescence to go to completion. Neutralize + +the yellow solution to litmus by adding small portions of barium carbonate. + +Filter off the barium sulfate that precipitates. The filtrate is 90% pure + +succindialdehyde and is not purified further for the reaction to create + +tropinone. Do this procedure 3 more times to get the proper amount for the + +next step, or multiply the amounts given by four and proceed as described + +above. + + Take the total amount of succinaldehyde (obtained from 4 of the above + +syntheses combined) and without further treatment or purification (this had + +better be 15.5 g of succindialdehyde) put into an Erlenmeyer flask of + +4-5 liters capacity. Add 21.6 g of methylamine hydrochloride, 46.7 g of + +acetonedicarboxylic acid, and enough water to make a total volume of 2 + +liters. Adjust the pH to 8-10 by slowly adding a saturated solution of + +disodium phosphate. The condensate of this reaction (allow to set for + +about 6 days) is extracted with ether, the ethereal solution is dried + +over sodium sulphate and distilled, the product coming over at 113* at + +25 mm of pressure is collected. Upon cooling, 14 g of tropinone + +crystallizes in the pure state. + + 2-Carbomethoxytropinone. A mixture of 1.35 g of sodium methoxide + +(this is sodium in a minimum amount of methanol), 3.5 g of tropinone, + +4 ml of dimethylcarbonate and 10 ml of toluene is refluxed for 30 min. + +Cool to 0* and add 15 ml of water that contains 2.5 g of ammonium chloride. + +Extract the solution after shaking with with four 50 ml portions of + +chloroform, dry, evaporate the chloroform in vacuo. Dissolve the oil + +residue in 100 ml of ether, wash twice with a mixture of 6 ml of + +saturated potassium carbonate and three ml of 3 N KOH. Dry and evaporate + +in vacuo to recover the unreacted tropinone. Take up the oil in a solution + +of aqueous ammonium chloride and extract with chloroform, dry, and evaporate + +in vacuo to get an oil. The oil is dissolved in hot acetone, cool, and + +scratch inside of flask with glass rod to precipitate + +2-carbomethoxytropinone. Recrystallize 16 g of this product in 30 ml of hot + +methyl acetate and add 4 ml of cold water and 4 ml of acetone. Put in + +freezer for 2 1/2 to 3 hours. Filter and wash the precipitate with cold + +methyl acetate to get pure product. + + Methylecgonine. 0.4 mole of tropinone is suspended in 80 ml of ethanol + +in a Parr hydrogenation flask (or something that can take 100 psi and not + +react with the reaction, like stainless steel or glass). 10 g of Raney + +Nickle is added with good agitation (stirring or shaking) followed by + +2-3 ml of 20% NaOH solution. Seal vessel, introduce 50 psi of hydrogen + +atmosphere (after flushing vessel with hydrogen) and heat to 40-50*. + +After no more uptake of hydrogen (pressure gauge will hold steady after + +dropping to its lowest point) bleed off pressure and filter the nickle off, + +rinse out bottle with chloroform and use this rinse to rinse off the nickle + +while still on the filter paper. Make the filtrate basic with KOH after + +cooling to 10*. Extract with chloroform dry, and evaporate the chloroform + +in vacuo to get an oil. Mix the oil plus any precipitate with an equal + +volume of dry ether and filter. Add more dry ether to the filtrate until + +no more precipitate forms, filter and add to the rest of the precipetate. + +Recrystallize from isopropanol to get pure methylecgonine. Test for activity. + +If active, skip down to the step for cocaine. If not active, proceed as + +follows. Stir with activated carbon for 30 min, filter, evaporate in vacuo, + +dissolve the brown liquid in methanol, and neutralize with 10% HCl acid in + +dry ether. Evaporate the ether until the two layers disappear, and allow to + +stand for 2 hours at 0* to precipitate the title product. There are many + +ways to reduce 2-carbomethoxytropinone to methylecgonine. I chose to design + +a Raney Nickle reduction because it is cheap and not as suspicious as LAH + +and it is much easier than zinc or sodium amalgams. + + Cocaine. 4.15 g of methylecgonine and 5.7 g of benzoic anhydride in 150 ml + +of dry benzene are gently refluxed for 4 hours taking precaution against + +H20 (the 2 should be on a lower level) in the air (drying tube). Cool in an + +ice bath, acidify carefully with hydrochloric acid, dry, and evaporate in a + +vacuum to get a red oil which is treated with a little portion of isopropanol + +to precipitate cocaine. + + As you can see, this is quite a chore. The coca leaves give ecgonine, which + +as you can see, is only a jump away from cocaine. If you can get egconine, + +then dissolve 8 1/2 g of it in 100 ml of ethanol and pass (bubble) dry HC1 + +gas through this solution for 30 min. Let cool to room temp and let stand + +for another 1 1/2 hours. Gently reflux for 30 min and evaporate in vacuo. + +Basify the residue oil with NaOH and filter to get 8.4 g of methylecgonine, + +which is converted to cocaine as in the cocain step above. + + Below is given a somewhat easier method of producing tropinone by the + +general methods of Willstatter, who was instrumental in the first synthetic + +production of cocaine and several other alkaloids. After reviewing this + +method, I found it to be simpler than the above in many respects. + + Tropinone. 10 g of pyrrolidinediethyl diacetate are heated with 10 g of + +cymene and 2 g of sodium powder, the reaction taking place at about 160*. + +During the reaction (which is complete in about 10 min) the temp should not + +exceed 172*. The resulting reaction product in dissolved in water, then + +saturated with potassium carbonate, and the oil, which separates, is boiled + +with dilute sulfuric acid. 2.9 g of tropinone picrate forms and is filtered. + +Here are two more formulas devised by Willstatter that produce tropinone + +from tropine. Take note of the yield differences. + + Tropinone. To a solution of 25 g tropine, dissolved in 10 times its weight + +of 20% sulfuric acid are added 25 g of a 4% solution of potassiumpermanganate + +in 2 or 3 g portions over 45 min while keeping the temp at 10-12*. The + +addition of permanganate will cause heat (keep the temp 10-12*) and + +precipitation of manganese dioxide. The reaction mixture is complete in + +1 hour. A large excess of NaOH is added and the reaction is steam distilled + +until 1 liter of distillate has been collected. The tropinone is + +isolated as the dibenzal compound by mixing the distillate with 40 g of + +benzaldehyde in 500 cc of alcohol and 40 of 10% sodium hydroxide solution. + +Let stand several days to get dibenzaltropinone as yellow needles. + +Yield: 15.5 g, 28%. Recrystallize from ethanol to purify. + + Tropinone. A solution of 12 g of chromic acid in the same amount of + +water (12 g) and 60 g of glacial acetic acid is added dropwise with stirring + +over a period of 4 hours to a solution of 25 g of tropine in 500 cc of + +glacial acetic acid that has been warmed to 60-70* and is maintained at this + +temp during the addition. Heat the mixture for a short time on a steam bath + +until all the chromic acid has disappeared, cool and make strongly alkaline + +with NaOH. Extract with six 500 cc portions of ether and evaporate the ether + +in vacuo to get an oil that crystallizes readily. Purify by convering to the + +picrate or fractionally distill, collecting the fraction at 224-225* at + +714 mm vacuo. + + The tropinones can be used in the above formula (or in a formula that you + +have found elsewhere) to be converted to cocaine. Remember to recrystallize + +the 2-carbomethoxytropinone before converting to methylecgonine. + +---------------------------------------------------------------------- + +This text is spread for informational purpose only. I am not responsible + +if someone is injured while using this information. After all, information + +wants to be free. + +---------------------------------------------------------------------- + diff --git a/textfiles.com/drugs/makelsd.fun b/textfiles.com/drugs/makelsd.fun new file mode 100644 index 00000000..a57e66d3 --- /dev/null +++ b/textfiles.com/drugs/makelsd.fun @@ -0,0 +1,73 @@ +******NOTICE: This File is Pure Bullshit. If you make this stuff, and take +it, you will probably end up killing yourself.****** + +MAKING LSD +------ --- + + + Common LSD, being of the strangest drugs, available to people on the +black market, is not too hard to make in your average run-of-the-mill +kitchen. LSD (Lysergic acid Diethylamide) is a complex organic mixure that +gives some people (most) a trip to the moon or other nearby celestial +body. + + +ITEMS NEEDED: +----- ------ + +1-About 200-250 grams of MORNING GLORY SEEDS or BAY HAWAIIAN WOOD ROSE +SEEDS. The Morning Glory seeds can be obtained at most plant nurseries. + +2-200 cc. of petroleum ether + +3-Small piece of window screen or a strainer + +4-A couple of large glasses + +5-cookie tray (an old one, never to be used again) + +6-260 cc. of wood alcohol (call your local drug store). + +7-Capsule containers (jel) + +========================================================================= + +Let's get started: + +1. Grind up about 170 grams of Morning Glory Seeds. + +2. In 145 cc. of petroleum ether, soak the seeds for two or three days. + +3. With screen, filter the liquid thru it and save the seed mush and +allow it to dry completely. + +4. Let the mush soak in 130 cc. of +wood alcohol. + +5. Filter solution again only. Save the liquid in a large glass jar. + +6. Soak the seed mush again in 130 cc. of wood alcohol for two more days. + +7. Filter out the mush and keep the liquid. Now, get the liquid that was +saved in step 5. + +8. Now, pour both liquids in a cookie tray and let it dry. + +9. When all the liquid has dried, a yellowish gummy looking substance will +appear on the cookie sheet. + +10. Take the yellow gum and put this into capsules. + +========================================================================= + +You can get the capsules just by buying something like DEXITRIM or some +other pill. Even CONTACT comes in jel capsules. Just empty them out and +put the yellow gum in the capsules. Allow the capsules to sit over night +for best results. + + +34 Grams of morning glory=1 trip to da moon +18 Grams of hawaiian wood=Another trip to da moon + + + diff --git a/textfiles.com/drugs/makelsd.hac b/textfiles.com/drugs/makelsd.hac new file mode 100644 index 00000000..2377b847 --- /dev/null +++ b/textfiles.com/drugs/makelsd.hac @@ -0,0 +1,42 @@ + ==================== + = MAKING LSD = + ==================== +LSD, being of the strangest drugs, is available to people on the black +market, is not too hard to make in your average run-of-the-mill kitchen. +LSD (LySergic acid Diethylamide) is a complex organic mixture that gives +some people (most) +================================ +Making LSD: ITEMS NEEDED: + 1-About 200-250 grams of MORNIGLOR SEEDS or BAY HAWAIIAN OOD ROSE SEEDS. + The Morning Glory Seeds can be obtained at most plant nurseries. + 2-200 cc. of petroleum ether + 3-Small piece of window screen or a strainer. + 4-A couple of large glasses. + 5-One cookie try (old on to never be used again). + 6-260 cc. of wood alcohol (call your local drug store). + 7-Capsule containers (jel) +================================ +Lets get started: + 1. Grind up about 170 grams of Morning Glory Seeds. + 2. In 145 cc of petroleum ether, soak the seeds for two or three days. + 3. With screen, filter the liquid thru it and save the seed mush and allow + it to dry completely. + 4. Let the mush soak in 130 cc. of wood alcohol. + 5. Filter solution again only. Save the liquid in a large glass jar. + 6. Soak the seed mush again in 130 cc. of wood alcohol for two more days. + 7. Filter out the mush and keep the liquid. Now, get the liquid that was + saved in step 5. + 8. Now, pour both liquids in a cookie tray and let it dry. + 9. When all the liquid has dried, a yellowish gummy looking substance will + appear on the cookie sheet. + 10. Take the yellow gum and put these in to capsules. +================================ +You can get the capsules just by buying something like DEXITREM or some other +pill. Even CONTACT comes in jel capsules. Just empty them out and +put the yellow gum in the capsules. Allow the capsules to sit over night +for best results. + +1 Trip: + 34 Grams of morning glory + 18 Grams of hawaiian wood +================================ \ No newline at end of file diff --git a/textfiles.com/drugs/makex.doc b/textfiles.com/drugs/makex.doc new file mode 100644 index 00000000..0faffb5d --- /dev/null +++ b/textfiles.com/drugs/makex.doc @@ -0,0 +1,68 @@ +Manufacture of "Ecstacy" +from Chemical Abstracts 52, 11965 (1958) + +For Informational Purposes Only. The authors & distributors +do not advocate the use of illegal drugs and assume no liability +for the use or misuse of this information . The procedures described +are dangerous and should not be attempted by persons inexperienced +in Organic Laboratory techniques. + +This formula is exemplified for MDA (3,4-Methylenedioxy- +phenylisopropylamine); substituting N-methyl formamide +results in MDMA or N-methyl MDA (Ecstacy). + +To a cooled mixture of 34 g 30% H2O2 and 150 g formic acid, add +dropwise a solution of 32.4 g (0.2M) isosafrole in 120 ml acetone, +(keep temperature below 30 degrees) Let stand twelve hours and +evacuate in vacuum. Add 60 ml methanol and 369 g 15% sulfuric +acid to the residue and heat on a water bath three hours. Cool, +extract with ether or benzene and evaporate in vacuum the extract +to give 20 g 3,4,-methylenedioxybenzylmethyl ketone. + +Add 23 g of above ketone to 65 g formamide and heat at 190 degrees +for five hours. Cool, add 100 ml H2o2, extract with benzene and +evaporate in vacuum the extract. Add 8 ml methanol and 57 ml 15% +HCL to residue, heat on water bath two hours and evaporate in +vacuum (or basify with KOH and extract the oil with benzene and dry, +evaporate in vacuum) to get 11.7 g MDA. + +The above occurs as a yellowish brown oil; this is active orally, +but somewhat inconvenient; to convert to powder (salt) form, reflux +in Hydrochloric acid and evaporate. + +Safrole, an allyl benzene, occurs naturally in oil of sassafras, +about 70%. Can be extracted with simple distillation. It is con- +verted to isosafrole (a propenyl benzene) by adding equal weight +of KOH flakes and absolute ethanol and heating on steam bath or +refluxing for 24 hours; dried and evaporated in vacuum or added +with two time its volume in water and extracted with ether or +methylene chloride and dried, evaporated in vacuum. Hexane is used +for recrystalization. + +Formamide and N-methyl formamide are closely watched by the DEA. +Many people have been busted by small suppliers where it was easy +to get; those are "sting" operations that tail the buyer home. + +Show this to one of your Chem major pals. + + + + + Another file downloaded from: + + ! + -$- & the Temple of the Screaming Electron + ! * Walnut Creek, CA + + /^\ | + ! | |/\/^\ _^_ 2400/1200/300 baud (415) 935-5845 + /^\ / @ | \/_-_\ Jeff Hunter, Sysop + |@ \_| @ @|- - -| \ + | | | /^\ | _ | - - - - - - - - - * + |___/_\___|_|_|_(_)_| Aaaaaeeeeeeeeeeeeeeeeee! / + + Specializing in conversations, E-Mail, obscure information, + entertainment, the arts, politics, futurism, thoughtful discussion, + insane speculation, and wild rumours. An ALL-TEXT BBS. + + "Raw Data for Raw Nerves." + diff --git a/textfiles.com/drugs/makex.txt b/textfiles.com/drugs/makex.txt new file mode 100644 index 00000000..1ce057f9 --- /dev/null +++ b/textfiles.com/drugs/makex.txt @@ -0,0 +1,65 @@ +Manufacture of "Ecstacy" +from Chemical Abstracts 52, 11965 (1958) + +For Informational Purposes Only. The authors & distributors +do not advocate the use of illegal drugs and assume no liability +for the use or misuse of this information . The procedures described +are dangerous and should not be attempted by persons inexperienced +in Organic Laboratory techniques. + +This formula is exemplified for MDA (3,4-Methylenedioxy- +phenylisopropylamine); substituting N-methyl formamide +results in MDMA or N-methyl MDA (Ecstacy). + +To a cooled mixture of 34 g 30% H2O2 and 150 g formic acid, add +dropwise a solution of 32.4 g (0.2M) isosafrole in 120 ml acetone, +(keep temperature below 30 degrees) Let stand twelve hours and +evacuate in vacuum. Add 60 ml methanol and 369 g 15% sulfuric +acid to the residue and heat on a water bath three hours. Cool, +extract with ether or benzene and evaporate in vacuum the extract +to give 20 g 3,4,-methylenedioxybenzylmethyl ketone. + +Add 23 g of above ketone to 65 g formamide and heat at 190 degrees +for five hours. Cool, add 100 ml H2o2, extract with benzene and +evaporate in vacuum the extract. Add 8 ml methanol and 57 ml 15% +HCL to residue, heat on water bath two hours and evaporate in +vacuum (or basify with KOH and extract the oil with benzene and dry, +evaporate in vacuum) to get 11.7 g MDA. + +The above occurs as a yellowish brown oil; this is active orally, +but somewhat inconvenient; to convert to powder (salt) form, reflux +in Hydrochloric acid and evaporate. + +Safrole, an allyl benzene, occurs naturally in oil of sassafras, +about 70%. Can be extracted with simple distillation. It is con- +verted to isosafrole (a propenyl benzene) by adding equal weight +of KOH flakes and absolute ethanol and heating on steam bath or +refluxing for 24 hours; dried and evaporated in vacuum or added +with two time its volume in water and extracted with ether or +methylene chloride and dried, evaporated in vacuum. Hexane is used +for recrystalization. + +Formamide and N-methyl formamide are closely watched by the DEA. +Many people have been busted by small suppliers where it was easy +to get; those are "sting" operations that tail the buyer home. + +Show this to one of your Chem major pals. + + + + + + +X-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-X + Another file downloaded from: The NIRVANAnet(tm) Seven + + & the Temple of the Screaming Electron Taipan Enigma 510/935-5845 + Burn This Flag Zardoz 408/363-9766 + realitycheck Poindexter Fortran 510/527-1662 + Lies Unlimited Mick Freen 801/278-2699 + The New Dork Sublime Biffnix 415/864-DORK + The Shrine Rif Raf 206/794-6674 + Planet Mirth Simon Jester 510/786-6560 + + "Raw Data for Raw Nerves" +X-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-X diff --git a/textfiles.com/drugs/mandrake.txt b/textfiles.com/drugs/mandrake.txt new file mode 100644 index 00000000..69266d08 --- /dev/null +++ b/textfiles.com/drugs/mandrake.txt @@ -0,0 +1,45 @@ +Newsgroups: alt.drugs + + recently i had a day off from work and decided to spend it +experimenting with mandrake root. Mandrake contains scopalamine, +which is (along with atropine) also found in thorn apple/belladonna. +both were commonly used in 'witches potions' to induce out of body +experiences, so my plan was to try to leave my body. these drugs +are known to cause some unpleasant (but, i thought, hallucinogenic) +effects. + + well, because a housemate had tried mandrake last year at a +certain dosage with no effects noticable enough to count, i decided +to make a much stronger tea with it. it is mind-bogglingly bitter, +and because i mixed moleasses with it for sweetness, the tastes are +associated for me and i can't stand even the smell of molasses anymore. +i made about 1.5-2 pts of tea with around 6 tablespoons of mandrake. +drank a bunch, nothing. drank another glass. felt some vague feelings, +thought 'maybe it's coming on' and lay down to focus on it. it faded +in around ten minutes +so i drank more. i played tag like this with vague effects for a while, +taking huge gulps in an attempt to get strong effects from it. eventually +i quit, and went out for dinner. i felt no effects. + + as soon as i ate a medium-sized meal, my stomach began to hurt. +i lay in bed for a while, feeling like i had indigestion. well, that feeling +turned into the most horrific drug experience i can even imagine having. +it did not involve any alteration of consciousness except that caused by the +waves of cold chills, the protracted vomiting fits which dredged up stuff +i'd eaten 8 or more hours earlier, and the diaherria which shortly consisted +solely of yellowish water. for close to 10 hours all i could do was lay +shivering under tons o' quilts, crawl to the bathroom to puke up clots of +fairly-well-digested food and quarts of water i'd been drinking to keep +hydrated, and shit water. i almost had someone take me to the hospital, +even knowing how barbaric they are there about drugs (they tried to help +a friend who was freaking out on mushrooms and made the mistake of going +there by interrogating her for almost an hour about where she got the shrooms) + eventually my girlfriend found a reference to mandrake which said +it could be used as an emetic, a very powerful emetic, and not to usde it +since other less dangerous herbs give the same effects. they said, if you +were driven for some reason to use it, to make a tea approx. 1/6 the +strength of the one i'd made, and sip a tablespoon an hour for four hours. +holy shit i drank about two pints o the shit! + + moral of the story: stick to legit, illegal drugs. + diff --git a/textfiles.com/drugs/maobad.txt b/textfiles.com/drugs/maobad.txt new file mode 100644 index 00000000..40bb4ed6 --- /dev/null +++ b/textfiles.com/drugs/maobad.txt @@ -0,0 +1,60 @@ +From Legal Highs by The Twentieth Century Alchemist, published sometime in the +early 1970's: + + DANGEROUS COMBINATIONS + + Unless one is very experienced in pharmacology, it is unwise to +experiment with combinations of drugs. Even when using a single drug, thought +should be given to all substances, both food and drug, which have been taken +recently. Most primitive people fast or at least abstain from certain +substances for several days prior to taking a sacrament. Substances most +universally avoides are alcohol, coffee, meat, fat and salt. Some drugs +potentiate others. For example, atropine will increase the potency of +mescaline, harmine, cannabis and the opiates. Many of the substances +discussed in this book are MAO inhibitors. MAO (monoamine oxidase) is and +enzyme produced in the body which breaks down certain amines and renders them +harmless and ineffective. An MAO inhibitor interferes with the protective +enzyme and leaves the body vulnerable to these amines. A common substance +such as tyramine, which is usually metabolized with little or no +pharmacological effect, may become dangerous in the presence of an MAO +innhibitor and cause headache, stiff neck, cardiovascular difficulties, and +even death. MAO inhibitors may intensify and prolong the effects of other +drugs (CNS depressants, narcotic analgesics, anticholinergics, dibenzazepine +antidepressants, etc.) by interfering with their metabolism. In the presence +of an MAO inhibitor many substances which are ordinarily non-active because of +their swift metabolism may become potent psychoactive drugs. This phenomenon +may creat a new series of mind alterants. However, because of the complex and +precarious variables involved, it is risky and foolish for anyone to +experiment with these possibilities on the non-professional level. + The most commonly used MAO inhibitors include hydrazines such as +iproniazid, Marsilid, Marplan, Niamid, Nardil, Catron; also non-hydrazines +such as propargylamines, cyclopropylamines, aminopyrazine derivatives, +indolealkylamines, and carbolines. MAO inhibiting materials discussed in this +book include yohimbine, various tryptamines, especially 5-MeO-DMT and the +alpha-methyltryptamines, and the various harmala alkaloids. The latter are +especially potent inhibitors, but, like yohimbine and the tryptamines, are +short-lasting in action (30 minutes to several hours). Some of the commercial +MAO inhibitors listed above are effective for several days to several weeks. + Among the material which may be dangerous in combination with MAO +inhibitors are sedatives, tranquilizers, antihistamines, narcotics and +alcohol--any of which can cause hypotensive crises (severe blood pressure +drop); and amphetamines (even diet pills), mascaline, asarone, nutmeg (active +doses), macromerine, ephedrine, oils of dill, parsley or wild fennel, beer, +wine, cocoa, aged cheeses and other tyrosine-containing foods (tyrosine is +converted to tyramine by bacteria in the bowel)--any of which can cause +hypertensive crises (severe blood pressure rise). + + +X-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-X + Another file downloaded from: The NIRVANAnet(tm) Seven + + & the Temple of the Screaming Electron Taipan Enigma 510/935-5845 + Burn This Flag Zardoz 408/363-9766 + realitycheck Poindexter Fortran 510/527-1662 + Lies Unlimited Mick Freen 801/278-2699 + The New Dork Sublime Biffnix 415/864-DORK + The Shrine Rif Raf 206/794-6674 + Planet Mirth Simon Jester 510/786-6560 + + "Raw Data for Raw Nerves" +X-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-X diff --git a/textfiles.com/drugs/maryjane.txt b/textfiles.com/drugs/maryjane.txt new file mode 100644 index 00000000..d22a798a --- /dev/null +++ b/textfiles.com/drugs/maryjane.txt @@ -0,0 +1,277 @@ +From: verdant@titan.ucs.umass.edu (Sol Lightman) +Newsgroups: alt.drugs +Subject: Mary Jane, Tobacco, & cigarettes (was FUCK NICOTINE) +Summary: Info on comparison of MJ and tobacco; cigarette additives +Message-ID: <1jcc8kINNn7u@titan.ucs.umass.edu> +Date: 17 Jan 93 19:32:36 GMT +Organization: University of Massachusetts, Amherst +Lines: 277 + +The following is the text of a pamphlet I wrote for an organization +at UMASS amherst + +It is an attempt to point out some of the absurdities in the marijuana- +is-bad-for-you-like-cigarettes bullshit, as well as take a few cheap +(but well aimed) shots at the tobacco industry. +It is written from a pro-marijuana-relegalization perspective, +and if you want a copy, mail us a Self Addressed Stamped Envelope. +(we're poor.) + +ATTN! to those who were wondering earlier about cigarrette additives. +data on government lists of additives enclosed. + +If any mistakes are present, do point out. + + +(see "fuck nicoteen") + +An address and some sources are at the end. + + +So, you thought it was the tar that caused cancer... + + + Think again. Cigarette companies will have you believing +anything just as long as you continue to buy their products. The +fact is, although insoluble tars are a contributing factor to the +lung cancer danger present in today's cigarettes, the real danger +is radioactivity. According to U.S. Surgeon General C. Everette +Koop (on national television, 1990) radioactivity, not tar, +accounts for at least 90% of all smoking related lung cancer. + Tobacco crops grown in the United States are fertilized by law +with phosphates rich in radium 226. In addition, many soils have +a natural radium 226 content. Radium 226 breaks down into two long +lived 'daughter' elements -- lead 210 and polonium 210. These +radioactive particles become airborne, and attach themselves to the +fine hairs on tobacco leaves. + Studies have shown that lead 210 and polonium 210 deposits +accumulate in the bodies of people exposed to cigarette smoke. +Data collected in the late 1970's shows that smokers have three +times as much of these elements in their lower lungs as non +smokers. Smokers also show a greater accumulation of lead 210 and +polonium 210 in their skeletons,though no studies have been +conducted to link these deposits with bone cancer. Polonium 210 is +the only component of cigarette smoke which has produced tumors by +itself in inhalation experiments with animals. + When a smoker inhales tobacco smoke, the lungs react by +forming irritated areas in the bronchi. All smoke produces this +effect. However, although these irritated spots are referred to as +'pre-cancerous' lesions, they are a perfectly natural defense +system and usually go away with no adverse effects. Insoluble tars +in tobacco smoke can slow this healing process by adhering to +lesions and causing additional irritation. In addition, tobacco +smoke causes the bronchi to constrict for long periods of time, +which obstructs the lung's ability to clear itself of these +residues. + Polonium 210 and lead 210 in tobacco smoke show a tendency to +accumulate at lesions in specific spots, called bifurcations, in +the bronchi. When smoking is continued for an extended period of +time, deposits of radioactivity turn into radioactive 'hot spots' +and remain at bifurcations for years. Polonium 210 emits highly +localized alpha radiation which has been shown to cause cancer. +Since polonium 210 has a half life of 21.5 years, it can put an +ex-smoker at risk for years after he or she quits. Experiments +measuring the level of polonium 210 in victims of lung cancer found +that the level of 'hot spot' activity was virtually the same in +smokers and ex-smokers even though the ex-smokers had quit five +years prior to death. + Over half of the radioactive materials emitted by a burning +cigarette are released into the air, where they can be inhaled by +non-smokers. In addition to lead 210 and polonium 210 it has been +proven that tobacco smoke can cause airborne radioactive particles +to collect in the lungs of both smokers and non-smokers exposed to +second hand smoke. Original studies conducted on uranium miners +which showed an increased risk of lung cancer due to exposure to +radon in smokers have been re-run to evaluate the radioactive lung +cancer risk from indoor air radon. It turns out that tobacco smoke +works as a kind of 'magnet' for airborne radioactive particles, +causing them to deposit in your lungs instead of on furniture. +(Smoking indoors increases lung cancer risks greatly.) + It has been estimated that the total accumulated alpha +radiation exposure of a pack-a-day indoor smoker is 38 to 97 rad by +age 60. (Two packs a day yields up to 143 rad, and non-smokers +receive no more than 17 rad.) An exposure of 1 rad per year yields +a 1% risk of lung cancer (at the lowest estimate.) + Don't smoke. Or if you do, smoke lightly, outdoors, and +engage frequently in activities which will clear your lungs. +Imported India tobacco has less than half the radiation content of +that grown in the U.S. + Kicking the nicotine habit is not easy, and nobody has the +right to expect it of you. Often physical addictions are +reinforced by emotional and psychological needs. Filling or coming +to terms with those needs can give you the inspiration and added +freedom to succeed. + Most of all, inform yourself, even if the information is +disturbing. You are a lot less likely to be taken in by tobacco +advertising once you know the facts. + + + Nicotine, the active ingredient in tobacco smoke, has long +been known to be highly addictive. In fact, doctors and +pharmacologists are not in consensus as to which is more addictive +-- nicotine, or heroin. Physical addiction occurs when a chemical +becomes essential for the body or metabolism to function. In other +words, a substance is said to be physically addictive if extended +use results in a build up of tolerance in the body to the extent +that discontinuing use of the substance results in negative side +effects. Called "withdrawal symptoms," these consequences can +include anxiety, stress, trauma, depression and physical conditions +such as shakes or nausea. It is to avoid these consequences that +an addict will keep using his or her substance. + In addition to being addictive, nicotine is also a toxin (i.e. +lethal if ingested in sufficient quantities.) Nicotine has been +shown to have a negative effect on the heart and circulatory +systems, causing a constriction in veins and arteries which may +lead to a stroke or heart attack. In fact, nicotine is so +poisonous that smokers who ignore their doctor's advice and +continue to smoke while using dermal nicotine patches have managed +to overdose and die of heart seizure. + + Many people think smoking marijuana is just as harmful as +smoking tobacco, but this is not true. Those who hold that +marijuana is equivalent to tobacco are misinformed. Due to the +efforts of various federal agencies to discourage use of +marijuana in the 1970's the government, in a fit of "reefer +madness," conducted several biased studies designed to return +results that would equate marijuana smoking with tobacco smoking, +or worse. + For example the Berkeley carcinogenic tar studies of the +late 1970's concluded that "marijuana is one-and-a-half times as +carcinogenic as tobacco." This finding was based solely on the +tar content of cannabis leaves compared to that of tobacco, and +did not take radioactivity into consideration. (Cannabis tars do +not contain radioactive materials.) In addition, it was not +considered that: + 1) Most marijuana smokers smoke the bud, not the leaf, of +the plant. The bud contains only 33% as much tar as tobacco. + 2) Marijuana smokers do not smoke anywhere near as much as +tobacco smokers, due to the psychoactive effects of cannabis. + 3) Not one case of lung cancer has ever been successfully +linked to marijuana use. + 4) Cannabis, unlike tobacco, does not cause any narrowing of +the small air passageways in the lungs. + In fact, marijuana has been shown to be an expectorant and +actually dilates the air channels it comes in contact with. This +is why many asthma sufferers look to marijuana to provide relief. +Doctors have postulated that marijuana may, in this respect, be +more effective than all of the prescription drugs on the market. + Studies even show that due to marijuana's ability to clear +the lungs of smog, pollutants, and cigarette smoke, it may +actually reduce your risk of emphysema, bronchitis, and lung +cancer. Smokers of cannabis have been shown to outlive non- +smokers in some areas by up to two years. Medium to heavy +tobacco smokers will live seven to ten years longer if they also +smoke marijuana. + Cannabis is also radically different from tobacco in that it +does not contain nicotine and is not addictive. The psychoactive +ingredient in marijuana, THC, has been accused of causing brain +and genetic damage, but these studies have all been disproven. +In fact, the DEA's own Administrative Law Judge Francis Young has +declared that "marijuana in its natural form is far safer than +many foods we commonly consume." + + The disturbing thing about all of this information is that +the majority of Americans are as yet unaware of the radioactive +risk in cigarettes. In fact, many professionals: doctors, +scientists and health administrators, either have never heard of +polonium 210 or consider it to be just another scare story. + Why is this information so hard to come by? When the +studies were first released in the late 70's, many magazines were +unable to print articles because their main advertisers, +cigarette companies, threatened to pull support if they published +the facts. Although