diff --git a/src/wp-admin/css/list-tables.css b/src/wp-admin/css/list-tables.css
index 2cb19dcd6c..3b9bb0e945 100644
--- a/src/wp-admin/css/list-tables.css
+++ b/src/wp-admin/css/list-tables.css
@@ -797,7 +797,7 @@ p.pagenav {
 }
 
 .row-actions {
-	color: #dcdcde;
+	color: #a7aaad;
 	font-size: 13px;
 	padding: 2px 0 0;
 	position: relative;
diff --git a/src/wp-admin/includes/class-wp-plugin-install-list-table.php b/src/wp-admin/includes/class-wp-plugin-install-list-table.php
index 9c5f382e9d..59bce7b8d1 100644
--- a/src/wp-admin/includes/class-wp-plugin-install-list-table.php
+++ b/src/wp-admin/includes/class-wp-plugin-install-list-table.php
@@ -586,31 +586,38 @@ class WP_Plugin_Install_List_Table extends WP_List_Table {
 								_x( 'Active', 'plugin' )
 							);
 						} elseif ( current_user_can( 'activate_plugin', $status['file'] ) ) {
-							$button_text = __( 'Activate' );
-							/* translators: %s: Plugin name. */
-							$button_label = _x( 'Activate %s', 'plugin' );
-							$activate_url = add_query_arg(
-								array(
-									'_wpnonce' => wp_create_nonce( 'activate-plugin_' . $status['file'] ),
-									'action'   => 'activate',
-									'plugin'   => $status['file'],
-								),
-								network_admin_url( 'plugins.php' )
-							);
-
-							if ( is_network_admin() ) {
-								$button_text = __( 'Network Activate' );
+							if ( $compatible_php && $compatible_wp ) {
+								$button_text = __( 'Activate' );
 								/* translators: %s: Plugin name. */
-								$button_label = _x( 'Network Activate %s', 'plugin' );
-								$activate_url = add_query_arg( array( 'networkwide' => 1 ), $activate_url );
-							}
+								$button_label = _x( 'Activate %s', 'plugin' );
+								$activate_url = add_query_arg(
+									array(
+										'_wpnonce' => wp_create_nonce( 'activate-plugin_' . $status['file'] ),
+										'action'   => 'activate',
+										'plugin'   => $status['file'],
+									),
+									network_admin_url( 'plugins.php' )
+								);
 
-							$action_links[] = sprintf(
-								'<a href="%1$s" class="button activate-now" aria-label="%2$s">%3$s</a>',
-								esc_url( $activate_url ),
-								esc_attr( sprintf( $button_label, $plugin['name'] ) ),
-								$button_text
-							);
+								if ( is_network_admin() ) {
+									$button_text = __( 'Network Activate' );
+									/* translators: %s: Plugin name. */
+									$button_label = _x( 'Network Activate %s', 'plugin' );
+									$activate_url = add_query_arg( array( 'networkwide' => 1 ), $activate_url );
+								}
+
+								$action_links[] = sprintf(
+									'<a href="%1$s" class="button activate-now" aria-label="%2$s">%3$s</a>',
+									esc_url( $activate_url ),
+									esc_attr( sprintf( $button_label, $plugin['name'] ) ),
+									$button_text
+								);
+							} else {
+								$action_links[] = sprintf(
+									'<button type="button" class="button button-disabled" disabled="disabled">%s</button>',
+									_x( 'Cannot Activate', 'plugin' )
+								);
+							}
 						} else {
 							$action_links[] = sprintf(
 								'<button type="button" class="button button-disabled" disabled="disabled">%s</button>',
diff --git a/src/wp-admin/includes/class-wp-plugins-list-table.php b/src/wp-admin/includes/class-wp-plugins-list-table.php
index 9b74ca3c38..a5831dad17 100644
--- a/src/wp-admin/includes/class-wp-plugins-list-table.php
+++ b/src/wp-admin/includes/class-wp-plugins-list-table.php
@@ -739,6 +739,12 @@ class WP_Plugins_List_Table extends WP_List_Table {
 		$restrict_network_active = false;
 		$restrict_network_only   = false;
 
