This is not as ambitious as the abortive FakeDBUnitTests scheme, but this one works for simple cases.
There is a new test case class UnitTestCaseUsingDatabase to inherit from. I hope it is sufficiently well documented in its PHPdocs.
* It users $CFG->unittestprefix.
* You can access that database using $this->testdb.
* That database is empty by default, you have to call create_test_table to create the ones you want, and drop_test_table to clean them up in the end. The table definitions are read from the XMLDB file.
* When you are ready to call real Moodle code that users $DB, call switch_to_test_db and then revert_to_real_db when you are done.
* If you forget to call drop_test_table or switch_to_test_db, the class will attempt to clean up after you, but will also print rude developer debug messages telling you not to be stupid.
* There is also a load_test_data method for populating a table from an array.
The is an example of its use in lib/simpletest/testunittestusingdb.php.