network news did pick up the story, +virtually nothing came out in print. Those who heard were hard +pressed to produce collaborating evidence, and were eventually +convinced it was nothing to worry about. + The power of the cigarette industry to suppress information +goes far beyond magazines, however. A well financed tobacco +lobby has been very active in the United States Congress for +decades procuring subsidies and fighting laws and proposed +research which could hurt the American tobacco industry. Tobacco +interests practically own Senate and House seats, as many +campaign contributions come from cigarette profits. Tobacco pay- +offs also go to fund organizations such as the Partnership For A +Drug Free America, which adopt a harsh anti-drug agenda yet seem +to omit alcohol and tobacco (claiming they are harmless.) + As an example, a 1984 law which was intended to require +tobacco companies to release to the public a list of additives +used in the manufacture of cigarettes was watered down to the +extent that the list is now released only to the Department of +Health and Human Services on the condition that it not be shown +to anyone else. Companies have been known in the past to add +chemicals to cigarettes for flavor, and, many assert, for their +addictive properties. In Britain such chemicals have included +acetone and turpentine, as well as an assortment of known +carcinogens. + Tobacco companies argue that revealing their 'secret +ingredients' would hurt their competitiveness. In fact, when +Canada passed legislation forcing additive lists to be released, +one large company reformulated its recipe for its Canadian +distribution; another took its product out of Canada entirely. + Tobacco companies do not have the right to poison the +public. Don't trust them. Get the information you need to make +your own decisions, and restore government to the people. + + Another destructive aspect of the Drug War is the +unreasonable measures taken as a result of "reefer madness." +Because of the long standing anti-pot-smoking paranoia begun in +the 1930's, many law enforcement agencies have taken it upon +themselves to censor and limit the marijuana culture through +whatever channels they can find. This includes the banning of +various forms of drug "paraphernalia" (pipes, clips, rolling +papers, etc.) + Water pipes, or "bongs," are quite often the target of such +efforts. Claiming that water pipes are constructed to allow +marijuana smokers to inhale "dangerous" marijuana smoke deeper +into their lungs, many states and towns have passed laws +controlling the sale, manufacture, and possession of these items +for "health" reasons. + The sad fact is, water pipes have been shown to be extremely +effective in removing harmful materials from smoke before it +reaches the lungs. They also cool the smoke and prevent injury +and irritation to lung passages. In effect, laws against water +pipes hurt all smokers, cannabis and tobacco, by preventing the +development of safer forms of consumption. + +Produced as a public service by the University of Massachusetts +at Amherst Cannabis Reform Coalition +Research and written by Brian S. Julin +Corrections, comments, inquiries should be addressed to: +UMASS CANNABIS +S.A.O. Box #2 +Student Union +UMASS Amherst, MA +01003 + + +Sources: + (radioactivity) +E.A. Martel, "Alpha Radiation Dose at Bronchial Bifurcations +>From Indoor Exposure to Radon Progeny", Proceeds of the National +Academy of Science, Vol. 80, pp. 1285-1289, March 1983. +Naoimi H. Harley, Beverly S. Cohen, and T.C. Tso, "Polonium 210: +A Questionable Risk Factor in Smoking Related Carcingenisis." +"Radiactivity: the New-Found Danger in Cigarettes," Reader's +Digest, March 1986. +"Would You Still Rather Fight Than Switch?," Whole Life Times, +Mid-April/May 1985. + (secret ingredients) +"What Goes Up In Smoke?," Nation, December 23, 1991. + +---- + +I also heard that cigarette companies have as many as 400 chemicals +to add to cigarettes, including placing a small, almost indetectable +quantity of sugar or chocolate on the lip of the cigarette to give +you a dex rush (just a small one) as a way of saying, "hello, baby, +let me get that monkey of your back." The goal of this is to increase +the addictiveness of said death stick. +The companies don't seem to care about what it does to their customers, +(you can always grow more suckers, birth is cheap, just ban contraceptives.) + +Anyway, Indian grown tobacco has the lowest radioactive content, +buy it wrapped, untreated (except for curing) at tobacco specialty shops, +they wrap the cigarettes in tobacco leaf (no paper.) + + +Bri diff --git a/textfiles.com/drugs/maryjanecm.drg b/textfiles.com/drugs/maryjanecm.drg new file mode 100644 index 00000000..bad73a71 --- /dev/null +++ b/textfiles.com/drugs/maryjanecm.drg @@ -0,0 +1,462 @@ + + ================================================= + The Official Criminal Minded Mary Jane Guide! + ================================================= + +Disclaimer: Pot is illegal and I don't give a fuck. + +Congratulations! You are now the proud owner of your very own personal copy +of the -OFFICIAL- Criminal Minded Mary Jane Guide!!! (Please do NOT be +fooled by cheap imitations) + +First off I want you to observe the lovely artwork included in this guide: + + * + *** + * *** * + ** ***** ** + *** ***** *** + **** ***** **** + ** ****** ***** ****** ** + ****** ****** *** ****** ****** + ****** **** *** **** ******* + ******* ** * ** ******* + ********************* + ********* + **** * **** + ** * ** + * + * + +Wasn't that beautiful? Such magnificent color! Such outstanding clarity! + +Anyway: + +In this guide: + +============================================================================= + +Part 1: Starting The Growth Process - + +Part 2: Taking care of the newborns - How to insure the survival of your + newly sprouted plants. + +Part 3: Maintaining the plants once they start to get bigger. + +Part 4: Preparation of the plant for 'consumption' + +Part 5: Security and safety measures. + +Part 6: Criminal Minded's mini guide to enjoying your plants! + +Part 7: Final Notes. + +============================================================================= + +Part 1: Ok, this first step is, of course, the most important step in + assuring the successful start of a nice healthy plant or plants. + The trick to it is to "germinate" the seeds. This is very easily + done. All you have to do is take two paper napkins and place the + seeds in between them. Once that is done, put them in a warm spot + and keep the napkins moist. Keep them like this for a week or so. + You will know when they are ready because the seed will split open + and a little white thing will protrude from the seed. + + Note: I recommend germinating at least 10 seeds. This makes your + chances of results much better. + +BONUS Crimmy Tip!!! --> Use a miracle gro/water mixture to germinate the seeds + with. Miracle gro (the powdered kind) comes with a + little 'dual scoop' inside the box. Use the smaller + scoop and mix that much miracle gro with a half gallon + of water. If you use tap water I suggest that you boil + it first to remove as much germs and other nasties from + the water to prevent disease in your plants. Anyway, the + miracle gro/water mixture used to germinate the seeds + gives, in my opinion, the seeds a head start. They are + spoiled from day one so keep in mind you must always + spoil them. + +Important Note: DO NOT put too much miracle gro powder in the water because + it can burn through the leaves and the roots. Read the back + of the box for specific instructions. + +BONUS Crimmy Tip!!! --> Before the week is up take ten small pots and fill + them with ORGANIC potting soil to about here: + + ------------------ + Pot ---> \ / + | | + Soil line --> |______________| + | | + | | + ---------------- + + [Please note, once again, the spectacular graphics above] + +Once you have filled them with soil take the required (see chart below) number +of Jobes Plant Spikes for each pot and place them around the sides of the pot +spacing them equal distances apart. + +Chart from back of Jobe's plant spikes package: + +----------------------------------------------------------- +Pot Diameter (inches): 4 6 8 10 12 +----------------------------------------------------------- +Use This Many Spikes: 2 3 4 5 6 +----------------------------------------------------------- + +Then take your miracle gro/water solution and wet the soil so that it is +moist, not saturated. You want to keep the soil moist for the entire week +while your seeds are germinating. After the week is up you are now ready. + +Take your finger and push it halfway down into the soil in the middle of the +pot. The hole is where the seed will go (duh). Now remove your seeds from the +paper napkins and carefully drop one in each of the pots (only one seed per +pot). Now just gently fill the hole with dirt and that's it. You should see +some sprouts within 1 to 5 days. If you do not see anything withing 7-10 days, +try again. + +Now onto Part 2: + +Once your seeds have sprouted taking care of them is basically elementary. + +1. If there is any dirt or pebbles wedged in between the leaves of the plant + gently remove them. +2. Keep them warm. +3. Keep the soil moist (with the miracle gro mixture of course). +4. Keep any large pebbles or anything else that might obstruct their growth + away from them. (Sometimes you will find rocks/pebbles/twigs in with + potting soil). +5. Spray them very gently with the miracle gro mixture. Do not spray them + full blast with your spray bottle. + +and most important: + +As the newborn plant gets bigger gently add more soil around the base of the +plant so that the top of the soil is just beneath the top of the seedling. +This provides more support for it as it grows (they tend to fall over) and +promotes root growth. Once they look strong enough to support themselves you +can stop adding more soil. I'd say this time would be when they are a few +inches tall. + +Note: When your plant reaches around 10-12 inches tall I suggest transplanting + it into a bigger pot. The bigger the better because you will have to + transplant it less often, reducing the possibility of it going into + shock and dying. To transplant it, gently edge a butter knife around + the edge of the pot to loosen the soil and then tip the pot upside down + and gently shake it. It should come out as a whole. Then just dig a + hole in the soil of the new pot and insert your plant and soil plug. + Then cover it with new soil and water a little. + +Part 3: Maintaining the plants once they get bigger. + +1. As your plants get bigger you will notice leaves closer to the middle of + the plant that are starting to turn brown on the tips and curl up. After a + while just gently pull these off and new ones will grow, some with branches + extending from them with more leaves on them. + +2. Make sure you water them regularly so that the top of the soil never dries + out. + +3. Insert Jobes Plant Spikes every two months. (refer to the back of the + package for instructions/information). + +4. Spray them regularly and gently with the miracle gro solution from about a + foot away. Make sure you spray the entire plant. + +5. Keep them nice and warm with the use of a phosphorous plant bulb. + + How many bulbs you actually use depends on how many plants you intend to + grow. If you have more than four plants I suggest you get two dual bulb + lighting fixtures. Ya know, the long bulbs. Put white bulbs in one and the + other flourescent bulbs. Keep the white bulbs on them during the day and + the flourescent ones on during the night. Perhaps two phosphorous coated + plant "show and gro" bulbs directed at the plants will help, too. Of + course if you only have two or three plants the two phosphorous bulbs is + really all you need. Those and maybe a ultraviolet bulb for at night. You + might also want to line the area where the plans will be with tinfoil. It + helps reflect the light. + +6. If the leaves on the very top of the plant start to curl up and turn + brown I suggest not having as many lamps on the plant or to not have + the bulbs on as long each day. + + Important Note: You want to keep the top of the plant at least a foot away + from the bulbs because they can catch fire and burn down. + When they get taller you might want to keep the bulbs on + them not as long as you used to. You can buy a timer to + turn the bulbs on and off at regular intervals. I suggest + you don't let the plant grow taller than four or five feet + anyway. Just stunt the top every now and then so that it + doesn't get any taller. Also, this way it will grow out + rather than up so you will have a nice fat plant in a small + amount of space. And always remember: Kill the males and + keep the females else the males will fertilize the females + and they won't bud. How to recognize the males from the + females? Well, for one: the male grows faster I believe. + Don't quote me on that. Other ways to spot it: Go pick up + a book on cannabis savita. That, I am sure, would tell you + better than I could. Last but not least: The roots are + always growing and probing deeper for water so you must + water it regularly to prevent out of control root growth + and this way you won't have to put it in bigger pots as + often. I would say that a pot with a 2 to 2.5 foot circumf- + erence is as big a pot as you will need for the plant. + +Optional: Play your plant some soft mellow music. Leave the stereo on fixed + on a station like WMJX or something. Don't keep it too loud, though. + +Part 4: Preparation of the plant for 'consumption' + +This is easy. Pluck the buds and let them dry out. Then smoke them. Most +people say: "hang the buds upside down to dry" I say no, don't do that. Just +lay them flat on a piece of wax paper or something. If you hang them all the +resin will go to the top of the bud and you will have killer weed at the top +but the rest of the weed will be so-so. If you lay them flat it assures even +distribution of the resin throughout the bud. Make sure you clean the buds +and remove all the seeds before smoking so you can assure yourself of a nice +smooth high and have the seeds for the second generation. + +Part 5: Security and safety measures. + +Yes, folks, the cultivation of Mary Jane, wrongfully so, is still illegal. So +we must keep on our toes to avoid an unwanted confrontation with the blue man. +This is what I suggest you do to ensure the safety of you and your plants: + +1. -NEVER- leave ANY paraphanelia laying around. This includes pipes, bongs, + papers, roach clips, high times, screens, suture removers, seeds, the plant + itself, etc. A lot of marijuana busts happen because of the man being there + for some other reason and then they see something like a pipe, or roaches + in an ashtray. + +2. Burn incense regularly, especially before/after/during getting high. This + will help cover up the unique smell of the smoke and the plant(s) growing + in your closet. You can also regularly dump a cheap but strong cologne + NEAR the area (NOT in the area) where your plants are growing to help kill + the smell once they start to bud. + +4. Keep any plugs used for the lights hidden yet readily accessible in case of + a visit by the man so you can unplug them. A light in a closet or somewhere + where there really shouldn't be one might attract attention. + +5. Just use common sense, if you have any. + +Part 6: Criminal Minded's mini guide to enjoying your plants! + +Now for some REAL entertainment!! + +I, as a proud member of the cannabis culture, have music, movies, videos, TV +shows, places, etc, that I enjoy mixing with marijuana and here I present to +you a list of them. I have also compiled a list of different names for +Cannabis Savita (with the help of Wavy Gravy in a High Times article - that is +what I remember of them), and some other lists. + +My top albums to listen to when stoned: + +1. Pink Floyd: Dark Side Of The Moon +2. Roger Waters: The Pros And Cons Of Hitchhiking +3. Pink Floyd: The Final Cut +4. Pink Floyd: The Wall +5. The Doors: Greatest Hits +6. Led Zeppelin: -Any- album + +My favorite music videos to watch when stoned: + +1. Any Floyd/Waters/Gilmour +2. November Rain - GnR +3. Wicked Game - Chris Isaak + +My top songs to listen to when stoned: + +1. Pink Floyd: Time +2. Roger Waters: The pros and cons of hitchhiking, part 10 +3. Pink Floyd - Breathe reprise +4. Pink Floyd: Comfortably numb +5. Pink Floyd: Not now John +6. The Doors: Riders on the storm +7. Led Zeppelin: Stairway to Heaven/All my love/Fool in the rain (3 way tie) + +My favorite lyrics to ponder when stoned: + +1. "I was standing on the leading edge. Jump! said Yoko Ono. I'm scared and + too good looking I cried. Go on she said. Why don't you give it a try? + Why prolong the agony, all men must die" (The Pros And Cons Of Hitch- + hiking, Part 10 - Roger Waters) + +2. "Ticking away the moments that make up a dull day you fritter and waste the + hours in an off hand way. Kicking around on a piece of ground in your own + town waiting for someone or something to show you the way. Tired of lying + in the sunshine staying home to watch the rain you are young and life is + long and there is time to kill today and then one day you find ten years + have got behind you no one told you when to run, you missed the starting + gun and you run and you run to catch up with