+		$requires_php = isset( $plugin_data['RequiresPHP'] ) ? $plugin_data['RequiresPHP'] : null;
+		$requires_wp  = isset( $plugin_data['RequiresWP'] ) ? $plugin_data['RequiresWP'] : null;
+
+		$compatible_php = is_php_version_compatible( $requires_php );
+		$compatible_wp  = is_wp_version_compatible( $requires_wp );
+
 		if ( 'mustuse' === $context ) {
 			$is_active = true;
 		} elseif ( 'dropins' === $context ) {
@@ -792,14 +798,21 @@ class WP_Plugins_List_Table extends WP_List_Table {
 					}
 				} else {
 					if ( current_user_can( 'manage_network_plugins' ) ) {
-						$actions['activate'] = sprintf(
-							'<a href="%s" id="activate-%s" class="edit" aria-label="%s">%s</a>',
-							wp_nonce_url( 'plugins.php?action=activate&amp;plugin=' . urlencode( $plugin_file ) . '&amp;plugin_status=' . $context . '&amp;paged=' . $page . '&amp;s=' . $s, 'activate-plugin_' . $plugin_file ),
-							esc_attr( $plugin_id_attr ),
-							/* translators: %s: Plugin name. */
-							esc_attr( sprintf( _x( 'Network Activate %s', 'plugin' ), $plugin_data['Name'] ) ),
-							__( 'Network Activate' )
-						);
+						if ( $compatible_php && $compatible_wp ) {
+							$actions['activate'] = sprintf(
+								'<a href="%s" id="activate-%s" class="edit" aria-label="%s">%s</a>',
+								wp_nonce_url( 'plugins.php?action=activate&amp;plugin=' . urlencode( $plugin_file ) . '&amp;plugin_status=' . $context . '&amp;paged=' . $page . '&amp;s=' . $s, 'activate-plugin_' . $plugin_file ),
+								esc_attr( $plugin_id_attr ),
+								/* translators: %s: Plugin name. */
+								esc_attr( sprintf( _x( 'Network Activate %s', 'plugin' ), $plugin_data['Name'] ) ),
+								__( 'Network Activate' )
+							);
+						} else {
+							$actions['activate'] = sprintf(
+								'<span>%s</span>',
+								_x( 'Cannot Activate', 'plugin' )
+							);
+						}
 					}
 
 					if ( current_user_can( 'delete_plugins' ) && ! is_plugin_active( $plugin_file ) ) {
@@ -846,14 +859,21 @@ class WP_Plugins_List_Table extends WP_List_Table {
 					}
 				} else {
 					if ( current_user_can( 'activate_plugin', $plugin_file ) ) {
-						$actions['activate'] = sprintf(
-							'<a href="%s" id="activate-%s" class="edit" aria-label="%s">%s</a>',
-							wp_nonce_url( 'plugins.php?action=activate&amp;plugin=' . urlencode( $plugin_file ) . '&amp;plugin_status=' . $context . '&amp;paged=' . $page . '&amp;s=' . $s, 'activate-plugin_' . $plugin_file ),
-							esc_attr( $plugin_id_attr ),
-							/* translators: %s: Plugin name. */
-							esc_attr( sprintf( _x( 'Activate %s', 'plugin' ), $plugin_data['Name'] ) ),
-							__( 'Activate' )
-						);
+						if ( $compatible_php && $compatible_wp ) {
+							$actions['activate'] = sprintf(
+								'<a href="%s" id="activate-%s" class="edit" aria-label="%s">%s</a>',
+								wp_nonce_url( 'plugins.php?action=activate&amp;plugin=' . urlencode( $plugin_file ) . '&amp;plugin_status=' . $context . '&amp;paged=' . $page . '&amp;s=' . $s, 'activate-plugin_' . $plugin_file ),
+								esc_attr( $plugin_id_attr ),
+								/* translators: %s: Plugin name. */
+								esc_attr( sprintf( _x( 'Activate %s', 'plugin' ), $plugin_data['Name'] ) ),
+								__( 'Activate' )
+							);
+						} else {
+							$actions['activate'] = sprintf(
+								'<span>%s</span>',
+								_x( 'Cannot Activate', 'plugin' )
+							);
+						}
 					}
 
 					if ( ! is_multisite() && current_user_can( 'delete_plugins' ) ) {
@@ -945,10 +965,8 @@ class WP_Plugins_List_Table extends WP_List_Table {
 