the sun, but it's sinking and + racing around to come up behind you again. The sun is the same in the + relative way, but you're older and shorter of breathe and one day closer + to death. Every year is getting shorter, never seem to find the time. + Plans that either come to naught or half a page of scribbled lines. + Hanging on in quiet desparation is the English way. The time is gone the + song is over, thought I'd something more to say..." (Time - Pink Floyd) + +3. "Home, home again. I like to be here when I can. When I come in cold and + tired it's good to warm my bones beside the fire. Far away across the + field the tolling of the iron bell calls the faithful to their knees to + hear the softly spoken magic spells" (Breathe Reprise - Pink Floyd) + +4. "We watched the tragedy unfold. We did as we were told. We bought and sold. + It was the greatest show on Earth. But then it was over. We oohed and + aahed. We drove our racing cars. We ate our last few jars of caviar. And + somewhere out there in the stars a keen-eyed lookout spied a flickering + light. Our last hurrah. And when they found our shadows grouped around + the TV sets they ran down every lead they repeated every test. They + checked out all the data on their lists and then the alien anthropologists + admitted they were still perplexed but on eliminating every other reason + for our sad demise they logged the only explanation left. This species + has amused itself to death" (Amused To Death - Roger Waters) + +My favorite TV shows to watch when stoned: + +1. COPS +2. Sightings +3. In Search Of +4. Ren And Stimpy + +My favorite lines from songs: + +1. Getting high all the time hope you all are, too - Edgar Winter +2. Everybody must get stooooooned - Dylan +3. Legalize it - Peter Tosh +4. Flyin' High Again - Ozzy + +My favorite things to do when stoned: + +1. Watch/Listen to a severe lightning/thunder storm +2. Watch any of the videos/movies/TV shows listed in this tfile. +3. Listen to any of the music listed in this tfile +4. Be any of the places listed in this tfile +5. Just relax and enjoy the high + +My Hemp Hero: + +Wavy Gravy, The Clown Prince Of Pot. + +The "I Smoke Pot And I Have The Balls To Admit It" Award Goes Out To: + +The Black Crowes for performing with a 48 foot x 24 foot banner with a huge +marijuana leaf on it. + +My favorite movies to watch when stoned: + +1. Pink Floyd: The Wall +2. The Doors +3. Altered States +4. Jacob's Ladder +5. The Hustler/The Color Of Money (tie) + +Favorite sports to play when stoned: + +1. Pool +2. Darts + +Favorite Munchies Food: + +1. Junk Food/Chinese Food/Chocolate/Anything! + +My favorite places to be when stoned: + +1. On a boat out in the middle of the ocean +2. An island +3. The beach at night +4. Mainly outdoors + +Favorite Smoking Paraphanelia: + +1. My water bong, Owen +2. My wooden and clay pipe +3. My stone and brass skull pipe + +What I hate doing when stoned: + +1. Staying indoors +2. Reading +3. Falling asleep +4. Working +5. Programming + +Favorite beer to go with Mary Jane: + +1. Budweiser, of course. + +What I do best when stoned: + +1. Come up with creative writing ideas +2. Be lazy +3. Eat + +Hemp Aliases: + +Boo, Grass, Green, Ganja, Gaje, Thunderfuck, Cheeba, Hooch, Smoke, Herb, +Pot, Dope, Weed, Mississippi Mud, Tea, Mary Jane, Spliff, Herbals, Skunk, +Cannabis, Cannabis Savita, Brick, Bread.... + +well, that's only a little over half of them...feel free to add a name to the +list and stick your name at the bottom under the part that says: + + "Contributions:" + +Anyway, I hope you enjoyed this one time text file and that you gained what +knowledge you needed to grow your own Mary Jane at home. I wish you all the +best success and don't forget to live by the "Crimmy Golden Rule": + + "Call No Man Happy Who Is Not Baked" + + -CM + +Two more great sayings: + +"God created Marijuana so smoke a joint for Jesus" + +"Married to Mary Jane: Such a sweet commitment it is..." + +OF COURSE *I* said those.... + +Well, this is it...greets go out to: + +Jon, Erica, M, Apoc, Eric, Al, Oz, Roche, Todd and all the other smokers out +there! + +"Greets To People I Don't Know Personally But Must Mention Anyway" Dept: + +Pink Floyd, Roger Waters, The Black Crowes, Ozzy, Edgar Winter, Living Colour, +Bob Dylan, Led Zeppelin, Peter Tosh and all you other musical greats! + + -AND- + +Hats Off To The Man: Wavy Gravy! + +The Clown Prince Of Pot/Woodstock Announcer & Chef/Bob Dylan Room-mate/Hemp +Activist/Beatles Marijuana Dealer/and just an all around dude! + + -*- Criminal Minded -*- + +============================================================================= + +If you feel you have contributed something useful to this tfile please type +your name/handle/inet address below and what you contributed... + +============================================================================= + +CONTRIBUTIONS: + + + + + + + + + + + + +============================================================================= diff --git a/textfiles.com/drugs/mcdermit.txt b/textfiles.com/drugs/mcdermit.txt new file mode 100644 index 00000000..3597feec --- /dev/null +++ b/textfiles.com/drugs/mcdermit.txt @@ -0,0 +1,528 @@ +McDermottÕs Guide to the Depressant Drugs + +(c) Peter McDermott, 1993 +(c) Lifeline Project, 1993 + +This guide was first published by Lifeline Project, Manchester, UK. +This electronic version may be freely distributed electronically or as +hard copy. However, be warned that you are missing out on Mike +LinnellÕs brilliant illustrations. + + + +Introduction + +Since the emergence of the rave scene, drugs agencies have been falling +over themselves to court the hip young Ecstasy, Acid and Speed user, thus +neglecting a major staple of good problem drug users everywhere Ñ the +depressants. + +Once again, sixties drug trends are repeating itself, as danced-out +paranoid psychotics begin turning to those old favourites, the opiates, the +benzodiazapines and the barbiturates in an attempt to unwind after a period +of manic drug use, while on housing estates all over the north west, the +true afficionado of quality intoxicants keeps the faith with a tenner bag +of brown or a fist full of jellies. + +Without further ado then, for the sake of those suffering from pain, +anxiety or insomnia, let us take a trip down memory lane and try to +discover what effects the various types of depressant drugs might have. + + +Opiates + +Opiates is a term used to refer to any drug with an opium-like action, +whether they be derived from the opium poppy, like morphine, or synthetic +drugs made in a chemistÕs laboratory. + +All opiate drugs have similar effects. At low doses they relieve pain and +anxiety, and if the dose is increased, they produce a sedative effect Ñ a +good nod. + +Opiates also give us the classical model of addiction. Used regularly, they +produce tolerance Ñ a need to continue increasing the dose in order to get +the same effect, and stopping after repeated use produces withdrawal +symptoms Ñ physical discomfort and a mental craving for the drug. + +Commonly available opiates include: + +Heroin (Diamorphine Hydrochloride) Ñ This is the daddy of all +opiates, highly prized among opiate users because the drug has the minimum +undesirable side effects and a far superior euphoric potential to other +opiates. Heroin comes in several different forms. + +Pharmaceutical heroin Ñ A staple of the British drug scene in the days +when BritainÕs heroin scene was limited to a couple of hundred whinging +middle-class junkies who all lived in the toilets at Piccadilly Circus Ñ +this is now a rare, but increasingly available treat. During the sixties, +it was available either as a white powder (from pharmacy and hospital +thefts) and in ÔjacksÕ, 10 mg tablets made specifically for injection. The +form that is most often spotted today is the Ôdry ampÕ, an injectable +preparation that can occasionally be bought in 10 mg, 60 mg, and the highly +sought after 100 mg ampoules. These are the drug equivalent of the holy +grail for serious opiate users, but you need to be very careful. If you +shot one of those up thinking that it was probably about as strong as a +methadone ampoule, you could end up seriously dead. + +Far Eastern Heroin Ñ As the number of users increased and the law was +changed so that heroin was only available from special drug clinics at the +end of the 1960Õs, the market in prescribed heroin began to dry up. The +demand for heroin was partly met by the newly-imported ÔChineseÕ heroin. +This came in one of two types, and sometimes had brand names that the drug +had been given by the producers. Pink Elephant, Tiger and Rice Brand were +all very popular on Gerard Street during the early seventies. + +This heroin is also graded by number. Number 3 is a pinkish-greyish +granular substance that resembles instant coffee. Although produced for +smoking, it dissolves for injection when heated. Number 4 is a pure white +powder that closely resembles pharmaceutical heroin. This form is produced +for injection and the powder dissolves instantly on contact with cold +water. Although this is still available in many parts of the world, these +forms are rarely seen in Britain today. Most of the available heroin on the +black market is + +Middle/Near Eastern Heroin Ñ This is the ubiquitous ÔbrownÕ, that +dominates both British and Dutch heroin markets. In fact, this stuff isnÕt +actually heroin at all. True heroin is Diamorphine Hydrochloride Ñ a +hydrochloride salt. The brown that is sold in the U.K. is Diamorphine base. +Just as Crack is the free base of Cocaine, i.e., Cocaine that has been +prepared for smoking by removing the hydrochloride part, so the brown +heroin is a smokable product that is not soluble in water like real heroin, +but must be dissolved in some form of acid before it can be injected. +Dirty, smelly, messy stuff, that is a far inferior product to all of the +above. So who wants to throw in for a bag? + +In BritainÕs big cities, heroin currently dominates the market in opium- +derived opiate drugs. From time to time, ÔfanciesÕ like raw opium or +morphine ampoules appear, but always in limited quantities. In relation top +other opiates, heroin is more efficient than morphine, and morphine is more +efficient than opium, but once they get inside your body, they are all +converted to morphine anyway, so the effects are much the same. The only +place that any distinction can be discerned is in the rush, if the drug is +injected intravenously. Morphine and opium may produce more nausea, or more +itching, but they all do much the same thing. + +Heroin is usually taken in one of two ways Ñ it is either injected or +smoked. Smoking is by far the safest way of using as injecting makes you +much more liable to the risks of infection or overdose. The risk of +overdose is further amplified if the heroin is mixed with cocaine. Although +the two drugs might seem to cancel each other out, in fact, they appear to +potentiate each other, so the sum is greater than itÕs parts, so if you are +used to heroin and you do try a speedball, make certain that you use less +heroin than you normally would. + +Though heroin dominates the market for opiates, the price is expensive. +After all, the mafia have to pay for those stretch limosines somehow, and +how else is your dealer going to afford a BMW and a cocaine habit if there +isnÕt an enormous profit on the gear? + + +Methadone + +To cater for those of us seeking to starve the dealers, a newer product is +becoming more widely available. Methadone was originally developed by the +NaziÕs during World War II. When the supply of opium was cut off, Nazi +smackheads like Goering wanted to avoid the possibility of withdrawal, so +he instructed the German drug companies to produce a wholly synthetic +opiate that didnÕt need to rely on the poppy. With typical Teutonic +efficiency, the chemists came up with a drug that not only worked, but also +lasted a long time. As a result, Methadone has become the drug of choice +for doctors who are trying to help users manage their opiate dependency. +Heroin wears off after a couple of hours, thus requiring several hits each +day. Methadone, on the other hand, lasts anywhere between 24 and 72 hours, +depending on the dose that you take and on your individual metabolism. + +Methadone comes in several forms Ñ 10mg ampoules, 5 mg tablets, Methadone +Linctus Ñ 1 mg in 2.5 ml or Methadone Mixture DTF Ñ 1 mg in 1 ml. Again, +very rarely somebody will break into a chemist and pharmaceutical methadone +powder will come onto the market. This stuff is very, very strong, so if +you ever happen to come across it, be extremely careful how much you use, +especially if you are only used to street smack. + +Many users claim that the problem with methadone is that it lacks heroinÕs +intensity. It doesnÕt give you the same rush when injected and many users +believe that the high is inferior compared to heroin. How much of this +resistance to methadone is psychological is unclear. Many users become +obsessed with the rituals of drug use Ñ cooking up a hit, or rolling a bead +around the foil. + +In blind trials, users who were given both drugs orally were unable to +distinguish between the effects of the two drugs. Where heroin does have a +real advantage over methadone is in withdrawal. Withdrawal from heroin +should be over after seven to ten days. Withdrawal from methadone though, +can take up to a month or even longer. + +Any discussion of the properties of Methadone must also be an appropriate +place to warn of the dangers of Cyclazine. In an attempt to replicate the +effects of a now almost defunct drug called Diconal, desperadoes of the +drug scene have been known to mix certain travel sickness pills with +methadone ampoules before injecting them in an attempt to produce a +Diconal-like rush. In fact, the use of this combination just produces self- +destructive Martians whom all right-thinking junkies shun because of their +tendency towards compulsive and chaotic behaviour. In the past, I have +watched many a time-served junkie who after managing to keep it together +for many years, eventually fell to pieces after discovering Cyclazine. +Hopefully, as the Diconal experience retreats further and further back into +the annals of folk memory, fewer people will experiment with this +combination, but until then, I can only make one recommendation with regard +to this substance Ñ avoid it like HIV (or the plague.) + + +The best of the rest + +There are a whole bunch of other weird and wonderful opiates in the British +National Formulary, some of them organic, others totally synthetic. If you +are serious about pursuing a career as an opiate user, the chances are you +will come across them all at some point or another. Here are some of the +more common ones. + +Diconal Ñ If pharmaceutical heroin is holy grail of opiates, then Diconal +is the Lost Ark of the Covenant. For everybody who tried them, Diconal +immediately became the drug of choice. Diconal is a drug cocktail with the +most amazing rush known to man. Unfortunately, in accordance with the great +cosmic law of nish for nish, it also happens to be one of the most +destructive forces known to man. The drug comes in pink tablets that are +made from silicon rather than the more benign chalk base. After a couple of +hits, your veins become filled with sand and get as hard as glass. Keep on +injecting and you end up with abcesses and ulcers at best, and amputated +limbs if you are unlucky. Thankfully for us all, creative intervention on +the part of the ACMD meant that doctors needed a special license to +prescribe Diconal to addicts now means that Diconal are currently as rare +as hensÕ teeth. + +Palfium Ñ Because it is a strong drug, Palfium has itÕs fans, but +personally, IÕve never been among them. This drug is known primarily for +two things Ñ dirty hits and overdoses. For some reason, Palfium seems to be +very unpredictable. You can use say four tablets one day, then, the +following day you just try three and end up having blue and slumped against +a wall. Thumbs down. + +MST Continuous Ñ If you do like to take tablets then these are the +business. MSTÕs are Morphine Sulphate Tablets produced in a time release +format. These will keep withdrawals at bay for many a long hour, due to the +way that the tablet is manufactured. The particles of drug are enveloped in +wax particles of different sizes and densities, so the drug is continuously +released over a 12 hour period. This production process makes the tablets +difficult to inject as there is no apparent way to seperate the morphine +from the wax. Do you really want to shoot half a Latin Mass up your arm? + +DF118Õs, Di-Hydro Codeine Ñ DHCÕs are popular with people who have a +small habit and are looking to withdraw. If you fall into this category, +then DHCÕs are ideal. However, iof you plan to use them long term, there +are serious drawbacks. Due to the effect that opiates have upon gut +motility (your ability to shit), the combination of opiates and chalk in +DHC can make you extremely constipated. If you are being maintained or you +have a large habit, think seriously about changing to methadone. Chronic +constipation can be a serious health risk, as well as depriving you of one +of the greatest pleasures in every junkieÕs life Ñ discussing the state of +oneÕs bowels. + +Temgesic Ñ in places like Scotland where the heroin supply is erratic, +there is a greater reliance upon various pills. Temgesic grew in popularity +because for a while, the medical profession thought that they had little +potential for misuse. In fact, because they were designed to dissolve by +being placed under the tongue, it was discovered that they were quite a +reasonable tablet to inject as they were not laden with chalk. + +The strange thing about Temgesic is that they are an opiate antagonist. +This means that if youÕve got a smack habit and you do some Temgesic, +youÕll end up in withdrawal. On the other hand, if you donÕt have a habit +at all, they have an opiate like effect. They have become popular with +injectors who lack access to ÔrealÕ injectable opiates in places like The +Outer Hebrides. + + +Barbiturates + +During the seventies, the Ôbarb freakÕ was probably the most regular punter +at street drugs agencies like Lifeline. This was because they tended to be +those drug users who were least able to take care of themselves. Even the +most desperate bagheads look down upon barb freaks because of the mess that +they invariably get themselves into. + +Barbiturates are a sedative drug. Normally prescribed to induce sleep, +their use is now almost completely discontinued for this purpose, though +milder variants such as phenobarbitone may still be used to manage +epilepsy. Nevertheless, Barbiturates occasionally turn up from time to +time, usually as + +Sodium Amytal - most frequently as a bright blue capsule that contains +60 mg of the drug. + +Seconal Ñ 50 mg orange capsules, and finally + +Tuinal - which are a cocktail of 50 mg of Amytal and 50 mg of Seconal +which, unsurprisingly perhaps, come in a capsule that is half Amytal blue, +half Seconal orange. Whoever was responsible for the design of these +capsules certainly had a flair for marketing substances to junkies and +hypochondriacs. + +The first thing to get clear about barbiturates is that these things are +dangerous. I donÕt mean ÔHeroin screws you upÕ dangerous, I mean seriously +fucked-up style dangerous. Is that clear enough for you? During the +seventies, around ? people died every year as a result of barbiturate +poisoning. Many of those deaths were people who just took the drug to +sleep. + +The pattern usually went like this. Have a few scoops to help you get your +head down. Then, drop a couple of nembies and pour yourself another drink +while you wait for the drug to take effect. After a while, you donÕt +remember whether you took the caps or not, so youÕd better take a couple +more to be on the safe side. TheyÕd find your body in the morning. If you +hadnÕt choked on your own vomit, your breathing had slowed down +progressively until it stopped. + +Like opiates, barbiturates are addictive, only more so. Taken to help you +sleep, after a few days, it becomes impossible to sleep without them. Like +the opiates, barbituates produce tolerance so that you need to keep upping +the dose to get the same effect, but the real hum-dinger is the withdrawal +syndrome. If withdrawal from opiates is cold turkey, then withdrawal from +barbiturates could be cold raven. Besides the craving, discomfort and +inability to sleep, barbiturate withdrawal also causes major epileptic +seizures. Nobody dies from opiate withdrawal, but it is a strong +possibility with barbiturates and you should only think about it under the +supervision of a doctor, preferably as a hospital in-patient. + +The possibility of overdose is amplified greatly if barbs are injected into +a vein rather than taken orally. By and large, it is usually only those +people who have had their switches set to automatic self-destruct mode who +use barbiturates because the drug isnÕt at all pleasant or enjoyable. Barbs +lack the euphoric content of opiates and the social lubricant properties +associated with alcohol. They simply produce a dark, blank oblivion and as +such will always remain popular with those people who hate themselves or +their lives so much that their behaviour is governed by a compulsion to +obliterate all possibility of thought and self-examination. Do yourself a +favour. Just say no. + + +Benzodiazapines + +When it became clear that large numbers of people died each year simply as +a result of trying to cure insomnia, the drug companies spent a vast amount +of money in an attempt to discover a replacement for the barbiturates. +Eventually, the pharmaceutical industry came up with the Benzodiazpines. +Eureka! No side-effects, they said. Non-addictive, they said. Safe, they +said. Unlikely to be misused, they said. Loads of money, they said. (Much +more quietly, to stockholders, in boardrooms.) + +Like opiates and snake oil before them, Benzodiazapines were marketed as +being good for whatever ails you Ñ the original mothers little helper. If +you go to the doctor and tell him that youÕve lost your job, your wife had +left you, your dog has died and your next door neighbour keeps giving you +funny looks, the chances are, that heÕll write you a prescription for +benzodiazapines. Well, five or six years ago, he would. At the moment, +doctors and the drug companies are being sued by thousands of people who +allege that they have suffered from the side effects of benzodiazapines, so +now they think twice about it. Then write the prescription. + +They tend to be divided into two major types. Some are used as hypnotics or +sedatives, drugs that are used to induce sleep in insomnia. Benzodiazapines +in this category include + +Nitrazepam Ñ Nitrazepam are a long-acting benzodiazapine hypnotic. Before +doctors were forced to prescribe the generic equivalent of a drug, +Nitrazepam were possibly the most commonly used sleeper in the U.K. Sold as +ÔMogadonÕ, they were the sleeping tablet with the smiley face. In recent +years, their popularity seems to have been massively outstripped by the +shorter acting benzodiazapine hypnotics, the most popular being + +Temazepam Ñ Also known as eggs, jellies, temazzies, norries, rugby balls +and a host of other pseudonyms, Temazepam seem to be the drug of choice for +the treatment of insomnia. They have also replaced the barbiturates as the +self-destructive drug userÕs intoxicant of choice. We will discuss this +substance at some length a little later. + +Other hypnotic benzodiazapines include Flunitrazepam, Flurazepam, +Loprazelam and Triazolam. They all have similar effects. Triazolam +(also known as Halcyon) have recently been taken off the market because of +concern over the side effects. So much for safe! + +The other major use for benzodiazapines is as anxiolytics Ñ drugs that +reduce the anxiety levels of the user. The most commonly used +benzodiazapines of this type include + +Diazepam Ñ Also known by the trade name, Valium + +Lorazepam - A short-acting anxiolytic, also known as Ativan + +And a whole host of others with very similar effects, including +Alprazolam (Xanax), Bromazepam, Chlordiazipoxide (Librium), +Clobazam, Chlorazepate Dipotassium (Tranxene) Medazepam and +Oxazepam. + +Regardless of which particular benzodiazapine is being used, the side- +effects seem to be much the same. Some experts feel that the shorter-acting +benzodiazapines like Lorazepam (Ativan) are more addictive and more +difficult to withdraw from than the longer-acting types such as Diazepam. +For this reason, many doctors recommend substituting Diazepam in any +detoxification programme. + +All benzodiazapines depress the breathing and so if taken with opiates or +alcohol, can result in death from respiratory failure. They should be used +with caution by anybody who is pregnant or who may have suffered from +hepatitis or any other kidney or liver problems. + +Taken over a longer period, these drugs can make you crazy. Besides +becoming addicted, you can become paranoid, agoraphobic (frightened of +leaving the house) or develop obsessive/compulsive patterns of behaviour. +Still, if it ever happens to you, at least youÕve got the consolation of +suspecting that itÕs probably a result of the weird, mind-bending drugs +that youÕve been taking. Imagine how it must feel to be a straight +housewife, getting a terrible habit with all these wierd side effects, +which you got from the medicine that your doctor gave you to help you cope +with the depression that you felt when you found your husband was fucking +his secretary. Just a little something to help you sleep, my dear. OoooÑ +eeeÑooo! + +At the moment though, the most popular benzodiazapine must be Temazepam. +Temazepam use is on the increase among several different constituencies of +drug user. Due to a lack of real MDMA on the club scene, amphetamines, LSD +and other, longer-acting psychedelics like MDA currently dominate. As a +result, many club-goers have taken to using the little green and yellow +Rugby Balls in an attempt to get some sleep. Smoking a reefer is a much +less hazardous method of chilling out, but if you must use benzodiazapines +to get to sleep, then donÕt take more than one and donÕt use them +regularly. Once a week is probably still too often. + +Hard-core cocaine and rock users are also turning to Temazzies to soften +the crash when the charlie or the rock is all gone. The same messages apply +here. Using weed or even alcohol is a much safer strategy, but if you must +use them, then do make sure that you stick to occasional oral use. Your +cocaine use is probably a problem already Ñ try not to make it worse by +getting another habit. + +The final group who are using Temazepam are injectors who probably prefer +heroin, but use Temazzies because they canÕt afford to score, or because +their tolerance is such that supplementing their script with Temazepam is +the only way they can work up a good gouch from their methadone. If this +description applies to you, then you are probably at enormous risk from the +impact of Temazepam on your life, your health and your social status. Even +the worst smackheads look down on a Temazzie user. + +BenzoÕs reduce inhibitions, making some people aggressive, but the lack of +co-ordination that the drug produces means that you are more likely to get +a pasting. +Some people feel that the Dutch courage that benzodiazapines produce is +actually a cloak of invisibility, even invulnerability. They might go out +shoplifting, believing that nobody will be able to see their subtle moves +as they swiftly teleport the goods into their stash. In actual fact, the +store detectives are thinking, ÔIf this shop thinks that they pay me enough +to apprehend that dirty, stinking AIDS victim, theyÕve got another think +coming. Phone for the man with the big net and the tranquillizer gun.Õ + +Due to the way that the benzodiazapines reduce inhibitions, some people +view downers as an aphrodisiac. (Remember ÔMandies make you randy!Õ) In +fact, this is a myth that is perpetuated by rapists. (ÒErr, they were a +good hit them Temazzies, but they havenÕt half given me a sore arse!Ó) +Using any downer decreases your self control. Given the role that sex plays +in the transmission of the HIV virus, everybody needs to maximize the +amount of control that they exercise whenever there is the possibility of +sexual contact Ñ downers and fucking just do not mix. + +The same is true of injecting. Like the barbiturates before them, Temazepam +have become popular among certain sections of injecting drug users. +However, the risks associated with this drug are far greater than the risks +associated with heroin. As with sex, the drug minimizes the control that +you have over your injecting behaviour. This may lead you to forget which +syringe belongs to who. Have you cleaned it out? You may even forget all +about the need to stay safe and not share other peopleÕs works. You +probably couldnÕt care less Ñ drugs like Temazepam make you feel +invulnerable while you are under the influence. + +Temazepam also creates other risks for injectors. In order to stop people +injecting the eggs, the drug company filled them with a solid gel in an +attempt to prevent the drug from passing through the needle. People got +around this by warming the gel and diluting it with water. However, now +when it hits the vein, it resolidifies, causing thrombosis. This can lead +to Deep Vein Thrombosis, serious abscesses and ulcers. Should you miss the +vein and inject into an artery, you will probably develop gangrene, which +often results in the loss of a limb. Injecting temazepam, or any other +tablet or capsule come to that, is not a good idea at all. + + +Alcohol + +When considering the depressant drugs, few people pay suficient attention +to alcohol. Alcohol has very paradoxical effects Ñ in small doses, it acts +as a stimulant, but after a few more drinks it acts as a depressant. While +some experts believe that a couple of glasses of wine a day may improve +your health, larger amounts are definitely not good for you. + +Just because a drug is legal, it doesnÕt mean that it is safe. Like all of +the other depressant drugs, alcohol is addictive. Unlike the opiates, +alcohol causes damage to various organs. Brain damage and cirrhosis of the +liver are just two serious potential side effects. Contrary to popular +opinion, you can also overdose on alcohol. Every year there are a sizable +number of deaths from alcohol poisoning Ñ generally when young people who +are unused to drinking start drinking spirits. With beer and wine, the +volume that you have to drink to get rat-arsed helps you to titrate the +dose Ñ take the drug in successive small doses (i.e. pints) until you reach +the effect that you desire. With spirits, you can easily pour half a bottle +or more down your neck after earlier drinks have rendered your taste buds +inactive Ñ before you know it, you are in a coma. + +Another crucial fact to remember about alcohol is that it potentiates the +impact of all the other depressant drugs. Alcohol is a contributory factor +in a majority of deaths from drug overdoses. Opiates like heroin depress +the respratory system Ñ they slow down the rate at which you breath. +Alcohol has the same effect. Mix the two together, and you may find that +your breathing slows down to the point of stopping. This bad enough if it +happens in company, but at least they can attempt to resuscitate you or +call and ambulance. Very often, you are O.K. while you are out with your +mates Ñ the problem occurs when you sink that last pint at closing time and +then go home to bed. Alcohol doesnÕt produce itÕs full effect until some +time after you have taken it Ñ so you always feel a couple of drinks behind +your consumption. Go home, hit the pillow, and the next morning your +partner wakes up next to a stiff. + +The other problem with alcohol, is that it also produces nausea. Likewise, +the opiates. So once again, the two drugs enhance each otherÕs side- +effects. Pulmonary oedema Ñ drowning in your own vomit Ñ is the second +major cause of drug related death and alcohol is often a major +contributory factor. + +Personally, I think it best to avoid the stuff altogether. Anybody who has +ever had Hepatitis B has already done serious damage to the liver Ñ alcohol +will make that damage far worse. The same is true of Hepatitis C Ñ although +the damage may not be apparent for some years to come. + +If you do drink, the liver works overtime in order to metabolize the +alcohol. If youÕve got a habit, the liver will also metabolize the drug at +a much faster rate than your body normally would, so you end up sick from +withdrawal much earlier than necessary. So, a sociable drink every now and +again is one thing, but if you do drink large amounts of alcohol on a +regular basis, then youÕre stirring up trouble for yourself one way or +another Ñ but if youÕve got a habit as well, then youÕre fucked, mate. + + +Summary + + +There is a whole lot of information in this booklet, so when it comes to +the depressants, what are the key points that we need to bear in mind? + +1. All depressants are addictive. If you must use them, try to limit your +use to occasional use. That way, you will maximize the effects and minimize +the cost. + +2. Injecting drugs raises the stakes enormously. The risks from HIV, +Hepatitis, Abscesses, Gangrene, Overdose are very high. It is best if you +can avoid injecting drugs. + +3. If you do inject drugs, only use drugs that are designed to be injected. +Follow safer injecting practices. + +4. Mixing drugs increases the risks enormously. Only use one drug at a +time. + +5. Alcohol is a drug too. Used in combination with other drugs, alcohol can +potentiate their side effects. Never drink and use other depressants +together. + +6. Some depressants reduce your self control. Remember, if engaging in +risky behaviour of any kind, control can mean the difference between being +alive and being dead. + + +(c) Peter McDermott, Lifeline, 1993 + diff --git a/textfiles.com/drugs/mda.txt b/textfiles.com/drugs/mda.txt new file mode 100644 index 00000000..be044f4b --- /dev/null +++ b/textfiles.com/drugs/mda.txt @@ -0,0 +1,163 @@ + + "The Love Drug" + + from "The Marriage Of The Sun And Moon" + + by Andrew Weil + + Houghton Mifflin Co., publishers, 1980 + + + + + MDA is known as the love drug in the American subculture +because of its reputation for producing loving feelings in groups +of people. The initials stand for 3,4-Methylene-dioxy-amphetamine +and the drug is a straightforward derivative of amphetamine, +first synthesized in Germany in 1910. Its effects on human beings +are much more interesting than simple stimulation. When