 		}
 
-		$requires_php   = isset( $plugin_data['requires_php'] ) ? $plugin_data['requires_php'] : null;
-		$compatible_php = is_php_version_compatible( $requires_php );
-		$class          = $is_active ? 'active' : 'inactive';
-		$checkbox_id    = 'checkbox_' . md5( $plugin_file );
+		$class       = $is_active ? 'active' : 'inactive';
+		$checkbox_id = 'checkbox_' . md5( $plugin_file );
 
 		if ( $restrict_network_active || $restrict_network_only || in_array( $status, array( 'mustuse', 'dropins' ), true ) || ! $compatible_php ) {
 			$checkbox = '';
@@ -968,7 +986,9 @@ class WP_Plugins_List_Table extends WP_List_Table {
 			$plugin_name = $plugin_data['Name'];
 		}
 
-		if ( ! empty( $totals['upgrade'] ) && ! empty( $plugin_data['update'] ) ) {
+		if ( ! empty( $totals['upgrade'] ) && ! empty( $plugin_data['update'] )
+			|| ! $compatible_php || ! $compatible_wp
+		) {
 			$class .= ' update';
 		}
 
@@ -1190,6 +1210,62 @@ class WP_Plugins_List_Table extends WP_List_Table {
 
 		echo '</tr>';
 
+		if ( ! $compatible_php || ! $compatible_wp ) {
+			printf(
+				'<tr class="plugin-update-tr">' .
+				'<td colspan="%s" class="plugin-update colspanchange">' .
+				'<div class="update-message notice inline notice-error notice-alt"><p>',
+				esc_attr( $this->get_column_count() )
+			);
+
+			if ( ! $compatible_php && ! $compatible_wp ) {
+				_e( 'This plugin doesn&#8217;t work with your versions of WordPress and PHP.' );
+				if ( current_user_can( 'update_core' ) && current_user_can( 'update_php' ) ) {
+					printf(
+						/* translators: 1: URL to WordPress Updates screen, 2: URL to Update PHP page. */
+						' ' . __( '<a href="%1$s">Please update WordPress</a>, and then <a href="%2$s">learn more about updating PHP</a>.' ),
+						self_admin_url( 'update-core.php' ),
+						esc_url( wp_get_update_php_url() )
+					);
+					wp_update_php_annotation( '</p><p><em>', '</em>' );
+				} elseif ( current_user_can( 'update_core' ) ) {
+					printf(
+						/* translators: %s: URL to WordPress Updates screen. */
+						' ' . __( '<a href="%s">Please update WordPress</a>.' ),
+						self_admin_url( 'update-core.php' )
+					);
+				} elseif ( current_user_can( 'update_php' ) ) {
+					printf(
+						/* translators: %s: URL to Update PHP page. */
+						' ' . __( '<a href="%s">Learn more about updating PHP</a>.' ),
+						esc_url( wp_get_update_php_url() )
+					);
+					wp_update_php_annotation( '</p><p><em>', '</em>' );
+				}
+			} elseif ( ! $compatible_wp ) {
+				_e( 'This plugin doesn&#8217;t work with your version of WordPress.' );
+				if ( current_user_can( 'update_core' ) ) {
+					printf(
+						/* translators: %s: URL to WordPress Updates screen. */
+						' ' . __( '<a href="%s">Please update WordPress</a>.' ),
+						self_admin_url( 'update-core.php' )
+					);
+				}
+			} elseif ( ! $compatible_php ) {
+				_e( 'This plugin doesn&#8217;t work with your version of PHP.' );
+				if ( current_user_can( 'update_php' ) ) {
+					printf(
+						/* translators: %s: URL to Update PHP page. */
+						' ' . __( '<a href="%s">Learn more about updating PHP</a>.' ),
+						esc_url( wp_get_update_php_url() )
+					);
+					wp_update_php_annotation( '</p><p><em>', '</em>' );
+				}
+			}
+
+			echo '</p></div></td></tr>';
+		}
+
 		/**
 		 * Fires after each row in the Plugins list table.
 		 *