I first +encountered MDA in 1970, I took it a number of times and since +then have observed its effects on a great many people. + + The usual dose of MDA is 90 to 150 milligrams, taken orally +in a capsule. Its effects become apparent in twenty to sixty +minutes and persist for ten to twelve hours. People perceive the +onset of these effects differently. Some experience initial +nausea. Some feel a warm glow spreading through their bodies. +Most people become aware of a sense of physical and mental +well-being that intensifies gradually and steadily. MDA commonly +induces a state of profound relaxation and patience in which +anxiety and defensiveness are left far behind. "It is impossible +to imagine anything being a threat in that state," one user tells +me. + + Unlike most stimulants, MDA does not increase motor +activity. In fact, it suppresses it in a remarkable way, so that +people can remain comfortable and content in one position for +long periods. This effect is most dramatic in people who are +heavily dependent on coffee and cigarettes, who are always in +motion of one sort or another. Under the influence of MDA they, +too, can be calm and motionless. Pharmacologists call this the +"antikinetic" action of the drug, but that is a negative way of +describing something very positive. I prefer to call it a +centering action. + + The combined effects of relaxation and centering greatly +facilitate certain kinds of physical activities, such as yoga, +martial arts, and any disciplines requiring balance and +maintenance of posture. For example, i can maintain a headstand +longer when I take MDA than normally. Although it is extremely +pleasant just to lie still and enjoy a respite from nervous +activitiy in this state, i have tried rock climbing and swimming +after taking MDA and again find that my body works in a more +coordinated, smoother fashion and that I can do more than usual. +One novel experience, conferred temporarily by the drug, is the +ability to interact with kinds of external stimulation that would +ordinarily be painful and not get hurt. It may become poossible +to walk barefoot over sharp stones, for instance, and experience +no discomfort or injury, apparently because the muscles are so +free from imposed tension that they can respond with precise +counterpressure to the point of a stone. In this way, the skin +feels no net force. + + Such experiences confirm in a powerful way the sense of +well-being. It fels as if nothing is threatening, and, in fact, +things in the external world behave differently. This theme +carries through to interpersonal relations. When people feel +well, centered, unthreatened, and aware of their own strength and +loveliness, they are able to drop many of the usual barriers that +develop in groups. It is common in group MDA experiences for +people to explore mutual touching and the pleasures of physical +closeness. Participants may feel very loving toward one another, +but the feelings are not explicitly sexual because MDA tends to +decrease the desire for orgasm. For many people the experience of +enjoying physical contact and feeling love with others in the +absence of a specific hunger for sex is unique and welcome. (Some +people do use MDA to heighten sexual experience.) + + Other hungers and desires may also disappear int he MDA +state. Habitual users of tobacco feel no need to smoke. Chain +smokers of marijuana do not need their weed. Nail biters leave +their fingers alone. Compulsive talkers become quiet. Compulsive +eaters do not think about food. Moreover, this desireless +condition feels supremely natural and valuable. Becaue MDA +affects the senses minimally, everything appears as it does +usually. There are no hallucinations, illusions, or distortions, +simply a great aura of peace and calm. It is not possible to +pretend, as it often is with hallucinatory drugs, that the +experience is coming from without. Clearly, all of the important +effects, including the ability to be free of anxiety and desire, +are part of the human repertory, often unexpressed, to be sure, +but there nonetheless. + + The trouble with obtaining this state through the use of a +drug is that it does not last. After five or six or eight hours, +the old habits begin to creep back. before long the experience of +loving peace and desirelessness is in the past. The value of the +drug is that it can show people that certain ways of being are +possible and available; it gives no information about maintaining +them. + + I do not mean to paint a picture of MDA as a trouble-free +panacea. Like all psychoactive drugs, its effects vary greatly +with expectation and setting. People who take it in combination +wit alcohol and downers at wild parties with strangers are not +likely to realize its pootential. MDA also releases much energy +stored in the nervous system, so that those who take it often +feel tired and sluggish the next day. It should not be used +unless one is in good physical shape with adequate energy +reserves. For unknown reasons, it seems to be harder on womena nd +may activate latent infections or problems in the female +genitourinary tract. Women should take lower doses than men until +they are sure the drug agrees with them and should avoid the drug +altogether if their pelvic organs are ailing. Many people of both +sexes report that the drug causes tension of the muscles of the +jaw and face. In some individuals this effect becomes very +annoying, progressing to involuntary grinding of the teeth. All +of the adverse physical effects of the drug are dose-related. +Whenever I have interviewed people who have had bad experiences +with MDA, I have determined that they have taken excessive +doeses, been in poor settings, or taken other drugs masquerading +as MDA. + + In the right hands, MDA is quitte safe. Out of hundreds of +experiences with it htat I have observed, I have seen only three +anxiety reactions. The medical potential of the drug is great and +quite unexplored. I have noted repeatedly that people under the +influence of MDA, when feeling high, centered, and free of +desire, are in a state complete anergy - that is, they manifest +no allergic reactions, even to allergens to which they have a +lifelong sensitivity. Asthma disappears, hay fever disappears, +cat allergies go away, and there are even no responses to +mosquito bites. This effect is temporary and appears to be the +analogue in the body of the mental experience of complete +relaxation and lack of anxiety. It might be reproducible without +the drug if we could learn to spend more time in that state. I +can envision a training program in allergy control in which +patients would go through ten seesions with decreasing doses of +MDA in settings designed to maximize the centering effect and +demonstrate the possibility of coexisting with allergens. By the +tenth session the dose would be zero and pateitnts would be doing +it all on their own. + + Unfortunately, the federal government, having declared MDA +to be a drug with high abuse potential and no redeeming +therapeutic value, has placed it in a category (Schedule I) that +makes it unavailable to physicians and available to researchers +only with difficulty. I know of no ongoing research with MDA in +this country and consider this lack to be another result of +unenlightened policies on substances that could be helpful to us. + + :-:-:-:-:-:-:-:-:-:-:-:-:-: + The Convent Text Files BBS + 10 megs 3/1200 no password + 619-475-6187 + :-:-:-:-:-:-:-:-:-:-:-:-:-: + + +******* + + +Good Tokin'! + +  \ No newline at end of file diff --git a/textfiles.com/drugs/mda02.txt b/textfiles.com/drugs/mda02.txt new file mode 100644 index 00000000..3ca6ecbd --- /dev/null +++ b/textfiles.com/drugs/mda02.txt @@ -0,0 +1,46 @@ + +dir + 87Sep06 3:06 am from THE MAGI +DESIGNER DRUGS BASIC SERIES I : MDA XTC's older sister + XTC or methylenedioxy-methamphetamine gained noteriety last year as a designer + +drug included in a ban against designer drugs in general. It was lumped +together with some very dangerous heroin analogs and the lot of them made +Schedule I controlled substances. This was done under quite some protest as it +is a very mild hallucinogen similar to mescaline and being used by +psychotherapists at the time. It was known as the Love Drug in some circles +(just as MDA) as it's effects are very conducive to snuggling and getting +close to some- one. The following synthesis is for MDA banned during +the original drug scare days of the early 70's. XTC was a designer drug +because it was a chemical analog of MDA that was not on the books yet. + The basic starting material for MDA is the substance 3,4 methylenedioxy +benzaldehyde, also known as piperonal, and available in some herb stores as +heliotropin crystals (alongside their perfume oils). + The first step is to form the nitropropene. Do this by dissolving +approximately 40g of the piperonal with about 16g nitroethane in 150ml of +glacial acetic acid with 15g Sodium Acetate. Cool, filter,and purify by +recrystallizing from acetic or methanol. + + The next step is to reduce the nitropropene to the amphetamine +(Methylenedioxy-amphetamine) with a Zinc - Mercury amalgam prepared from 200g +of Zn and 20g HgCl(2) (Mercury Chloride). Suspend .2 moles of the nitropropene +in 2 liters of ethanol with the amalgam, and add with vigorous stirring +portions of conc. HCl until the yellow color disappears. Continue stirring for +one-half hour, filter, evaporate in vacuum to get freebase oil of MDA. + + Finally the Hydrochloride salt has to be formed to make it water soluble and +snortable, ingestable etc. Dissolve the oil in Dry Ether and slowly bubble dry +HCl gas through solution. Crystal precipitate will form. + + Production of : + + THE MAGIC THEATRE + + + + +From Lunatic Labs UnLtd. 415-278-7421 +Press a key... + +The PIRATES' HOLLOW 415-236-2371 ;( + diff --git a/textfiles.com/drugs/mdabrain.txt b/textfiles.com/drugs/mdabrain.txt new file mode 100644 index 00000000..7e948efb --- /dev/null +++ b/textfiles.com/drugs/mdabrain.txt @@ -0,0 +1,94 @@ + + + BRAIN DAMAGE AND MDMA + + + Two studies were used as evidence to support the emergency placement +of MDMA into Schedule I effective July 1, 1985. These were Woolverton +et al. and Ricaurte et al. (See references). The latter study was +not even done with MDMA, but rather with MDA. The DEA also recieved +a study from another group (Schmidt, Wu, and Lovenberg) done using +MDMA. I have not yet looked up the MDA paper, but I did find the +Schmidt, Wu, and Lovenberg paper (actually, it's only an abstract) and +I have some information on the still unpublished Woolverton et al. paper +from another reference (Shulgin, A.T.). The Woolverton et al. paper +should come out this year in a book. + + In the Schmidt, Wu, and Lovenberg study rats were given single injec- +tions (s.c.) of MDMA and killed 3 hours later to measure concentrations +of brain metabolites. From previous studies they knew that serotonin +levels decline and reach their minimum concentrations at 3 hours. Rats +given 2.5, 5, 10, and 20 mg/kg MDMA had striatial serotonin concentrations +that were 97%, 40%, 25%, and 25% of control rats 3 hrs. later. One week +after injection rats given 10 or 20 mg/kg MDMA still had "significantly +depressed" levels of serotonin. They don't say what the levels were, +though. + + Rats in the Woolverton et al. study were either injected twice daily +for four days with MDMA and killed two weeks later, or they were given +one dose and killed two weeks later. The dosages were 10, 20, 30, or +40 mg/kg. Rats that went on the MDMA binge all had "extensive decrease" +of hippocampal serotonin. A single injection at 40 mg/kg lowered sero- +tonin levels to 76% of just-say-no rats two weeks later. + + What does this mean to those of us who are not rats? Well, if you are +a Rhesus monkey, it means that if you take twice the lethal dose of +MDMA (LD 50 in Rhesus monkeys is 22 mg/kg) and survive, you will only +have serotonin levels that are 76% of your friends' who told you not +to do it. If you are sort of like a Rhesus monkey (like me) then it +means you can probably safely take 2.5 mg/kg of MDMA (orally, please) +and suffer only a 3% or so temporary drop in your serotonin levels. +For a 150 lb. human, 2.5 mg/kg is 170 mg. Most street doses are about +100 to 150 mg. Anyway, these studies will probably turn out to be +poorly done just like the ones done on LSD several years ago that +concluded that LSD caused chromosome damage. It turned out that if +you leave heavy amphetamine users out of the study, there is no evidence +of chromosome damage. Yes, I know, MDMA is an amphetamine. It just +means that you shouldn't overdo it. Even peanut butter has mutagens +in it (aflatoxins). + + Hugs and Kisses, + + Betelnut (Wierdo7) + + + + REFERENCES + + +Ricaurte, G.; Bryan, G.; Strauss, L.; Seiden, L.; and Schuster, C. 1985. + Hallucinogenic amphetamine selectively destroys brain serotonin + nerve terminals. Science Vol. 229:986-988. + +Schmidt, C.J. and Lovenberg, W. 1986. (+/-) Methylenedioxymethamphet- + amine (MDMA): A potentially neurotoxic amphetamine analog. (Abstract + 5264). Federation Proceedings Vol. 45: 1059. + +Shulgin, A.T. 1986. The background and chemistry of MDMA. Journal of + Psychoactive Drugs Vol. 18(4): 291-304. + +Woolverton, W.L. et al. 1985. Behavioral and neurotoxic effects of + MDMA and MDA. Abstract from the American College of Neuropsycho- + pharmacology Meeting, Honolulu. + + + + +From Lunatic Labs UnLtd. 415-278-7421 +Press a key... + + /////////////////////////////////////////////////////// + // The PIRATES' HOLLOW // + // 415-236-2371 // + // over 12 Megs of Elite Text Files // + // ROR-ALUCARD // + // Sysop: Doctor Murdock // + // C0-Sysops: That One, Sir Death, Sid Gnarly & Finn // + // // + // "The Gates of Hell are open night and day; // + // Smooth is the Descent, and Easy is the way.." // + /////////////////////////////////////////////////////// + + + +  \ No newline at end of file diff --git a/textfiles.com/drugs/mdaxtc.txt b/textfiles.com/drugs/mdaxtc.txt new file mode 100644 index 00000000..70a6ab3b --- /dev/null +++ b/textfiles.com/drugs/mdaxtc.txt @@ -0,0 +1,165 @@ + + MDMA(XTC) Notes + From the Recreational Drugs Sub-Board + On Lunatic Labs BBS - 415-278-721 - 1200/2400 Baud + +-------------------------------------------------------------------------- + +Title: a psychedelic peak experience +When: 3/28/89 at 5:57 pm +Left by Unknown Lab Rat + +...and that is the ultimate understatement. + +try: 400-500mics of lsd, followed 30-45 min later w/ 50-100mgs of XTC. + +mix w/ love and sex a successful attempt at mystical-spiritual transcendence. + +our life will never be the same again. we have added a dimension of +experiencing life and each other that we never dreamed possible. + +I just wish I could truly describe what happened, but words are inadequate. + +I usually dont encourage people I dont really know to do psychedelics or +certain psychedelic combinations, but this one is so utterly positive, I cannot +see anyone having a bad trip or not benefiting in a very personal manner from +it. + +go for it. + +SERPENT OF SANDOZ + +-------------------------------------------------------------------------- + +Title: XTC +When: 4/8/89 at 4:40 pm +Left by castalia (Level 49) + +hypothetically speaking, if any of you out there WERE doing X - which of course +you shouldnt be doing, it being a Schedule I substance and all - what would +have been the most interesting/fun/amazing/novel things youve done on it (or +plan to do on it)? just trying to collect some experiences for my archives +here - it occurred to me the other nite (last nite actually) that it is much +more fun doing certain things X'd than others, but I mite be wrong. so anybody +wanna share their deep dark secrets? +also, Im interested in X + some other substance(s) experiences. personally, an +X/LSD mixture for me has been the most mind-blowing drug experience ever, one +that truly changed my life... (the magic formula: 500 mics of LSD; when you +feel the acid coming on drop 50-100mgs of X and youre OFF. roundtrip ticket +across the universe. poetically speaking, the LSD provides a canvas for the X +to paint upon - while zipping around n-dimensional hyperspace...). +also, I think *any* amount of speed - esp. meth - should be avoided 24-48 hrs +before X'ing because the speed somehow seems to interfere w/ the potential +intensity of the trip.... any comments? + +-Castalia + + +-------------------------------------------------------------------------- + +Title: XTC +When: 4/9/89 at 1:07 pm +Left by Sir Countach (Level 49) + +Hmmm, I've X'd Before But Have Been Told By A Notable And Trustworthy Source +Who Did Some Of The Same As Me That It Wasn't That Great Of X, But None The +Less When I X I Like To Go For A Walk With A Cane Or Similar Object, It's Fun +To Just Twirl The Cane Around Inbetween Your Fingers... But On My Last X +Experiance It Was Spent Lying On A Floor With A Girl That I Was More Than Just +Quite Fond Of And Recieving A Back/Front Rub For Several Hours Which Turned +Into Into Some Other Things... It Was Great... We Ended Up Spending The Next +Three Days Together In Bed Getting Wired Until My `Roomate' Came Home And +Kicked Us Out Of Her Bed... Oh Well... + + +I've Also Recently Learned A Lesson About Coke/Crank... It Does Fuck Up Your +Nose, I'm Now Suffering From A Upper Respitory Infection And Have 1-2 Layers Of +Skin Burned Off Inside My Nostrils... I Guess No More Snorting Fro Me... Time +To Start Eating And Smoking It Again... Ugh! + +-------------------------------------------------------------------------- + +Title: XTC +When: 4/9/89 at 3:06 pm +Left by parabolic mike (Level 11) + +I'v never done any,but man do i ever want to try it. Anyone have a formula for +it? + +500 mics ehh cas', for a canvas ,must be somthin' + + >PM< + + +-------------------------------------------------------------------------- + +Title: XTC +When: 4/9/89 at 10:13 pm +Left by castalia (Level 49) + + making XTC is a little more complicated than a single formual and there +are all kinds of ways you can fuck it up... I definitely dont recommend it +unless youre a real experienced alchemist.... I know/correspond w/ alex shulgin +who originally synthesized MDA and MDMA (back in the 1920s) and I have all +kinds of interesting info on both of theses substances, if anyone's interested. + there's also a file on this board for an MDA recipe, but I cant +guarantee its accuracy, and I definitely know you cant get piperonal in herbal +stores anymore. + +-Castalia + + +-------------------------------------------------------------------------- + +Title: Extasy +When: 4/10/89 at 9:16 am +Left by Dexter Riley (Level 35) + +What I like to do is head out to some semi-nature spot good for hiking, then +just walk around exploring and talking with whomever I am tripping with. + +And I bring plenty of water... + + +-------------------------------------------------------------------------- + +Title: A friend o' mine... +When: 4/10/89 at 5:52 pm +Left by Pope Chuck Manson II (Level 39) + +Just told me about an uncomfortable experience he had on XTC.. he got back from +this Grateful Dead show on the stuff and his mom asks him where he was that +day, so he goes off at dinner time about the great atmosphere at Dead shows and +how there are sooooo many drugs there and everyone's really cool, and the whole +time his mom just sits there nodding, looking strange and going "Mmm-hmm." +while trying to smile... + + +-------------------------------------------------------------------------- + +Title: XTC+Meth +When: 4/10/89 at 6:16 pm +Left by Elric of Imrryr (Level 49) + + Well XTC and Methamphetamine are not a workable combination, it seems +that XTC(MDMA) and Methamphetamine compete for the some neurotransmitter sites +which pretty much results in burn-out. + XTC takes alot out of your body, so you should try to eat well and get +enough vitamins, minerals, amino-scids, and fluids both before and after you do +XTC. + Elric + + + +From Lunatic Labs UnLtd. 415-278-7421 +Press a key... + +Drugs:New Looks and Visions [lsd]: 17 of 97 + + + + +The PIRATES HOLLOW 415-236-2371 ;( + + +  \ No newline at end of file diff --git a/textfiles.com/drugs/mde_as_m.txt b/textfiles.com/drugs/mde_as_m.txt new file mode 100644 index 00000000..ded7c431 --- /dev/null +++ b/textfiles.com/drugs/mde_as_m.txt @@ -0,0 +1,100 @@ +From: u9264582@wumpus.cc.uow.edu.au (The RadioDog) +Newsgroups: alt.drugs +Subject: FWD : Analysis of current `extasy' +Date: 1 Feb 1994 09:54:42 +1100 +Message-ID: <2ik27i$4ro@wumpus.cc.uow.edu.au> + +Forwarded from the Ausrave mailing list + + ______________________________________________________________ + An Analysis of "Hearts", a Tablet Illicitly Sold as "Ecstasy". + ______________________________________________________________ + +Introduction: + +In recent months, observers have noticed an increase in the availablility +of tablets sold illicitly as "ecstasy", supposedly methylenedioxy +methamphetamine (MDMA), in Sydney. One form which has often been reported +is known as "Hearts", and appears as a white tablet about 0.5cm in +diameter, with a heart shaped emblem imprinted. A large number of these +tablets were made available close to New Years Eve. Some experienced +users claimed that the effect of the tablets was "smacky", i.e. +they thought that it contained heroin in addition to MDMA. + +Up until a few months ago, in the Netherlands, the MDMA analogue +N-ethyl methylenedioxyamphetamine (MDE, MDEA, Eve) was legal and +freely available. With the banning of this substance, it would seem +reasonable that the newly illicit stockpiles should have been distributed +around the world. In recent years, quality MDMA has been rare in +Sydney, and sales of adulterated or forged samples have correspondingly +been rife. However, there have been persistant rumours of recent +"ecstasy" supplies having their origin in the Netherlands, and indeed +this has been used as a marketing point; people tending to believe +that if it is imported, it is more likely to contain MDMA. All this +suggests a possible link between recent "ecstasy" in supplies Sydney +and Dutch MDE, so it is of great interest to analyse a sample of the drug. + +Experimental: + +0.0398g of powdered "heart" tablet was suspended in 20ml H2O. The +supernatant was placed in a separating funnel with 20ml CH2Cl2, and +the residue re-extracted with ca.10ml H2O. To the combined extracts +in the funnel were added 2ml 25% NH3. After shaking, the CH2Cl2 +layer was separated, and a further three CH2Cl2 extracts of +approximately equal volume were taken. These four extracts were +combined, and evaporated under vacuum to yield 0.0121g of basic +extract as a pale yellow oil. TLC on silica using butanol/acetic acid/ +water (4:1:1) gave a single ninhydrin positive spot (violet, rf 0.55), +indicating the probable presence of only one major component. +The H1 NMR spectrum of the sample was taken, and found to +correspond identically with an authentic sample of pure MDE +having been worked up in the same manner. There was no evidence +to suggest the presence of MDMA, or other amphetamines. + +Conclusion: + +The tablets known as "hearts" and sold as "ecstasy" have been found +to contain at least 36% N-ethyl methylenedioxy amphetamine (MDE) +(calculated as the hydrochloride salt). No other active substances +were found. It is quite possible that the sample had its origin in +the Netherlands. + +___________________________________________________________________ + +Subjective differences between MDE and MDMA: + +While the effects of these two substances are sufficiently similar +to make differentiation difficult, there are some significant subjective +differences. MDE is somewhat less potent than MDMA, a typical dose +being in the range 100-160mg (as opposed to 80-140mg). At large +doses, MDE may resemble MDA (methylenedioxy amphetamine), although its +psychedelic effects are less; it is a "stoning" intoxicant, and in +particular can make walking or dancing difficult. Large doses of MDMA +can have a similar effect, although it seems that somewhat more can be +used without incurring the almost drunken intoxication. In smaller +amounts, MDE greatly resembles MDMA, although the physical and +tactile effects are generally perceived as being prevalent. +The emotional opening and empathic effects for which MDMA is +famous, although present, do not seem to be as pronounced. +As a substance of abuse at raves, MDE has the possible advantage +over MDMA that the user is less likely to embarass him/herself +in public through inappropriate empathy. On the other hand, +MDE is more likely to temporarily incapacitate the user at normal +doses. + +J + +-- + "Enjoy moderation in moderation" + +----- + +THE d88888b .a888b d8888b d8P .a888b d8888b .a888b .a8888P + d8P V8P d8P"d8P d8P V8P d8P d8P"V8P d8P V8P d8P"V8P d8P" + d88888P" d88888P d8P d8P d8P d8P 88P d8P d8P d8P 88P d8P 88P" + d8P V8b d8P d8P d8P.a8P d8P d8P.d8P d8P.a8P d8P.d8P d8P.d8P + d8P "8B, d8P d8P d8888P" d8P V888P" d888P" V888P" V888P" + + u9264582@wumpus.cc.uow.edu.au - University of Wollongong, Australia + + diff --git a/textfiles.com/drugs/mdma-lat.txt b/textfiles.com/drugs/mdma-lat.txt new file mode 100644 index 00000000..809cdd36 --- /dev/null +++ b/textfiles.com/drugs/mdma-lat.txt @@ -0,0 +1,172 @@ + LA Times 27-MAY-85 + + Psychiatrists Defend New Street Drug for Therapy + + by Miles Corwin - Times Staff Writer + +SAN FRANCISCO - Kathy Tamm was walking to her car following a meditation +class in Menlo Park when she was abducted, taken to a wooded area, tied up, +beaten, and then tortured for several hours. For six months after the +incident she underwent intensive therapy, but she showed little progress. + +She had terrible nightmares. She was terrified to leave the house. Every +unexpected noise, every shadow assaulted her senses and brought back visions +of the attack. + +Tamm, 39, a San Francisco marriage and family counselor, said she was +"suicidal, at the end of my rope." As a last resort, Tamm and her +psychiatrist decided to treat her with MDMA, and experimental drug that some +psychiatrists had found to be effective with traumatized patients. + +"I've taken it several times, and each time I felt a little less fearful," +Tamm said. "The drug helped me regain some measure of serenity and peace of +mind and enabled me to begin living a normal life again. + +"For the first time, I was able to face the experience, go back and piece +together what had happened. By facing it, instead of always burying it, I was +able to sort of slowly discharge a lot of the horror." + +Tamm's psychiatrist, Dr. Joseph Downing, and other physicians will testify at +Drug Enforcement Administration hearings in Los Angeles on June 10 and 11 in +an attempt to persuade federal authorities that MDMA has great benefits and +should be kept available for therapeutic use. The drug, which is now legal, +may soon be outlawed by the DEA. + +At the hearing, other health professionals will talk about MDMA as a popular +and dangerous new street drug. They will warn that MDMA has not been +thouroughly tested and is a source of increasing abuse and will argue that +its availability should be highly restricted. + +The hearings in Los Angeles will bring to a head the division between a small +but not vocal group of psychiatrists, therapists and professors who claim +MDMA is a useful therapeutic tool and those health professionals who see the +drug as dangerous. + +The drug, known on the street as Adam or Ecstasy, is a chemical cousin of +MDA, an illegal psychedelic drug popular in the 1960s. Users say MDMA offers +a slightly altered state of consciousness without hallucinations, heightened +sensibility without anxiety. And some psychiatrists contend that the drug is +valuable because it dissolves emotional and psychological barriers, enhances +communication, and relaxes inhibitions. + +During the last few years, MDMA has become one of the most sought-after drugs +on college campuses. The non-medical use of the drug has increased from about +10,000 doses in all of 1976 to the current 30,000 doses a month, estimated by +Ronald K. Siegel, a psychopharmacologist at the UCLA School of Medicine. + +At the Haight-Ashbury Clinic in San Francisco, several patients a month who +have taken high doses of MDMA seek treatment for symptoms similar to +"amphetamine psychosis" - paranoia, anxiety and delusions, said Darryl Inaba, +director of the clinic's drug detoxification project. + +Inaba recently received a call from a San Mateo College official who said +there was a "major outbreak" of the drug at the school and that many students +were having "panic attacks." + + Classification Protested + +The DEA has been aware of the increasing abuse, but unaware that the drug +also is being used by about 100 psychiatrists throughout the country as an +adjunct to therapy, according to Frank Sapienza, a DEA chemist. Last July the +DEA announced plans to list MDMA as a Schedule I controlled substance, the +classification for drugs with no therapeutic use and a high abuse potential, +such as LSD and heroin. + +"After the announcement," Sapienza said, "all hell broke loose." + +The DEA was deluged with letters from angry psychiatrists and therapists who +challenged the DEA's research and classification procedures. They were +outraged that the DEA plan would virtually eliminate all research and +clinical use of the drug, and they demanded a public hearing. + +A Berkeley research foundation and a group of physicians and therapists +retained a Washington law firm to challenge the proposed classification of +the drug. + +The DEA decided it was "obligated to listen to some other views," Sapienza +said. After the Los Angeles hearings, there will be others in Kansas City and +Washington, and the DEA will make a decision by 1986. + +Psychiatrists are uncomfortable discussing how they obtain MDMA. Most work +with chemists and make their own supply, and a few tell their patients to buy +it on the streets. The drug is readily available for about $30 a dose and is +now sold by many cocaine dealers in San Francisco, where the drug is more +prevalent than in the Los Angeles area, said a Haight-Ashbury Clinic +spokesman. + + Use in Treatment Defended + +The "street misuse" of the drug should not "keep it from being used +rationally in treatment," psychiatrist Downing said. Most psychiatrists who +are familiar with MDMA, Downing said, agree that some controls are needed and +suggest a classification comparable to a prescription drug like Valium. + +Dr. Philip Wolfson, a San Francisco psychiatrist who will testify in Los +Angeles, agreed that extensive testing is in order, but he believes the drug +is so useful in therapy that it should continue to be used during the years +of testing. + +"My patients didn't suddenly stand up and throw their crutches away, but I +saw some positive developments after a few sessions," he said. "Patients who +had seen only a negative, tortured world had a shift in perspective, and a +lighter, friendlier reality was momentarily available to them. For most, the +positive experience carried over after taking the drug." + +Most drugs used in psychiatry are "downers," and MDMA is unusual because it +"lightens" moods, Wolfson said. And in addition to aiding the patient, he +said, it facilitates the work of the psychiatrist. Sometimes after patients +have taken MDMA, Wolfson said, he has "accomplished the work of 20 sessions +in one afternoon." + + Defended by Monk + +Brother David Steindl-Rast, a Benedictine monk from the Immaculate Heart +Hermitage in Big Sur, tried the drug at a conference on the medical uses of +MDMA. Steindl-Rast, who was a psychologist before he entered the monastery, +said the drug facilitates the search for the "awakened attitude" all monks +seek. + +"It's like climbing all day in the fog and then suddenly, briefly seeing the +mountain peak for the first time," he said. "There are no shortcuts to the +awakened attitude, and it takes daily work and effort. But the drug gives you +a vision, a glimpse of what you are seeking." + +Siegel of UCLA, who has provided the DEA information about the street use of +MDMA, said he is skeptical when he hears of any new "wonder drug." + +"My reaction is 'Here we go again,' Siegel said. "We heard the same kinds of +things during the early days of LSD and mescaline. When PCP first came out, +it was known as the 'peace pill.' Now we know it as more of a 'war pill.' + +"in the early '70s when people were using very low doses of cocaine, a lot of +researchers had never seen a case of coke psychosis and didn't think the drug +was a health problem. Then the doses increased and so did the problems." + + Known as "Love Drug" + +Health problems associated with MDMA have been escalating as users have been +taking increasingly high doses, Siegel said. Extensive research is needed +before the drug is made available by prescription, he said, because little is +known about its long-term effects and toxicity. And, he said, MDMA has a +fairly narrow "index of safety." The dose of MDMA "that gets you high and the +dose that kills you is narrower" than many drugs, including LSD. + +MDMA (3,4-methylenedioxymethamphetamine) has a chemical composition that is +related to both amphetamine and mescaline. It is known as "the love drug" in +college campuses where it is considered to be an aphrodisiac, but users who +were interviewed said it precipitates emotional, not sexual, feelings. + +"You can't sleaze with it," said student Jeff Manning who has taken the drug +several times for "the experience." "Your true emotions come out, and +nobody's going to do something they don't want to do. It's not a scary, +trippy drug. It won't take you someplace you don't want to go." + +DEA officials should not be mislead by the "love drug" and "ecstasy" labels, +said Tamm, who used the drug several times in therapy after being assaulted. +If the drug is outlawed because of street use, she said, the harm will be +irreparable. + +"I'd hate to think that others who have gone through an experience like mine +wouldn't be able to use MDMA," she said. "I don't know what shape I'd be in +now without the drug." + \ No newline at end of file diff --git a/textfiles.com/drugs/mdma-rh.txt b/textfiles.com/drugs/mdma-rh.txt new file mode 100644 index 00000000..65ef205e --- /dev/null +++ b/textfiles.com/drugs/mdma-rh.txt @@ -0,0 +1,103 @@ + Reality Hackers/High Frontiers Issue #6, Winter 1988 + + Psychedelic Scenarios + + by Bruce Eisner and Peter Stafford + +A psychedelic soiree to benefit the Albert Hoffman Memorial Library was +recently staged at Hollywood's John Anson Ford Theater. Over two hundred +psychedelic cognoscenti, at $50 a plate, milled and mingled about on the +stage. They were later joined by an additional 1500 persons for a +presentation called "Beyond the Doors of Perception." + +Dr. Oscar Janiger, the psychiatrist noted for turning on a bevy of +celebrities and artists, compared the library to a time capsule, or fossil +record, which will contain books and memorabilia of the half century since +Hoffman made his fortuitous discovery of LSD. The library will also house a +psychedelic art gallery. Some of the art will be from artists who were turned +on by Janiger back in the late 50's and early 60's. Dr. Janiger used to give +his subjects a Hopi Kachina doll and ask each one to paint it before LSD and +again later, while on the psychedelic. + +The terrible triumvirate from Harvard, Leary, Alpert, and Metzner, came +together publicly for the first time in a quarter century. Metzner cleared up +the misconception that he, too, had been fired by Harvard. "I am happy to +point out that I wasn't fired. I didn't have a job there. I was a graduate +student. Subsequently, I changed my story because I realized it was much more +interesting if I said I was fired..." + +Richard Alpert (introduced by MC Paul Krassner as "Just Plain Ram Dass") gave +a progress report on his well-documented journey, promising another such +report ten years hence. He began by clearing up his drug-taking status. +"People have always asked me, 'Well, you have stopped using drugs, haven't +you?'" He responded, "No, I take LSD about every two years to find out what I +forgot and to have faith in who we are." He said that he would have remained +a middle-class neurotic if not for Timothy Leary and the experiences that +propelled him on his well-chronicled journey. "As long as I live, I will be +growing into what happened to me on my first psychedelic experience." + +Timothy Leary paid homage to seminal brain explorers and predicted that in +ten years, 1998 - 75% of the members of the House of Representatives and 60% +of the Supreme Court judges will have been Bob Dylan fans. He declared "The +fun has hardly begun!" + +Janiger promises the library will be open by year's end and other benefits +are in the works. If you would like to donate money, psychedelic memorabilia, +or exhibits or just want more information, write The Albert Hoffmann +Foundation, 1328 Westwood Blvd. Suite 36, Los Angeles, CA 90024. Its phone +number in L.A. is (213)470-1624 + + --- + +MDMA is in Schedule I again. The seesaw battle for MDMA's legal status may +have ended in February, with the DEA adminstrator again placing it into the +most severe category in the drug schedules. + +During the past three years, its status has resembled a ping-pong ball. Of +course, the ball always ends up back in the DEA's court and they always whack +it back into Schedule I. + +Until 1985, MDMA was as legal as table salt. After the DEA attempted to place +it in Schedule I, a group of researchers protested and hearings ensued. In +the midst of the hearings, the DEA used its new emergency powers to +temporarily ban it. Appeals courts later found this unconstitutional because, +at the time, the DEA didn't have the authority. + +At the conclusion of the hearings, the DEA's own judge recommended placing it +in the more benign Schedule III. DEa Administrator John Lawn simply ignored +the recommendation and whacked it back into Schedule I. + +The researchers - led by Lester Grinspoon, M.D. of Harvard - successfully +appealed. The First Circuit Court ruled that it should be taken off Schedule +I and reconsidered by the DEA. It did not take long for the DEA to +"reconsider" and put it back in Schedule I. At this point, those who have +opposed the scheduling are ready to give up. "When you're defanging a bear +one tooth at a time, you still got a problem," said a noted chemist and +researcher. + +Once diehard who is still hoping to get research going again is Rick Doblin +of Cambridge, Massachusetts. His organization, MAPS, has conducted animal +research to examine the charges of possible neurotoxicity lodged against +MDMA. His conclusions are contained in a report titled: "Risk Assessment: The +FDA and MDMA Research." (The report appears an an appendix to Bruce's book, +'Ecstasy: The MDMA Story' from Ronin Publishers in Berkeley, CA.) + + The non-medical use of MDMA has not stopped with its scheduling and + continues at a very significant rate in the United States while, at + the same time, MDMA has a great, but undeveloped, therapeutic + potential. If it can be demonstrated that MDMA-induced neurotoxicity + is temporary, and that there is a no-effect level around the human + dose level, the risk of using MDMA infrequently in research seems + very minimal. + + Even if neurotoxicity does occur, there are presently no behavioral + or functional effects that have been associated with it. Once careful + risk/benefit analyses can be conducted, rational decisions can be + made concerning future research. If the data comes in as preliminary + indications suggest, there can be hope that the FDA will permit + direct MDMA research in humans to begin. + +Those of you who are interested in donating time or spinal fluid to Rick's +studies can contact him at: (617)547-7271 + + \ No newline at end of file diff --git a/textfiles.com/drugs/mdma.txt b/textfiles.com/drugs/mdma.txt new file mode 100644 index 00000000..bb859e3b --- /dev/null +++ b/textfiles.com/drugs/mdma.txt @@ -0,0 +1,209 @@ + + +"Squirming in Ecstacy" + +Editor's Note: + +This article appeared in the U.C. Santa Cruz daily newspaper +earlier this year. It is not meant to be a factual report; +rather, it was intended to give the reader a little general +information about the topic. + + +One night last quarter student M was innocently doing his +homework in the Stevenson Library when he happened to look out +the window and behold a group of about 20 students innocently +squirming together in the lower Stevenson quad. Student M +innocently continued to watch this spectacle, while the squirmers +innocently continuen to squirm together for more than half an +hour. Observers and participants alike were much satisfied with +the event. + +"It was neat," said student M. + +"But it wasn't anything sexual," qualified student D, who +happened to be doing the innocent squirming. + +"They were all hugging and touching each other," recalled student +M in amazement. "It just, like, makes you really sensitive to +epidermis," explained student A, who was also taking part in the +inocent squirming. "All you want to do is touch each other's +epidermis." + +Yes, this did really happen, and these are REAL students +speaking. And no, this is not an example of what narrative +evaluatioons do to the student' intellectual capacities. What we +are talking about here is the drug MDMA (3,4, +methylenedioxymethamphetamine) - or Ecstasy, as it is more +commonly called. + +During the last year, MDMA has garnered natioonal media as the +drug that LSD should have been. Although there is as yet no +research concerning possible adverse longterm effects of MDMA, +enthusiastic users already know about the drug's immediate +effects: it induces euphoria, breaks down psychological and +social barriers, heightens physical sensatioon, increases +emotional receptivity, and generally fosters a sense of rapport +between people. Unlike psychedelics, however, MDMA is not +hallucinogenic, nor does it seem to interfere with normal +thinking and functioning. So it's reputed to offer everything +one could want from a drug, and less. And now the ultimate +touchy-feely drug has come to what is oft-touted as the nation's +last sanctuary of touchy-feeliness. + +"I'd say MDMA has become the most popular drug on campus since +the end of last year," reported student X. "Now there are at +least eight people I've heard of who are supplying MDMA on +campus." MDMA sells for about $7-15 for dose (125 milligrams) +these days and is usually in the form of a white powder taken +mxed with juice or water, though it also comes in capsule form. +MDMA is very easy to synthesize- any chemistry major could do it- +and rumor has it that some MDMA may even be manufactured in town. +Apparently the preferred mode of experiencing MDMA is with +friends, in large or small groups, and a lot of hugging and +touching goes on. + +Surprisingly perhaps, these group encounters do not devolve (or +evolve, depending on your point of view) into wild orgies. All +sources reported that MDMA did not inflame their sexual +temperaments. So much for the myth that it is an aphrodisiac. + +There seem to be two general schools of thought regarding the use +of MDMA. Recreatioonal users turn to the drug for fun- much as +you would jog, play poker, have a dinner party, or go camping in +yur RV. Personal-growth users, on the other hand, use MDMA as a +tol for personal insight. + +The recreatioonal types said mainly that MDMA is "fun," and that +iT's not as strong as MDA. They describe MDMA as being more +"cool" and mental, as compared to the hot, speedy, and +bodyrocking MDA. One student even went so far as to say that +"MDMA is a waste of time when you compare it to drugs like LSD +and MDA... It's reputatioon is overblown. I find that it doesn't +lead anyone to do things they couldn't do without the drug if +they wanted to." + +Another recreatioonal type added that "the first time you take +it, you have stars in your eyes. All you have to do is take the +dug and sit back and let the drug take you. But later, after, +after you've taken it 4 or 5 times, you have to get psyched up +for it to have any real effect." + +Personal-growth types, however, are a little more nurturant of +their practices. "I don't like those party scenes," said student +T. "There are lots of phony people around who are trying to fake +an experience because they've heard MDMA is the "Love Drug.'" She +prefers to take it only with a few close friends, to enhance +communicatioon. + +Student C thinks likewise. He first took MDMA a few weeks ago +when he was having trouble getting along with a friend. And the +cure worked: they were able to work out their differences. + +"Instead of always blocking and analyzing what someone is saying +t you," he explained, "when you're on MDMA you have a much better +communication process. You open up and understand things more +clearly. I know that sounds really hokey to someone who hasn't +done MDMA," he added, "but it's really true." + +Both recreational and personal growth types reported no real "bad +trips," though a few users reported instances in which they felt +no effect. Of the few MDMA experiences that could be ranked as +"depressing," all occured when the person taking the drug was +either alone, in bad company, or was in a bad mood to begin with. + So, as with so many other drugs, the MDMA high all depends upon +wo you take it with, and how you feel when you take it. + +Few after and side-effects were reported. One student mentioned +occasional alcohol-like hangovers, though he attributed these to +impure MDMA. Another student said he felt slightly anxious and +unsettled for about one week after the fifth time he took MDMA, +but said it could have been from something else. On the whole, +however, most users said that not only are after-effects minimal, +but in some cases the euphoria or insight of the high lingered +with them for days. + +Unfortunately, there is little scientific information available +about the effects of MDMA. Although some psychiatrists and +therapists have been giving the drug to patients to aid +doctor-patient rapport since the 1970's, little research has been +done on MDMA. Once psychiatrist who has done a few of the +published studies on the drug reported that the benefits of MDMA +include euphoria, increased energy, greater self-esteem, and less +use of alcohol and other drugs. + +However, MDMA is chemically quite similar to MDA and other +methamphetamines, which are known to damage brain cells +containing the neurotransmitters, sorotonin and dopamine. +Serotin is involved in regulating sleep, sexual behavior, mood, +aggression, and sensitivity to pain, while dopamine is involved +in initiating movement. Research shows that even a single dose +of MDA seriously debletes serotonin levels for at least two +weeks, and methamphetamines cause the degeneration of dopamine. +Wether MDMA has these same effects has not been determined. + +At any rate, when the Drug Enforcement Administration (DEA) got +wind of the fact that MDMA had hit the streets, it immediately +put a one-year moratorium on the drug. Until this coming June, +then, MDMA will be classified as a Schedule 1 illegal substance, +along with other drugs such as heroin, LSD, and MDA. These +substances are declared by the DEA to have no accepted medical +use, and a high potential for abuse. Naturally, some therapists +don't agree that MDMA has no medical use, while users among the +public don't agree that pleasure implies abuse. + +But the question of abuse really revolves around over-use. +Everyone knows that too much of anything can be harmful, and MDMA +is no exception. In the Haight-Ashbury, for instance, de-tox +clinics have reported cases of people taking 10-15 doses of MDMA +in one day. And right here in Santa Cruz one student reported +seeing friends ingest five doses in one sitting-- and with +unpleasurable results. + +UCSC Drug and Alcohol Counselor Ray Launier said he's seen three +students this year come in with complaints about MDMA +aftereffects. Consequently he has initiated a survey of student +experiences and attitudes related to MDMA. Although only Porter +ad Kresge colleges have been polled to date, Launier said that so +far, the findings reveal very few reported side-effects. Launier +cautioned that conclusions should not be drawn too swiftly. +Comparing the enamored reports of the therapeutic and insight- +bestowing qualities of MDMA to similar reports about cocaine and +LSD when those drugs first appeared, Launier said, "We've seen +this situation again and again: initially we hear nothing but +positive reports, and then later we hear about harmful +side-effects. + +----------------------------------------------------------------- + The Parking Lot BBS (415) 525-2716 +----------------------------------------------------------------- + + + + +[17]:[12:23pm] +(?=Help) Command : + ÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜÜ + Ý° The CORPORATE HQ of SHAWN-DA-LAY BOY PRODUCTIONS, inc. °Þ + Ý°  Tfile Distribution Center / MASS Megs  °Þ + Ý° 415/236/2371 RoR - Alucard 415/236/2371 °Þ + Ý° Dr. Murdock ~ Sir Death ~ Dark Nite ~ RatSnatcher ~ Pressed Rat°Þ + Ý°Shawn-Da-Lay Boy Production Inc. Rat Head Systems : 415/524/3649°Þ + Ý°°°°° The Gates of Hell are open Night and Day; °°°°°Þ + ݱ±± Ø Smooth is the Descent and Easy is the Way Ø ±±±Þ + ßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßßß + + +X-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-X + Another file downloaded from: The NIRVANAnet(tm) Seven + + & the Temple of the Screaming Electron Taipan Enigma 510/935-5845 + Burn This Flag Zardoz 408/363-9766 + realitycheck Poindexter Fortran 510/527-1662 + Lies Unlimited Mick Freen 801/278-2699 + The New Dork Sublime Biffnix 415/864-DORK + The Shrine Rif Raf 206/794-6674 + Planet Mirth Simon Jester 510/786-6560 + + "Raw Data for Raw Nerves" +X-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-X diff --git a/textfiles.com/drugs/mdma01.txt b/textfiles.com/drugs/mdma01.txt new file mode 100644 index 00000000..f12c416d --- /dev/null +++ b/textfiles.com/drugs/mdma01.txt @@ -0,0 +1,136 @@ + + + + + + + +Drug Abuse Information California Department of +and Monitoring Project Alcohol and Drug Programs + Chauncey L. Veatch III, Director + + + + + + + + + + + + + + + DRUG ABUSE SERIES + + + + + MDMA + + + + + + + + + + + + + + + + +Health and Welfare Agency State of California +Clifford L. Allenby, Secretary George Deukmejian, Governor + + +The Monograph Series which is issued by the Drug Abuse +Information and Monitoring Project is prepared for and funded by +the State of California Department of Alcohol and Drug Program +under contracts # D-0053-5 and # D-0001-7. The primary purpose +of this series is to provide information to the drug abuse +treatment community and to the general public on the epidemiology +and treatment of drug abuse. + + +The material herein does not necessarily reflect the opinions, +official policy, or position of the Department of Alcohol and +Drug Program of the State of California. The views of this study +are solely those of the authors. + + +All material in this volume except quoted passages from +copyrighted sources is in the public domain and may be used or +reproduced without permission from DAIMP or ADP or the authors. +Citation of the source is appreciated. + + + + + + + + + + + + + + + + + + MDMA + + + + + + + + + By Jerome E. Beck + + + School of Public Health + Berkeley, CA + + + Institute for Scientific Analysis + + + + + + + April 1987 + + + + + + + + + + +Edited by Elizabeth Piper Deschenes + + +X-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-X + Another file downloaded from: The NIRVANAnet(tm) Seven + + & the Temple of the Screaming Electron Taipan Enigma 510/935-5845 + Burn This Flag Zardoz 408/363-9766 + realitycheck Poindexter Fortran 510/527-1662 + Lies Unlimited Mick Freen 801/278-2699 + The New Dork Sublime Biffnix 415/864-DORK + The Shrine Rif Raf 206/794-6674 + Planet Mirth Simon Jester 510/786-6560 + + "Raw Data for Raw Nerves" +X-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-X